J. Zijlmans, Hond en baas. Een geschiedenis van haat en liefde by H.C. Vrielink

Get full text

J. Zijlmans, Hond en baas. Een geschiedenis van haat en liefde by H.C. Vrielink

Get full text

Ph.H. Breuker, A. Janse, Negen eeuwen Friesland-Holland. Geschiedenis van een haat-liefdeverhouding by W. Pelt

Get full text

Ph.H. Breuker, A. Janse, Negen eeuwen Friesland-Holland. Geschiedenis van een haat-liefdeverhouding by W. Pelt

Get full text

Human Alpha 1 Antitrypsin Suppresses NF-κB Activity and Extends Lifespan in Adult <i>Drosophila</i> by Ye Yuan, Max Van Belkum, Alana O’Brien, Alain Garcia, Karla Troncoso, Ahmed S. Elshikha, Lei Zhou, Sihong Song

Subjects: “…human alpha-1 antitrypsin (hAAT)…”
Get full text

The moderating effect of the interaction between joint audit and accounting conservatism on the association between corporate governance and corporate performance by Ahmed Elmashtawy, Mohd Hassan Che Haat, Shahnaz Ismail, Faozi A. Almaqtari

Get full text

Accelerated Wound Border Closure Using a Microemulsion Containing Non-Inhibitory Recombinant α1-Antitrypsin by Alon Gimmon, Lior Sherker, Lena Kojukarov, Melodie Zaknoun, Yotam Lior, Tova Fadel, Ronen Schuster, Eli C. Lewis, Eldad Silberstein

“…Here, wound healing was examined in the presence of recombinant hAAT (hAAT^WT) and protease-inhibition-lacking hAAT (hAAT^CP). …”
Get full text

A Novel Cellular Therapy to Treat Pancreatic Pain in Experimental Chronic Pancreatitis Using Human Alpha-1 Antitrypsin Overexpressing Mesenchymal Stromal Cells by Rebecca P. Chow, Kevin Nguyen, Wenyu Gou, Erica Green, Katherine Morgan, William Lancaster, Kristi Helke, Charlie Strange, Hongjun Wang

“…MSC or hAAT-MSC infusion reduced abdominal pain sensitivities. hAAT-MSC therapy also suppressed TRPV1 expression in DRG and reduced pancreatic mast cell density induced by TNBS. …”
Get full text

Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model by Atkinson Mark A, Satoh Minoru, Wasserfall Clive H, Choi Young-Kook, Grimstein Christian, Brantly Mark L, Campbell-Thompson Martha, Song Sihong

“…These mice were pretreated either with hAAT protein or with recombinant adeno-associated virus vector expressing hAAT (rAAV-hAAT). …”
Get full text

Proteomic Analysis of Exosomes Secreted from Human Alpha-1 Antitrypsin Overexpressing Mesenchymal Stromal Cells by Hua Wei, Erica Green, Lauren Ball, Hongkuan Fan, Jennifer Lee, Charlie Strange, Hongjun Wang

“…Nanoparticle tracking analysis (NTA) showed that the particle size of the EVs from control MSCs or hAAT-MSCs ranged from 30 to 200 nm. Both MSCs and hAAT-MSCs expressed exosome-associated proteins, including CD63, CD81, and CD9. hAAT-MSCs also expressed high levels of hAAT. …”
Get full text

Alpha-1 Antitrypsin Reduces Disease Progression in a Mouse Model of Charcot-Marie-Tooth Type 1A: A Role for Decreased Inflammation and ADAM-17 Inhibition by Nikolay Zhukovsky, Marianna Silvano, Thierry Filloux, Sergio Gonzalez, Karl-Heinz Krause

“…Here, we tested whether treatment with human AAT (hAAT) would have a therapeutic effect on CMT1A in a <i>PMP22</i> transgenic mouse model. …”
Get full text

The Result of Vitamin C Treatment of Patients with Cancer: Conditions Influencing the Effectiveness by János Hunyady

“…We believe that the clinical use of HAAT in cancer treatment should be reassessed. The accumulation of more study results on HAAT is desperately needed.…”
Get full text

