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Pathological features and neuroinflammatory mechanisms of SARS-CoV-2 in the brain and potential therapeutic approaches
Published 2022“…Neurological manifestations and serious neurodegeneration occur through the binding of spike proteins to ACE2 receptor. …”
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Carbon nanotubes and graphene as emerging candidates in neuroregeneration and neurodrug delivery
Published 2015“…Neuroregeneration is the regrowth or repair of nervous tissues, cells, or cell products involved in neurodegeneration and inflammatory diseases of the nervous system like Alzheimer’s disease and Parkinson’s disease. …”
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3
Molecular docking and acetylcholinesterase inhibitory activity of psoralen derivatives
Published 2020“…However, due to the complex nature of AD, standard drugs with AChE inhibitors such as galanthamine, donepezil, rivastigmine and tacrine can only alleviate the symptoms but cannot cure neurodegeneration. Thus, it is significant to develop multifunctional drugs which are Multi-Target Directed Ligands (MTDLs) as the best approach for the treatment of AD. …”
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Multi-method analysis of medical records and MRI images for early diagnosis of dementia and alzheimer’s disease based on deep learning and hybrid methods
Published 2021“…Dementia and Alzheimer’s disease are caused by neurodegeneration and poor commu-nication between neurons in the brain. …”
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