A perspective on nanomedicine: focus on cardiovascular medicine by Shrestha, Sony C., White, Kenneth, Minelli, Caterina, Tewfik, Ihab, Thapa, Panna, Tewfik, Sundus

“…Approach: Despite the widespread prevalence of cardiovascular diseases (CVDs), limitations remain in their clinical management regardless of the major technological advancement in diagnostic and therapeutic modalities available. …”
Get full text

Animal models used in the research of nanoparticles for cardiovascular diseases by Shang, Lijun, Dong, Caijuan, Ma, Aiqun

“…Cardiovascular disease (CVD) is the leading cause of mortality and morbidity worldwide. …”
Get full text

Roles and mechanisms of renalase in cardiovascular disease: a promising therapeutic target by Li, Yue, Wu, Weidong, Liu, Weihong, Zhou, Mingxue

“…Cardiovascular disease (CVD) is prevalent worldwide and remains a leading cause of death. …”
Get full text

Effects of blueberry consumption on cardiovascular health in healthy adults: a cross-over randomised controlled trial by Wang, Yueyue, Gallegos, Jose Lara, Haskell-Ramsay, Crystal, Lodge, John K.

“…Blueberries are rich in polyphenols, and their effect on cardiovascular health, including risk factors for endothelial dysfunction and hypertension, has been investigated in interventional studies. …”
Get full text

Meal replacement by formula diet reduces weight more than a lifestyle intervention alone in patients with overweight or obesity and accompanied cardiovascular risk factors—the ACOORH trial by Halle, Martin, Röhling, Martin, Banzer, Winfried, Braumann, Klaus-Michael, Kempf, Kerstin, McCarthy, H. David, Schaller, Nina, Predel, Hans-Georg, Scholze, Jürgen, Führer-Sakel, Dagmar, Toplak, Hermann, Berg, Aloys

“…Background: As formula diets have demonstrated to be effective in reducing weight, we hypothesised that in patients with overweight or obesity and accompanied cardiovascular risk factors, combining a liquid formula diet with a lifestyle intervention is superior in reducing weight and improving cardiovascular risk factors than lifestyle intervention alone. …”
Get full text

Nutriepigenetics and cardiovacular disease by Kalea, Anastasia Z., Drosatos, Konstantinos, Buxton, Jessica L.

“…Purpose of review: We present a current perspective of epigenetic alterations that can lead to cardiovascular disease (CVD) and the potential of dietary factors to counteract their actions. …”
Get full text

Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not by Williams, Jack L., Paudyal, Anju, Awad, Sherine, Nicholson, James, Grzesik, Dominika, Botta, Joaquin, Meimaridou, Eirini, Maharaj, Avinaash, Stewart, Michelle, Tinker, Andrew, Cox, Roger D., Metherell, Louise A.

“…The C57BL/6J and C57BL/6N mice have well-documented phenotypic and genotypic differences, including the infamous nicotinamide nucleotide transhydrogenase (Nnt) null mutation in the C57BL/6J substrain, which has been linked to cardiovascular traits in mice and cardiomyopathy in humans. …”
Get full text

Cardiopulmonary outcomes in people with impaired lung function: the role of metabolic syndrome by Sadeghimakki, Roham, Tahrani, Abd A.

“…Impaired lung function, either with airflow limitation or with preserved ratio impaired spirometry (PRISm), is common globally and associated with increased cardiorespiratory morbidity, cause-specific mortality and overall mortality.1,2 In this context, understanding the impact of metabolic syndrome on cardiopulmonary outcomes is clinically important, given the growing global prevalence of metabolic syndrome, driven in part by the increasing obesity rates, and its associations with major adverse cardiovascular events and all-cause mortality.…”
Get full text

Biological factors linking ApoE ε4 variant and severe COVID-19 - letter to the Editor by Inal, Jameel

“…The recent review by Moriarty et al. [1] provided a very pertinent analysis of the increased risks from thromboses and other cardiovascular complications of patients with elevated levels of lipoprotein(a) (Lp(a)) following coronavirus disease 2019 (COVID-19). …”
Get full text

COVID‐19 comorbidities, associated procoagulant extracellular vesicles and venous thromboembolisms: a possible link with ethnicity? by Inal, Jameel

