Nicotinamide Nucleotide Transhydrogenase as a novel treatment target in adrenocortical carcinoma by Chortis, Vasileios, Taylor, Angela E., Doig, Craig L., Walsh, Mark D., Meimaridou, Eirini, Jenkinson, Carl, Rodriguez-Blanco, Giovanny, Ronchi, Cristina L., Jafri, Alisha, Metherell, Louise A., Hebenstreit, Daniel, Dunn, Warwick B., Arlt, Wiebke, Foster, Paul A.

“…To explore this, we transiently knocked down NNT in NCI-H295R ACC cells. As predicted, this manipulation increased intracellular levels of oxidative stress; this resulted in a pronounced suppression of cell proliferation and higher apoptotic rates, as well as sensitization of cells to chemically induced oxidative stress. …”
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Islington disability and long-term health conditions employment project: final report by Lewis, Jane, Fernando, Sandra, Nyby, Josefine, Yu, Qicheng, Gay, Dionne, Flynn, Jimmy

“…And then I went on to further education and I felt I was just completely knocked.’ (Deaf focus group participant) • Literacy – levels of literacy, especially literacy in the use of English amongst deaf participants whose first language is British Sign Language (BSL), was raised as a barrier to accessing employment and recruitment processes…”
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