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The stomach in health and disease
Published 2017“…The stomach is traditionally regarded as a hollow muscular sac that initiates the second phase of digestion. …”
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Ingestible, Controllable, and Degradable Origami Robot for Patching Stomach Wounds
Published 2016“…In his paper, we present origami-based robots that can be ingested into the stomach, locomote to a desired location, patch a wound, remove a foreign body, deliver drugs, and biodegrade. …”
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Stomach tissue classification using autofluorescence spectroscopy and machine learning
Published 2023“…Abstract Background and objectives Determination of stomach tumor location and invasion depth requires delineation of gastric histological structure, which has hitherto been widely accomplished by histochemical staining. …”
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Programmable Medicine: Autonomous, Ingestible, Deployable Hydrogel Patch and Plug for Stomach Ulcer Therapy
Published 2021“…Gastric ulcer is a chronic and complex (and often complete) erosion of the stomach wall that happens as a complication of a previous chronic, inflammatory process. …”
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Loss of Tight Junction Protein Claudin 18 Promotes Progressive Neoplasia Development in Mouse Stomach
Published 2020“…CLDN18 regulates cell lineage differentiation and cellular signaling in mouse stomach; CLDN18-knockout mice develop intraepithelial neoplasia and then large and focally dysplastic polypoid tumors in the absence of H pylori infection.…”
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Helminth co-infection in Helicobacter pylori infected INS-GAS mice attenuates gastric premalignant lesions of epithelial dysplasia and glandular atrophy and preserves colonization resistance of the stomach to lower bowel microbiota
Published 2015“…Identifying how helminths reduce gastric premalignant lesions and impact bacterial colonization of the H. pylori infected stomach could lead to new treatment strategies to inhibit progression from chronic gastritis to cancer in humans.…”
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Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial Cells
Published 2021“…The aim here was to investigate paracellular permeability defects in stomach mucosa from claudin-18 knockout (Cldn18-KO) mice. …”
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Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric Epithelial Cells
Published 2022“…The aim here was to investigate paracellular permeability defects in stomach mucosa from claudin-18 knockout (Cldn18-KO) mice. …”
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IL-11 is a parietal cell cytokine that induces atrophic gastritis
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Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier
Published 2018“…Mechanisms that regulate tight junction function and structure in the normal stomach, or dysfunction in the infected stomach, however, are largely unknown. …”
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Development of an Ingestible Fluid Wicking Gastric Electrical Stimulation Platform for Hormone Modulation
Published 2023“…Thus far, these methods have utilized invasive implant procedures in order to stimulate the outer muscle layers of the stomach. The development of non-invasive stimulation approaches requires that these systems be in an ingestible form factor that instead stimulate the inner mucosal layer of the stomach. …”
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Design of a large-dose minimally invasive drug delivery device for Tuberculosis
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Design of Motor Controller for Intragastric Applications
Published 2022“…This thesis showcases the design and possible utility of an intragastric motor controller which has the capability to remain within the stomach for long periods of time performing simple tasks or acting as a long term stomach health monitor. …”
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Gut-associated microbial symbionts of the marsh fiddler crab, Uca pugnax
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Ingestible transiently anchoring electronics for microstimulation and conductive signaling
Published 2021“…To demonstrate interaction with stomach muscle tissue, we used the electrical stimulation to induce acute muscular contractions. …”
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Oral Biologic Delivery: Advances Toward Oral Subunit, DNA, and mRNA Vaccines and the Potential for Mass Vaccination During Pandemics
Published 2022“…The gastrointestinal (GI) tract presents a number of prospective mucosal inductive sites for vaccine targeting, including the oral cavity, stomach, and small intestine. However, currently available oral vaccines are effectively limited to live-attenuated and inactivated vaccines against enteric diseases. …”
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Oral Biologic Delivery: Advances Toward Oral Subunit, DNA, and mRNA Vaccines and the Potential for Mass Vaccination During Pandemics
Published 2022“…The gastrointestinal (GI) tract presents a number of prospective mucosal inductive sites for vaccine targeting, including the oral cavity, stomach, and small intestine. However, currently available oral vaccines are effectively limited to live-attenuated and inactivated vaccines against enteric diseases. …”
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