Towards the use of localised delivery strategies to counteract cancer therapy–induced cardiotoxicities by Monahan, David S., Almas, Talal, Wyile, Robert, Cheema, Faisal H., Duffy, Garry P., Hameed, Aamir

“…There is an urgent need to mitigate cardiac disease that occurs as a result of cancer therapy. …”
Get full text

Towards the use of localised delivery strategies to counteract cancer therapy–induced cardiotoxicities by Monahan, David S., Almas, Talal, Wyile, Robert, Cheema, Faisal H., Duffy, Garry P., Hameed, Aamir

“…There is an urgent need to mitigate cardiac disease that occurs as a result of cancer therapy. …”
Get full text

Meta-Analysis of Cardiac Mortality in Three Cohorts of Carbon Black Production Workers by Morfeld, Peter, Mundt, Kenneth, Dell, Linda, Sorahan, Tom, McCunney, Robert J

“…Our results do not demonstrate that airborne CB exposure increases all-cause or cardiac disease mortality.…”
Get full text

Getting to the heart of the matter: long non-coding RNAs in cardiac development and disease by Scheuermann, Johanna C., Boyer, Laurie Ann

“…Similarly, many adult cardiac diseases involve transcriptional changes and sometimes have a developmental basis. …”
Get full text
Get full text

Integrated Analysis of Contractile Kinetics, Force Generation, and Electrical Activity in Single Human Stem Cell-Derived Cardiomyocytes by Kijlstra, Jan David, Hu, Dongjian, Mittal, Nikhil, van der Meer, Peter, Garakani, Arman, Domian, Ibrahim J., Kausel, Eduardo A.

“…Accordingly, our approach has the potential for broad application in the study of cardiac disease, drug discovery, and cardiotoxicity screening.…”
Get full text

A novel totivirus and piscine reovirus (PRV) in Atlantic salmon (Salmo salar) with cardiomyopathy syndrome (CMS) by Lovoll, Marie, Wiik-Nielsen, Jannicke, Grove, Soren, Wiik-Nielsen, Christer R., Kristoffersen, Anja B., Faller, Randi, Poppe, Trygve, Jung, Joonil, Pedamallu, Chandra S., Nederbragt, Alexander J., Meyerson, Matthew L., Rimstad, Espen, Tengs, Torstein

“…We recently reported the finding and the complete genomic sequence of a novel piscine reovirus (PRV), which is associated with another cardiac disease in Atlantic salmon; heart and skeletal muscle inflammation (HSMI). …”
Get full text

SCIP: software for efficient clinical interpretation of copy number variants detected by whole-genome sequencing by Ding, Qiliang, Somerville, Cherith, Manshaei, Roozbeh, Trost, Brett, Reuter, Miriam S., Kalbfleisch, Kelsey, Stanley, Kaitlin, Okello, John B. A., Hosseini, S. M., Liston, Eriskay, Curtis, Meredith, Zarrei, Mehdi, Higginbotham, Edward J., Chan, Ada J. S., Engchuan, Worrawat, Thiruvahindrapuram, Bhooma, Scherer, Stephen W., Kim, Raymond H., Jobling, Rebekah K.

“…SCIP was comprehensively evaluated using WGS data from 1027 families with congenital cardiac disease and/or autism spectrum disorder, containing 187 pathogenic or likely pathogenic (P/LP) CNVs identified in previous curations. …”
Get full text

DeepStrain Evidence of Asymptomatic Left Ventricular Diastolic and Systolic Dysfunction in Young Adults With Cardiac Risk Factors by Morales, Manuel A., Snel, Gert J. H., van den Boomen, Maaike, Borra, Ronald J. H., van Deursen, Vincent M., Slart, Riemer H. J. A., Izquierdo-Garcia, David, Prakken, Niek H. J., Catana, Ciprian

“…DeepStrain was trained and tested using short-axis cine-MRI images from healthy subjects and patients with cardiac disease. Subsequently, subjects aged 18–45 years were prospectively recruited and classified among age- and gender-matched groups: risk factor group (RFG) 1 including overweight without hypertension or type 2 diabetes; RFG2 including hypertension without type 2 diabetes, regardless of overweight; RFG3 including type 2 diabetes, regardless of overweight or hypertension. …”
Get full text