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Phenotypic Evolution of Therapeutic Salmonella enterica Serovar Typhimurium after Invasion of TRAMP Mouse Prostate Tumor
Published 2014“…Thus, we have made an initial examination of selected phenotypes in a therapeutic Salmonella enterica serovar Typhimurium population developed from an archival wild-type LT2 strain and intraperitoneally injected into a 6-month-old TRAMP (transgenic adenocarcinoma of mouse prostate) mouse. …”
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Activation of tolerogenic dendritic cells in the tumor draining lymph CD8+ T cells engineered to express CD40 ligand
Published 2012“…The antitumor CD8[supersript +] T cell response was further enhanced if TRAMP mice were also immunized with a tumor-specific Ag. …”
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Creating a New Malaria Vaccine Design that uses a Blood Stage P. falciparum Chassis for Non-Blood Stage Antigen Presentation
Published 2024“…Plasmids using the conditional translation repressor system TetR-DOZI were created, and transgenic parasites that express the scaffold protein eTRAMP4 fused to either CSP or P25 were generated. …”
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Persistence of tumor-infiltrating CD8 T cells is tumor-dependent but antigen-independent
Published 2012“…We have previously developed a modified TRansgenic Adenocarcinoma of the Mouse Prostate (TRAMP) model where prostate cancer cells express the T-cell epitope SIYRYYGL (SIY) recognized by CD8 T cells expressing the 2C T-cell receptor (TCR) (referred to as TRP-SIY mice). …”
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Carbon in Solution and the Charpy Impact Performance of Medium Mn Steels
Published 2023“…Interface segregation, e.g., of tramp elements, was investigated as a potential cause and none was found. …”
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Prescriptive analytics in operations problems : a tree ensemble approach
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Thesis