Virgin olive oil phenolics extract inhibit invasion of HT115 human colon cancer cells in vitro and in vivo by Hashim, Yumi Zuhanis Has-Yun, Worthington, Jenny, Allsopp, Philip, Ternan, Nigel G., Brown, Emma M., McCann, Mark J., Rowland, Ian R., Esposto, Sonia, Servili, Maurizio, Gill, Chris I. R.

“…Collectively, the data suggest that – possibly through modulation of integrin expression – OVP decreases invasion in vitro and also inhibits metastasis in vivo.…”
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A central bioactive region of LTBP-2 stimulates the expression of TGF-β1 in fibroblasts via akt and p38 signalling pathways by Sideek, Mohamed Arshad, Smith, Joshua J., Menz, Clementine, Adams, Julian R. J., Cowin, Allison J., Gibson, Mark A.

“…However, TGF-β1 upregulation was partially inhibited by anti-αVβ3 integrin antibodies, suggestive of a direct or indirect role for this integrin. …”
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