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Virtual screening, molecular docking, molecular dynamics, and MM-GBSA approaches identify prospective fructose-1,6-bisphosphatase inhibitors from pineapple for diabetes management
Published 2023“…Glu20, Ala24, Thr27, Gly28, Glu29, Leu30, Val160, Met177, Asp178, and Cys179 were identified as key amino acids that stabilized the human liver FBPase-butane-2,3-diyl diacetate complex, while Tyr215 and Asp218 played a crucial role in the human liver FBPase-Metformin complex. …”
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Hepatitis C virus (HCV) diagnosis via microfluidics
Published 2021“…One such severe issue that could cause significant damage to the human liver is the hepatitis C virus (HCV). Several techniques are available to detect HCV under various categories, such as detection through antibodies, antigens, and RNA. …”
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Formulation, characterization and biological activity screening of sodium alginate-gum arabic nanoparticles loaded with curcumin
Published 2020“…Cytotoxicity was performed using MTT assay to measure their potential in inhibiting the cell growth and the result demonstrated a significant anticancer activity of Cur/ALG-GANPs against human liver cancer cells (HepG2) than in colon cancer (HT29), lung cancer (A549) and breast cancer (MCF7) cells. …”
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Immobilization of Hepatitis B Antibody Onto the Reduced Graphene Oxide
Published 2015“…Hepatitis B (Hep B) is a viral infection caused by hepatitis B virus (HBV) that infects the human liver. HBV is bloodborne and transfusion-transmitted human pathogen that has a large impact on blood safety and public health worldwide. …”
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