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    Novel phytochemical antibiotic conjugates as multitarget inhibitors of pseudomononas aeruginosa GyrB/ParE and DHFR by Jayaraman, Premkumar, Lim, ChuSing, Siddiqi, Mohammad Imran, Sakharkar, Kishore R., Dhillon, Sarinder K., Sakharkar, Meena K.

    Published 2014
    “…Furthermore, docking and dynamics simulations revealed that the designed compounds have favorable binding affinity and stability in both the ATP-binding sites of GyrB/ParE and the folate-binding site of DHFR, by forming strong hydrogen bonds and hydrophobic interactions with key active site residues. …”
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    Journal Article
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