Human Alpha-1 Antitrypsin Attenuates ENaC and MARCKS and Lowers Blood Pressure in Hypertensive Diabetic db/db Mice by Carlos I. Lugo, Lauren P. Liu, Niharika Bala, Angelica G. Morales, Mohammed F. Gholam, Julia C. Abchee, Nasseem Elmoujahid, Ahmed Samir Elshikha, Rigena Avdiaj, Louis A. Searcy, Nancy D. Denslow, Sihong Song, Abdel A. Alli

“…First, we show hAAT administration results in reduced blood pressure in diabetic db/db mice compared to vehicle treatment in both the inactive and active cycles. …”
Get full text

The unfolded protein response to PI*Z alpha‐1 antitrypsin in human hepatocellular and murine models by Yuanqing Lu, Liqun R. Wang, Jungnam Lee, Naweed S. Mohammad, Alek M. Aranyos, Calvin Gould, Nazli Khodayari, Regina A. Oshins, Craig G. Moneypenny, Mark L. Brantly

“…Additionally, novel full‐length genomic DNA PI*Z hAAT and PI*M hAAT transgenic mouse models were established. …”
Get full text

Mouse characteristics that affect establishing xenografts from hepatocellular carcinoma patient biopsies in the United States by Chenhui Zou, Imane El Dika, Koen O. A. Vercauteren, Marinela Capanu, Joanne Chou, Jinru Shia, Jill Pilet, Corrine Quirk, Gadi Lalazar, Linda Andrus, Mohammad Kabbani, Amin Yaqubie, Danny Khalil, Taha Mergoub, Luis Chiriboga, Charles M. Rice, Ghassan K. Abou‐Alfa, Ype P. de Jong

“…Mice with macroscopically detectable PDX showed rising human alpha1‐antitrypsin (hAAT) serum levels, and conversely, no PDX was observed in mice with undetectable hAAT. …”
Get full text

An Inclusive Workplace Approach to Disability through Assistive Technologies: A Systematic Review and Thematic Analysis of the Literature by Tiziana Marinaci, Claudio Russo, Giulia Savarese, Giovanna Stornaiuolo, Filomena Faiella, Luna Carpinelli, Marco Navarra, Giuseppina Marsico, Monica Mollo

“…Overall, the use of the HAAT model highlighted a lack of studies on the affective and socio-cultural dimensions that characterize the use of AT in the workplace. …”
Get full text

Correction of F8 intron 1 inversion in hemophilia A patient-specific iPSCs by CRISPR/Cas9 mediated gene editing by Zhiqing Hu, Yong Wu, Rou Xiao, Junya Zhao, Yan Chen, Lingqian Wu, Miaojin Zhou, Desheng Liang

“…The iPSCs were differentiated into hepatocyte-like cells (HPLCs).Results: The hAAT promoter and exon one were targeted addition in HA-iPSCs with a high efficiency of 10.19% via HMEJ. …”
Get full text

Household consumption expenditure behaviour towards outside ready-made food: Evidence from Bangladesh by Md. Rashid Ahmed

“…People generally eat snacks and sample ready-made foods from local shops and the Haat/Bazar (market). Empirical evidence based on Cragg's double-hurdle model assesses that secondary or higher school education, family size, and annual food expenditure are important determinants of the likelihood of household participation in consumption and spending on eating out in the past week. …”
Get full text

Monitoring of Wheat Crop Growth at Farm Level Using Time Series Multispectral Satellite Imagery by Baljit Singh, Bhavya Chauhan, Sandeep Kumar Kaushik, Varun Narayan Mishra

Get full text

Antiviral therapy effectively improves liver hemodynamics as evidenced by serum biomarker and contrast-enhanced ultrasound examinations in patients with hepatitis B cirrhosis by Xiaoyong Xu, Chaoxue Zhang, Chen Shi, Naizhong Hu, Bin Sun, Derun Kong, Jianming Xu

“…Peripheral blood vWF and sCD163, as well as liver ultrasound Doppler parameters including portal vein diameter (PVD), portal vein velocity (PVV), portal vein congestion index (PV-CI), hepatic vein damping index (HV-DI), hepatic arterial arrival time (HAAT), hepatic vein arrival time (HVAT) and intrahepatic cycle time (HV-HA), were measured at the baseline and the follow-up periods. …”
Get full text