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Imaging method by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) for tissue or tumor: a mini review
Published 2023“…Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is an ad-vanced technique that uses minimum fragmented ions from complex molecules for mass spectrome-try (MS) analysis (tissue profiling by mass spectrometry). …”
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Journal Article -
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Conjugation of polyethylene glycol to ferritin nanocage
Published 2015“…Two conditions were tested to optimize the conjugation reaction and the modified protein cage was characterized by dynamic light scattering (DLS), matrix assisted laser desorption/ionization time-of-flight (MALDI TOF) mass spectrometry and transmission electron microscopy (TEM). …”
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Thesis -
4
Nanoparticle behaviours in different biological media
Published 2016“…The presence of corona was identified using Fourier Transform Infrared Spectroscopy (FTIR) and Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF). …”
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Final Year Project (FYP) -
5
Reduced graphene oxide films used as matrix of MALDI-TOF-MS for detection of octachlorodibenzo-p-dioxin
Published 2012“…A reduced graphene oxide (rGO) film was used as the matrix in the matrix-assisted laser desorption/ionization time-of-flight mass spectroscopy (MALDI-TOF-MS) for the detection of octachlorodibenzo-p-dioxin (OCDD) with a detection weight as low as 500 pg.…”
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Journal Article -
6
Accurate detection of SNPs using base-specific cleavage and mass spectrometry
Published 2013“…Among many others, one valuable approach for SNP detection is based on the base-specific cleavage of single-stranded nucleic acids followed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis. …”
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Conference Paper -
7
New molecules for solar cells
Published 2011“…Characterization of these derivatives was done by Matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry, Thermal gravimetric analysis (TGA), Differential scanning calorimetry (DSC), Nuclear magnetic resonance (NMR) spectroscopy (1H, 13C), Ultraviolet-visible (UV-Vis) spectroscopy, Cyclic voltammetry (CV) and Polarised optical microscopy (POM). …”
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Final Year Project (FYP) -
8
Differentiation of achyranthes bidentata and cyathula officinalis using peptidomic fingerprinting with multivariate analyses
Published 2018“…This study aimed to characterize cysteine-rich peptides from these two species, and construct a rapid and accurate classification model to differentiate them using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) coupling with multivariate analyses. …”
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Final Year Project (FYP) -
9
Extraction and characterization of titanium dioxide nanoparticles from commercially available sunscreens
Published 2021“…After the extraction, scanning electron microscopy (SEM) with energy dispersive x-ray (EDX) and x-ray powder diffraction (XRD) characterisation techniques confirmed the presence of TiO2 nanoparticles in the samples. Matrix-assisted laser desorption/ionization with time of flight (MALDI-TOF) suggested the extracted TiO2 nanoparticles were coated. …”
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Final Year Project (FYP) -
10
A novel approach to study polymorphism of microsatellite loci in humans
Published 2013“…Thus, in the present study, we aimed to analyze Y-specific poly(CA/GT)n designated YCAI, YCAII, and YCAIII (early reported regions) and a new CA repeat region YCAIV selected by NCBI Y-chromosome database analysis by “etandem” software using a novel approach of PCR-matrix assisted laser desorption/ionization- time-of-flight mass spectrometry (MALDI-TOF MS). [1st Award]…”
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Student Research Poster -
11
Comprehensive Study on Chain-End Transformation of Polymer–Iodides with Amines for Synthesizing Various Chain-End Functionalized Polymers
Published 2017“…This reaction was comprehensively studied for three different polymers, i.e., poly(butyl acrylate), polystyrene, and poly(methyl methacrylate), and six different functional amines with phenyl, alkyl, triethoxysilyl, SH, OH, and NH2 functionalities, and the detailed reaction mechanisms were probed by using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI–TOF–MS). …”
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Journal Article -
12
Cysteine-rich peptide fingerprinting as a general method for herbal analysis to differentiate Radix Astragali and Radix Hedysarum
Published 2020“…Herein, we describe a rapid and general method using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), coupled with multivariate analyses to differentiate herbal medicines. …”
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Journal Article -
13
Understanding the protein corona on engineered nanoparticles used in food products
Published 2017“…Analytical tools which include Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-ToF MS), micro Bicinchoninic Acid (BCA) Protein Assay Kit, Thermal Gravimetric Analysis (TGA) and Fourier Transform Infrared (FTIR) spectroscopy were used to evaluate the amount and identity of the protein corona. …”
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Final Year Project (FYP) -
14
Comparative differences in the behavior of TiO2 and SiO2 food additives in food ingredient solutions
Published 2019“…Corona adsorption studies were carried out using multiple complementary methods including Fourier transform infrared (FTIR) spectroscopy, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF-MS), transmission electron microscopy (TEM), micro bicinchoninic acid (BCA) protein assay, and thermogravimetric analysis (TGA). …”
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Journal Article -
15
Efficient analysis of small molecules via laser desorption/Ionization time-of-flight mass spectrometry (LDI-TOF MS) using gold nanoshells with nanogaps
Published 2024“…Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a commonly used technique for analyzing large biomolecules. …”
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Journal Article -
16
Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
Published 2017“…PNAs are purified by reverse-phase HPLC, followed by molecular weight characterization by matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF). …”
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Journal Article -
17
Extraction of cage-like sporopollenin exine capsules from dandelion pollen grains
Published 2018“…Preservation of SEC morphology and successful removal of proteinaceous materials was evaluated using scanning electron microscopy (SEM), matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry, elemental CHN analysis, dynamic image particle analysis (DIPA) and confocal laser scanning microscopy (CLSM). …”
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Journal Article -
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Chain-end modification of polymer-iodide synthesized via organocatalyzed living radical polymerization and its application in functional materials
Published 2020“…Two representative polymers, i.e., poly(butyl acrylate) and polystyrene, were comprehensively studied and the reaction mechanism was also probed through matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) analysis. …”
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Thesis-Doctor of Philosophy -
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Functional block copolymers, heterogeneous catalysts and chain-end functionalized polymers in organocatalyzed living radical polymerization
Published 2020“…The chain-end transformations were comprehensively studied via matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). …”
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Thesis-Doctor of Philosophy -
20
Novel assays for detection and characterization of soluble proteases
Published 2021“…Better peptides were subsequently identified by screening random peptide libraries using a high-throughput technique named Self-Assembled Monolayer for Matrix-Assisted Laser-Desorption–Ionization Mass Spectrometry (SAMDI-MS). …”
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Thesis-Doctor of Philosophy