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Accuracy of radiological staging in identifying high-risk colon cancer patients suitable for neoadjuvant chemotherapy: a multicentre experience.
Published 2012“… AIM: A pilot study was undertaken to determine the accuracy of computed tomography (CT) staging in identifying patients with high-risk colon cancers who would be considered as candidates for a neoadjuvant therapy trial (FOxTROT) and those at low risk (T1/T2) who would be excluded. …”
Journal article -
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Ontological user profiling in recommender systems.
Published 2004“…Our two experimental systems, Quickstep and Foxtrot, create user profiles from unobtrusively monitored behaviour and relevance feedback, representing the profiles in terms of a research paper topic ontology. …”
Journal article -
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Stratifiers for oxaliplatin outcome in colorectal cancer
Published 2021“…To this aim, I have used multiomic data from two clinical trials of the S:CORT consortium (Focus and Foxtrot) and generated transcriptome from another clinical trial (Coin) for deep bioinformatic interrogation of the clinical question. …”
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In-depth clinical and biological exploration of DNA damage immune response as a biomarker for oxaliplatin use in colorectal cancer
Published 2020“…</p> <p><strong>Experimental Design:</strong> Samples and clinical data were assessed according to DDIR status from patients who received either 5-fluorouracil (5-FU) or 5FUFA (bolus and infusion 5-FU with folinic acid) plus oxaliplatin (FOLFOX) within the FOCUS trial (n = 361, stage IV), or neoadjuvant FOLFOX in the FOxTROT trial (n = 97, stage II/III). Whole transcriptome, mutation, and IHC data of these samples were used to interrogate the biology of DDIR in colorectal cancer.…”
Journal article