“…In a meta-analysis of seven studies (1,576 infected patients) the co-morbidities included hypertension (21.1%), diabetes (9.7%), cardiovascular disease (CVD), (8.4%) and respiratory system disease (1.5%). …”
Get full text

Determinants of exercise intention and behaviour in individuals diagnosed with schizophrenia using a revised version of the Theory of Planned Behaviour by Twyford, Jessica Louise

“…Objective: The physical inactivity of people with schizophrenia, presents a risk for cardiovascular disease and other physical and mental health problems. …”
Get full text

Formulation and characterization of phytostanol ester solid lipid nanoparticles for the management of hypercholesterolemia: an ex vivo study by Shrestha, Sony C., Ghebremeskel, Kebreab, White, Kenneth, Minelli, Caterina, Tewfik, Ihab, Thapa, Panna, Tewfik, Sundus

“…This can contribute to better management of one of the main risk factors of cardiovascular diseases.…”
Get full text

Effects of acute and chronic exercise on immunological parameters in the elderly aged: can physical activity counteract the effects of aging? by Sellami, Maha, Gasmi, Maha, Denham, Joshua, Hayes, Lawrence D., Stratton, Dan, Padulo, Johnny, Bragazzi, Nicola

“…Moreover, these alterations decrease the response to pathogens, which leads to several age-related diseases including cardiovascular disease, Alzheimer's disease, and diabetes in older individuals. …”
Get full text

Development of muscle mass and body fat reference curves for white male UK firefighters by Lessons, Greg Richard, Bhakta, Dee, McCarthy, H. David

“…These references offer a novel improvement upon the limitations of BMI and BF% for the benefit of an occupational group at elevated risk of cardiovascular disease.…”
Get full text

Cold indoor temperatures and their association with health and well-being: a systematic literature review by Janssen, H., Ford, K., Gascoyne, Ben, Hill, R., Roberts, M., Bellis, M. A., Azam, S.

“…Study outcomes included cardiovascular (blood pressure, electrocardiogram abnormalities, blood platelet count), respiratory (chronic obstructive pulmonary disease symptoms, respiratory viral infection), sleep, physical performance and general health. …”
Get full text

Age-related electrocardiographic characteristics of male junior soccer athletes by Cavarretta, Elena, Sciarra, Luigi, Biondi-Zoccai, Giuseppe, Maffessanti, Francesco, Nigro, Antonia, Sperandii, Fabio, Guerra, Emanuele, Quaranta, Federico, Fossati, Chiara, Peruzzi, Mariangela, Pingitore, Annachiara, Stasinopoulos, Dimitrios, Rigby, Robert A., Adorisio, Rachele, Saglietto, Andrea, Calò, Leonardo, Frati, Giacomo, Pigozzi, Fabio

Get full text

Lipids and fatty acid composition of early and term healthy placenta with a specific focus on foetal growth development by Bitsanis, Demetrios

“…The experimental data strongly support the hypotheSiS that disturbance in utero environment through inadequate maternal essential fatty acid lipid nutrition impaired tissue synthesis DHA and/or AA in the offspring and. hence. may set the offspring at high risk for the development of cardiovascular disorders later in life.…”
Get full text

The health needs of the Greek Cypriot people living in two London boroughs by Papadopoulos, Irena

“…The health and lifestyle survey provides statistical information which has not been available thus far, and whilst some of the findings should be viewed with caution, some are statistically significant and generalisable. Cardiovascular disease is the number one cause of morbidity; over 40% of the sample population were overweight whilst 60% of the sample population led sedentary lives; the incidence of smoking is higher than in the rest of the population; stress levels are also very high. …”
Get full text

Development, validation and implementation of a novel dietary salt monitor in type 2 diabetes in UK by Babber, Ranjana

“…The risk of cardiovascular morbidity and mortality increases manyfold in Type 2 diabetes, owing to the higher prevalence rates of hypertension. …”
Get full text

Improved characterisation of measures of fatness and metabolic risks in older adolescents and young adults in the South Asian population in the UK by Moqueem, Erum

“…The higher percentage of body fat (BF%) in SA children tends to track into adult life and consequently increases the risk of type 2 diabetes and cardiovascular disease. Across infancy, childhood, adolescence and even young adulthood, overweight and obesity are defined using statistically derived cut-off values, typically using centile charts based upon age and gender specific reference data. …”
Get full text