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JNK signaling pathways is required for mitochondrial dysfunction-induced iinsulin resistance in WRL-68 human liver cell
Published 2015“…Therefore, the aim of this study was to investigate the therapeutic roles of JNK signaling pathways inhibition upon mitochondrial dysfunction-induced insulin resistance in WRL-68 human liver cells. We found that JNK inhibitor (SP600125) exhibits ameliorative properties in cells treated with rotenone, mitochondrial complex I inhibitor via enhancement of insulin stimulated-glucose uptake activity. …”
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The cytotoxicity effect of Nephelium lappaceum leaves extract on human cancer cells
Published 2016“…In order to test its anticancer activity, human liver (HepG2) and lung (A549) cancer cell lines were cultured and tested with different concentrations of the crude extract. …”
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Effects of zingiber officinale on superoxide dismutase, glutathione peroxidase, catalase, glutathione and malondialdehyde content in HepG2 cell line
Published 2005“…The objective of this study is to measure activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), glutathione (GSH) and malondialdehyde (MDA) content in human liver cancer cell line (HepG2) and normal liver cell line (WRL-68) treated with Zingiber officinale extract. …”
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Cellular functional roles of celastrol on mitochondrial dysfunction-induced insulin resistance
Published 2015“…The optimum doses of celastrol in improving insulin-stimulated glucose uptake of mitochondrial inhibitors-treated 3T3-L1 adipocytes, human skeletal muscle and C3A human liver cells were 5, 15 and 30 nM, respectively. …”
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5
Phytochemical, in vitro and in silico analyses of hexanic alpinia galanga extract in cancer chemo-prevention study on breast cancer cells
Published 2020“…Cytotoxicity of crude extracts were screened by using MTT assay against normal human liver (WRL-68), and MCF-7, MDA-MB-231 and MDA-MB-468 breast cancer cell lines. …”
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Thesis