β-mangostin suppresses LA-7 cells proliferation in vitro and in vivo: involvement of antioxidant enzyme modulation; suppression of matrix metalloproteinase and α6β4 integrin signalling pathways by Mohan, Suvitha Syam, Abdul, Ahmad Bustamam, Mohd Hashim, Najihah, Ghaderian, Mostafa, Hobani, Yahya Hasan, Makeen, Anwar, Abdelwahab, Siddig Ibrahim, Mohan, Syam

“…Moreover, the reduction of both 14-3-3β and ITGB4 genes indicated the involvement of α6β4 integrin signalling pathway. These findings showed that β-mangostin is a promising compound candidate as an anti-tumour agent against breast cancer.…”
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Isolation, purification and cryopreservation of spermatogonial stem cells from testis of azoospermia patients by Mirzapour, Tooba

“…Isolated SSCs were positive for spermatogonial cell markers such as Oct4, Dazl, Stra8, Piwil2, Vasa and α6-Integrin, but negative about Nanog and β1-Integrin Genes. …”
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Protective effects of Phyllanthus amarus against lipopolysaccharide-induced neuroinflammation and cognitive impairment in rats by Alagan, Akilandeshwari, Jantan, Ibrahim, Kumolosasi, Endang, Ogawa, Satoshi, Abdullah, Maizaton Atmadini, Azmi, Norazrina

“…At the end of the behavioral tests, the levels of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, nitric oxide (NO), inducible nitric oxide synthase (iNOS), CD11b/c integrin expression, and synaptophysin immunoreactivity were determined in the brain tissues. …”
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Xeno-free culture of human pluripotent stem cells on oligopeptide-grafted hydrogels with various molecular designs by Chen, Yen-Ming, Chen, Li-Hua, Li, Meng-Pei, Li, Hsing-Fen, Higuchi, Akon, Kumar, S. Suresh, Ling, Qing-Dong, Alarfaj, Abdullah A., Munusamy, Murugan A., Chang, Yung, Benelli, Giovanni, Murugan, Kadarkarai, Umezawa, Akihiro

“…Oligopeptide sequences were selected from integrin- and glycosaminoglycan-binding domains of the extracellular matrix. …”
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TGF-β-induced fibrosis: a review on the underlying mechanism and potential therapeutic strategies by Ong, Chun Hao, Tham, Chau Ling, Harith, Hanis Hazeera, Firdaus, Nazmi, Israf, Daud Ahmad

“…There are also neutralizing monoclonal antibodies that can target the TGF-β ligands or αvβ6 integrin to prevent binding to receptor or activation of latent TGF-β respectively. …”

Quantitative proteomics analysis revealed compromised chicken dendritic cells function at early stage of very virulent infectious Bursal disease virus infection by Abdul Raham, Nor Yasmin, Omar, Abdul Rahman, Mohd Isa, Noor Farhanah, Hiscox, Julian, Yeap, Swee Keong

“…At the later stage of infection, vvIBDV induced expression of several proteins, namely CD200 receptor 1-A, integrin alpha-5, HSP-90, cathepsin, lysosomal-associated membrane protein, and Ras-related proteins, which play crucial roles in signaling, apoptosis, stress response, and antigen processing as well as in secretion of danger-associated proteins. …”
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Characterization of candidate proteins involved in calreticulin-dependent invasion using breast cancer tissue biopsies by Noudehi, Zahra Yekta Moghaddam

“…CRT is a high-capacity calcium-binding protein found in the endoplasmic reticulum (ER) lumen and has been implicated in a variety of functions outside of the ER, including cell adhesion and integrin-dependent calcium signaling. CRT has been found to be over-expressed in cancers including breast cancer. …”
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In vitro and in vivo anti-lung cancer properties of leaf ethanolic extract of morinda citrifolia l. by Lim, Swee Ling

“…The MLE suppressed lung and liver cancer invasive migration or metastasis via down-regulating angiogenesis biochemical pathways (EGFR, MMP9 and integrin). The 300 mg/kg body-weight MLE significantly (and dose-dependently) suppressed lung tumour growth, more effectively than the 50 mg/kg body-weight Erlotinib treatment for most of the parameters measured. …”
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Association of gene polymorphisms and XPD expression on risk of nasopharyngeal carcinoma and survival among Malaysians by Ban, Eng Zhuan

“…ITGA2 is the alpha subunit of the transmembrane receptor integrin and is mainly responsible for cell-cell and cellextracellular matrix interaction. …”
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Isolation, characterization and quantitative proteomics analysis of chicken dendritic cells following infection with infectious bursal disease virus by Abd Rahaman, Nor Yasmin

“…Most of the protein functions that were impaired at 3 hpi were related to signaling, stress response and immune response, for instance integrin α and β, heat shock proteins (HSPs) especially HSP90α and HSP60. …”
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Role of RhoGDIα on migration and invasion of estrogen receptor positive MCF7 and estrogen receptor negative MDA-MB-231 breast cancer cells by Hooshmand, Somayeh

“…However, not much is known on the function of adenine phosphoribosyl transferase, dCTP pyrophosphatase 1, fumaryl acetoacetate hydrolase domain-containing protein 1, Proteasome subunit beta type-4, GTP-binding protein SAR1a, Protein Hikeshi, Integrin alpha-M, GrpE protein homolog 1 mitochondrial in breast cancer. …”
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