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Leaf morphogenesis: the multifaceted roles of mechanics
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Journal Article -
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Problem-solving environments for biological morphogenesis
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Journal Article -
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Morphogenesis of the branching reef coral Madracis mirabilis
Published 2013“…Simulation experiments and isotope analyses of M. mirabilis skeletons indicate that external gradients of dissolved inorganic carbon (DIC) determine the morphogenesis of branching, phototrophic corals. In the simulations we use a first principle model of accretive growth based on local interactions between the polyps. …”
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Conference Paper -
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Src-mediated phosphorylation of βpix-b regulates dendritic spine morphogenesis
Published 2019“…PAK-interacting guanine nucleotide exchange factor (βPix; also known as Arhgef7) has been implicated in many actin-based cellular processes, including spine morphogenesis in neurons. However, the molecular mechanisms by which βPix controls spine morphology remain elusive. …”
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Imaging analysis of human metapneumovirus-infected cells provides evidence for the involvement of F-actin and the raft-lipid microdomains in virus morphogenesis
Published 2015“…The similarity between HMPV morphogenesis and the closely related human respiratory syncytial virus suggests that involvement of F-actin and lipid-raft microdomains in virus morphogenesis may be a common feature of the Pneumovirinae.…”
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Journal Article -
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An in silico, in vitro and in vivo study of the structural and functional features of SARS small protein E and its contribution to viral morphogenesis and apoptosis.
Published 2010“…All coronaviruses encode a small hydrophobic envelope (E) protein, which mediates viral assembly and morphogenesis by an unknown mechanism. When E proteins are synthesized alone, they reconfigure intracellular membranous organelles or induce secretion of exosomal vesicles when overexpressed. …”
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Research Report -
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Investigating the role of heartless/FGF signalling pathway in the proximal satellite glia and L5 neurons of the drosophila optic lobe
Published 2023“…Additionally, we also found that the migration of psgs into the lamina, and the morphogenesis of psgs to wrap around the L5 neurons did not appear to be determined by Htl/FGF signalling pathway. …”
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Final Year Project (FYP) -
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Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly
Published 2017“…Respiratory syncytial virus (RSV) is an enveloped virus that assembles into filamentous virus particles on the surface of infected cells. Morphogenesis of RSV is dependent upon cholesterol-rich (lipid raft) membrane microdomains, but the specific role of individual raft molecules in RSV assembly is not well defined. …”
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Journal Article -
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Spatiotemporal oscillation in confined epithelial motion upon fluid-to-solid transition
Published 2022“…Our findings may shed light on the geometrical and nanomechanical control of tissue morphogenesis and growth.…”
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Physical forces guide curvature sensing and cell migration mode bifurcating
Published 2024“…The molecular flows and curved front morphogenesis are sustained by coordinated cellular tension generation and transmission. …”
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The role of CRTC genes in the development of the zebrafish embryo
Published 2012“…Biological functions of CRTC1 have been associated with cancer metastasis, neuronal morphogenesis in mouse and longevity in C.elegans. However, the role of CRTC1 in zebrafish embryonic development has not been characterized yet. …”
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Final Year Project (FYP) -
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Novel transcriptional regulators of neuroblast self-renewal in Drosophila larval brains
Published 2018“…These results provide a starting point in studying neuroblast morphogenesis, allowing us to further construct the complexed network controlling stem cell self-renewal. …”
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Final Year Project (FYP) -
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Functional morphometric analysis in cellular behaviors : shape and size matter
Published 2014“…Cellular morphogenesis in response to biophysical and topographical cues provides insights into cytoskeletal status, biointerface communications, and phenotypic adaptations in an incessant signaling feedback that governs cellular fate. …”
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Journal Article -
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Understanding the formation of the wavy edges in plants leaves
Published 2020“…Leaf patterns are formed when plants undergo morphogenesis, where differential growth occur at the cellular level. …”
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Final Year Project (FYP) -
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Role of cysteines in infectious bronchitis virus envelope protein oligomerization.
Published 2010“…Coronavirus envelope E protein plays an important role in the virus assembly and morphogenesis. Despite of little sequence homology among the coronavirus E protein family, two or three cysteines located near the C-terminal side of the transmembrane domain are conserved in all E proteins. …”
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Final Year Project (FYP) -
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Programming Cell Death in the 1960s: Developmental Biology beyond Dichotomy
Published 2018“…Its broad importance in many biological and pathological phenomena, including morphogenesis, autoimmune disease, and cancer, demonstrates that its origin deserves a historical examination. …”
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Nanomechanical force mapping of restricted cell-to-cell collisions oscillating between contraction and relaxation
Published 2020“…Contact-mediated cell migration strongly determines the invasiveness of the corresponding cells, collective migration, and morphogenesis. The quantitative study of cellular response upon contact relies on cell-to-cell collision, which rarely occurs in conventional cell culture. …”
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Journal Article