Employment of micropatterned hydrogels to regulate the redox status of mesenchymal stem cells by Lee, Melissa Kao Hui

“…It was observed that isolating cell spreading and substrate stiffness ultimately leads to the same effect of reduced Ras homolog gene family, member A (RhoA) activation which subsequently allows for elevated Ras-related C3 botulinum toxin substrate 1 (Rac1) activity, which is a major binding partner in NOX generation of ROS. …”
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