(AT)n is an interspersed repeat in the Xenopus genome. by Greaves, D, Patient, R

“…We have observed (AT)34 and (AT)23 tracts close to the coding sequences of the Xenopus laevis tadpole alpha T1 and adult beta 1 globin genes, respectively. …”

A simplified method of generating transgenic Xenopus by Sparrow, D, Latinkic, B, Mohun, T

Distinct origins of adult and embryonic blood in Xenopus. by Ciau-Uitz, A, Walmsley, M, Patient, R

“…Whether embryonic and adult blood derive from a single (yolk sac) or dual (yolk sac plus intraembryonic) origin is controversial. Here, we show, in Xenopus, that the yolk sac (VBI) and intraembryonic (DLP) blood compartments derive from distinct blastomeres in the 32-cell embryo. …”

Genetic control of hematopoietic development in Xenopus and zebrafish. by Ciau-Uitz, A, Liu, F, Patient, R

“…In this review, we summarise our current knowledge of the cellular and genetic basis of ontogeny of the hematopoietic system in Xenopus and zebrafish embryos.…”

On the development of embryonic hematopoietic and endothelial cells in Xenopus. by Ciau-Uitz, A, Patient, R

Mitt contributes to the dendricity of melanoblasts in Xenopus laevis by Takahashi, K, Kumasaka, M, Sato, S, Yajima, I, Goding, C, Yamamoto, H

The replication capacity of intact mammalian nuclei in Xenopus egg extracts declines with quiescence, but the residual DNA synthesis is independent of Xenopus MCM proteins. by Sun, W, Hola, M, Pedley, K, Tada, S, Blow, J, Todorov, I, Kearsey, S, Brooks, R

“…Here we show that the replication capacity of nuclei from Swiss 3T3 cells, in Xenopus egg extracts, is not lost abruptly with the onset of quiescence, but instead declines gradually. …”

A role for GATA5 in Xenopus endoderm specification. by Weber, H, Symes, C, Walmsley, M, Rodaway, A, Patient, R

“…Here we show that GATA5, a zinc-finger transcription factor, is expressed in the yolk-rich vegetal cells of Xenopus embryos from the early gastrula stage onwards, when these cells become committed to form endoderm. …”

Mapping neurogenesis onset in the optic tectum of Xenopus laevis by Herrgen, L, Akerman, C

“…Our findings highlight the potential to use the optic tectum of Xenopus laevis as an accessible system for the study of the cell biology of neurogenesis. …”

A role for GATA factors in Xenopus gastrulation movements. by Fletcher, G, Jones, G, Patient, R, Snape, A

“…Gastrulation movements in Xenopus laevis are becoming increasingly well characterised, however the molecular mechanisms involved are less clear. …”

A genetic regulatory network for Xenopus mesendoderm formation. by Loose, M, Patient, R

“…We have constructed a genetic regulatory network (GRN) summarising the functional relationships between the transcription factors (TFs) and embryonic signals involved in Xenopus mesendoderm formation. It is supported by a relational database containing the experimental evidence and both are available in interactive form via the World Wide Web. …”

The origins and programming of adult and embryonic blood in xenopus and zebrafish. by Patient, R, Walmsley, M, Ciau-Uitz, A, Gering, M, Pinheiro, P, Patterson, L, Nastos, T, Gottgens, B, Green, T, Yamada, Y, Rabbitts, T

Tracking and programming early hematopoietic cells in Xenopus embryos. by Walmsley, M, Ciau-Uitz, A, Patient, R

“…The fates of lineage labeled hematopoietic precursor populations in Xenopus embryos are followed by use of in situ hybridization, looking for overlap between lineage labeled cells and in situ probes specific for known cell populations or states of differentiation. …”

cADPR stimulates SERCA activity in Xenopus oocytes. by Yamasaki-Mann, M, Demuro, A, Parker, I

“…Here, we explore the actions of cADPR in Xenopus oocytes, which lack RyRs. We examined the effects of cADPR on the sequestration of cytosolic Ca(2+) following Ca(2+) transients evoked by photoreleased inositol 1,4,5-trisphosphate (InsP(3)), and by Ca(2+) influx through expressed nicotinic acetylcholine receptors (nAChR) in the oocytes membrane. …”

PROGRAMMING BLOOD STEM CELLS IN XENOPUS AND ZEBRAFISH EMBRYOS by Patient, R

The organization of the tadpole and adult alpha globin genes of Xenopus laevis. by Patient, R, Banville, D, Brewer, A, Elkington, J, Greaves, D, Lloyd, M, Williams, J

Notch signalling in Xenopus laevis haematopoietic stem cell programming by Stephenson, RA

“…Here, the relatively slow development and the spatial separation of definitive haematopoiesis from primitive haematopoiesis in Xenopus laevis has been exploited to reveal the first defect of reduced notch signalling in the Xenopus DA.…”

5' structural motifs and Xenopus beta globin gene activation. by Brewer, A, Enver, T, Greaves, D, Allan, J, Patient, R

“…We have analysed the structure of the Xenopus beta globin gene 5' flanking region in erythroid and non-erythroid chromatin, in supercoiled plasmids and in minichromosomes assembled in HeLa cell transfections. …”

PROGRAMMING BLOOD STEM CELLS DURING XENOPUS AND ZEBRAFISH DEVELOPMENT by Patient, R

Optic synapses are found in diencephalic neuropils before development of the tectum in Xenopus. by Gaze, R, Wilson, M, Taylor, J

“…The position of the earliest optic synapses in Xenopus and the stage at which they developed were studied with the electron microscope after labelling of optic axons with horseradish peroxidase. …”