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1
A biochemical study into the selective recruitment of Rubisco activase into the pyrenoid
Published 2024“…Here, we characterized the recruitment of C. reinhardtii Rca (CrRca) into the C. reinhardtii pyrenoid by utilizing our in vitro reconstitution consisting of EPYC1 and CrRubisco. …”
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Thesis-Doctor of Philosophy -
2
A pragmatic approach to mobile attention bias modification in a clinical setting
Published 2023“…These were planned for in order to mitigate against the risk of recruitment and attrition, and they helped to revise the methods for the definitive trial. …”
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Thesis-Doctor of Philosophy -
3
Structural studies of human telomerase complexes by cryo-electron microscopy
Published 2020“…Although many studies were carried out to study human telomerase, the molecular mechanisms behind telomerase biogenesis, recruitment and elongation process are still not fully understood. …”
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Thesis-Doctor of Philosophy -
4
Structural investigation of macromolecular assembly by adaptive and innate immune regulators using cryo-EM
Published 2022“…The cryo-EM reconstructed 3D model of NLRP6 reveals how it undergoes conformational changes to facilitate inflammasome recruitment and propagation, suggesting its molecular basis in the protection of the gut. …”
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Thesis-Doctor of Philosophy -
5
Understanding the motivations to become a public humanities or social studies secondary school teacher in Singapore: a mixed methods based study
Published 2022“…Also, broadly, the survey and interview findings largely align with previous findings on material drivers (e.g. job salary) and non-material drivers (e.g. service to society) of PSM. Furthermore, a recruitment framework designed specifically for humanities and social studies secondary school teacher recruiters to better hire such teachers who can inculcate critical thinking and soft skills in their students for the knowledge-based economy, is proposed. …”
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Thesis-Doctor of Philosophy -
6
Automated socio-cognitive assessment of patients with schizophrenia and depression
Published 2022“…The first study was conducted from 2014 to 2016, which included the recruitment of the cohort. The study was conducted with 58 patients with schizophrenia and 29 healthy controls over three sessions: at week 0, week 2, and week 12. …”
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Thesis-Doctor of Philosophy -
7
Chaperone-assisted multiphase condensation of RNA-binding-deficient TDP-43
Published 2024“…Moreover, there was sequential recruitment of chaperones to the TDP-43 condensates, suggesting that the Hsp40 plays a pivotal role in the initial condensation process. …”
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Thesis-Doctor of Philosophy -
8
MYC overexpression in cancer increases chromatin interactions at superenhancers and c-Myc binding sites
Published 2022“…At the same time, the recruitment of c-Myc and other transcription factors may stabilize chromatin interactions to increase chromatin contact frequency. …”
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Thesis-Doctor of Philosophy -
9
Characterization of a rubisco condensate derived from the red type pyrenoid of Phaeodactylum tricornutum
Published 2023“…Phatr3_J47612 and its fragments partition into PYCO1 condensates and antagonize the recruitment of PtRubisco. The likely next steps in this project would be directed towards a systematic study of the interplay of several pyrenoidal proteins to develop our understanding of the diatom CCM.…”
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Thesis-Doctor of Philosophy -
10
Mechanoregulation of angiopoietin-like 4 in epithelial-mesenchymal transition and cancer metastasis
Published 2024“…Here, we revealed the PIP2-regulated recruitment of DAP12 homodimer to lipid raft boundary of NK cells. …”
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Thesis-Doctor of Philosophy -
11
The role of Agrin in tumor angiogenesis
Published 2020“…Though several proteoglycans have been implicated in cancer and angiogenesis, their roles in endothelial cell (EC) recruitment and vascularization during tumorigenesis remain poorly understood. …”
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Thesis-Doctor of Philosophy -
12
Electron microscopy and biochemical analysis of native telomeric chromatin
Published 2019“…Telomeric DNA acts as a platform for the recruitment of a six protein-complex called shelterin. …”
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Thesis-Doctor of Philosophy -
13
A study of lipid-mediated clustering of oncogenic Ras proteins on cell membrane using nanotopography engineering
Published 2022“…Recently, membrane curvature has been identified to be a key membrane property to regulate Ras recruitment and nanoclustering by coordinating with lipids and Ras binding partners. …”
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Thesis-Doctor of Philosophy -
14
Biotemplate approach for synthesizing nanomaterials for energy storage applications
Published 2020“…In particular, the moss plant provides a suitable surface chemistry that can be used to recruit metallic precursors. Utilizing this capability of the moss plant, successful functional nanomaterials were synthesized with complex compositions (LVP and LNMO). …”
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Thesis-Doctor of Philosophy -
15
Nongenetic engineering of subcellular targeted therapeutic agents to facilitate precise cell activity manipulation
Published 2022“…The localization of such agents within the complex three-dimensional cellular structure has substantial implications in the precise activation of signal transduction and recruitment of functional components to regulate cell events and stress responses. …”
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Thesis-Doctor of Philosophy -
16
Recognition of nucleosomes by protein factors that regulate chromatin structure and dynamics
Published 2020“…This automodification and PAR attachment to other nuclear factors evokes a cascade cellular response that leads to recruitment of additional DNA repair factors and chromatin remodeling machinery to the site of DNA damage. …”
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Thesis-Doctor of Philosophy -
17
Collaborative model of care between orthopaedics and allied healthcare professional trial (CONNACT)
Published 2024“…Progression criteria for the primary aim to be fulfilled were developed prior to patient recruitment. 20 patients were recruited (10 intervention, 10 control) with the intervention arm reporting better improvements at 12-weeks compared to the control arm. …”
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Thesis-Doctor of Philosophy -
18
Fear-based health messages for Malay diabetes patients in Singapore
Published 2021“…In Phase II, 100 patients were recruited and asked to rank the stimuli according to three emotion metrics: valence, arousal and dominance. …”
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Thesis-Doctor of Philosophy -
19
Interventions to promote diversity in the workplace
Published 2023“…Chapter 3 examined whether the default effect can nudge recruiters to select more diverse candidates when hiring.…”
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Thesis-Doctor of Philosophy -
20
Design and evaluation of a video retrieval environment for exploratory searches in a learning context
Published 2020“…Study 1 explored the video seeking behavior of these adolescents and identify the video seeking process. 14 post-secondary students were recruited to perform two exploratory video search tasks while applying the think-aloud technique. …”
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Thesis-Doctor of Philosophy