Showing 1 - 20 results of 74 for search '"germ cell"', query time: 0.08s Refine Results
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    Genetics of germ cell development by Lesch, Bluma J., Page, David C

    Published 2014
    “…The germ line represents a continuous cellular link between generations and between species, but the germ cells themselves develop in a specialized, organism-specific context. …”
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    Retinoic Acid and Germ Cell Development in the Ovary and Testis by Endo, Tsutomu, Mikedis, Maria M., Nicholls, Peter K., Page, David C, de Rooij, Dirk G.

    Published 2020
    “…These gametes derive from primordial germ cells, which colonize the nascent gonad, and later undertake sexual differentiation to produce oocytes or sperm. …”
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    Mammalian germ cells are determined after PGC colonization of the nascent gonad by Nicholls, Peter K., Schorle, Hubert, Naqvi, Sahin, Hu, Yueh-Chiang, Fan, Yuting, Carmell, Michelle A., Page, David C.

    Published 2020
    “…Mammalian primordial germ cells (PGCs) are induced in the embryonic epiblast, before migrating to the nascent gonads. …”
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    Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors by Chen, Di, Sun, Na, Hou, Lei, Kim, Rachel, Faith, Jared, Aslanyan, Marianna, Tao, Yu, Zheng, Yi, Fu, Jianping, Liu, Wanlu, Kellis, Manolis, Clark, Amander

    Published 2021
    “…The foundation of this model is the quality of the first progenitors called primordial germ cells (PGCs), which in vivo are specified during the peri-implantation window of human development. …”
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    Licensing of Primordial Germ Cells for Gametogenesis Depends on Genital Ridge Signaling by Hu, Yueh-Chiang, Nicholls, Peter K., Soh, Ying Qi Shirleen, Daniele, Joseph R., Junker, Jan Philipp, van Oudenaarden, Alexander, Page, David C

    Published 2015
    “…In mouse embryos at mid-gestation, primordial germ cells (PGCs) undergo licensing to become gametogenesis-competent cells (GCCs), gaining the capacity for meiotic initiation and sexual differentiation. …”
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    A transitory signaling center controls timing of primordial germ cell differentiation by Banisch, Torsten U, Slaidina, Maija, Gupta, Selena, Ho, Megan, Gilboa, Lilach, Lehmann, Ruth

    Published 2022
    “…During Drosophila ovary morphogenesis, primordial germ cells (PGCs) either are sequestered in stem cell niches and are maintained in an undifferentiated germline stem cell state or transition directly toward differentiation. …”
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    Dynamic and regulated TAF gene expression during mouse embryonic germ cell development by Gura, Megan A., Mikedis, Maria M., Seymour, Kimberly A., de Rooij, Dirk G., Page, David C, Freiman, Richard N.

    Published 2020
    “…The expression of several of these germ cell-enriched TFIID genes is dependent upon Dazl and/or Stra8, known regulators of germ cell development and meiosis. …”
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    Isolating mitotic and meiotic germ cells from male mice by developmental synchronization, staging, and sorting by Romer, Katherine A., de Rooij, Dirk G., Page, David C.

    Published 2020
    “…Isolating discrete populations of germ cells from the mouse testis is challenging, because the adult testis contains germ cells at every step of spermatogenesis, in addition to somatic cells. …”
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