Lidocaine cytotoxicity to the zygapophysial joints in rabbits: changes in cell viability and proteoglycan metabolism in vitro. by Takeno, K, Kobayashi, S, Miyazaki, T, Shimada, S, Kubota, M, Meir, A, Urban, J, Baba, H

“….: To examine whether lidocaine cytotoxicity to chondrocytes has been implicated in the development of osteoarthritis of the zygapophysial joints. …”

Cost-effectiveness of a lidocaine plaster relative to pregabalin in the treatment of post-herpetic neuralgia in Scotland by Dakin, H, Nuijten, M, Poulsen, N, Liedgens, H

Cost-utility analysis evaluating lidocaine 5% medicated plaster relative to gabapentin for postherpetic neuralgia in Scotland by Dakin, H, Nuijten, M, Liedgens, H, Poulsen, N

Effects of prophylactic lidocaine in suspected acute myocardial infarction. An overview of results from the randomized, controlled trials. by MacMahon, S, Collins, R, Peto, R, Koster, R, Yusuf, S

“…During follow-up intervals of one to four hours in the trials of intramuscular lidocaine infusion (6961 patients) and 24 to 48 hours in the trials of intravenous lidocaine injection (2194 patients), a total of 103 cases of ventricular fibrillation and 137 deaths were recorded. …”

Cost-Effectiveness of a Lidocaine 5% Medicated Plaster Relative to Gabapentin for Postherpetic Neuralgia in the United Kingdom by Dakin, H, Nuijten, M, Liedgens, H, Nautrup, B

Costutility analysis evaluating the lidocaine 5% medicated plaster relative to gabapentin and pregabalin for postherpetic neuralgia in Germany by Liedgens, H, Hertel, N, Gabriel, A, Nuijten, M, Dakin, H, Sphrer, U, Poulsen Nautrup, B

Cost-effectiveness analysis of the lidocaine 5% medicated plaster relative to gabapentin and pregabalin for post-herpetic neuralgia in Germany by Liedgens, H, Hertel, N, Gabriel, A, Nuijten, M, Dakin, H, Spoehrer, U, Poulsen Nautrup, B

Block of voltage-operated sodium channels by 2,6-dimethylphenol, a structural analogue of lidocaine's aromatic tail. by Haeseler, G, Bufler, J, Merken, S, Dengler, R, Aronson, J, Leuwer, M

“…Its potency was comparable to the potency of lidocaine previously obtained with similar protocols by others. …”

Severe unilateral bronchospasm mimicking inadvertent endobronchial intubation: a complication of the use of a topical lidocaine Laryngojet injector. by Farmery, A

“…Severe unilateral bronchospasm was probably caused by topical lidocaine injected at the vocal cords and, inadvertently, into the left main bronchus with a Laryngojet device.…”

An improved model for the binding of lidocaine and structurally related local anaesthetics to fast-inactivated voltage-operated sodium channels, showing evidence of cooperativity. by Leuwer, M, Haeseler, G, Hecker, H, Bufler, J, Dengler, R, Aronson, J

“…1. The interaction of lidocaine-like local anaesthetics with voltage-operated sodium channels is traditionally assumed to be characterized by tighter binding of the drugs to depolarized channels. …”

Cost-effectiveness analysis of a lidocaine 5% medicated plaster compared with gabapentin and pregabalin for treating postherpetic neuralgia: a german perspective. by Liedgens, H, Hertel, N, Gabriel, A, Nuijten, M, Dakin, H, Mitchell, S, Nautrup, B

“…The lidocaine plaster dominated pregabalin 600 mg/day, being less costly and more effective. …”

Using Capsaicin Modified Multiwalled Carbon Nanotube Based Electrodes and p-Chloranil Modified Carbon Paste Electrodes for the Determination of Amines: Application to Benzocaine and Lidocaine by Kachoosangi, RT, Wildgoose, G, Compton, R

“…The applicability of p-chloranil modified carbon paste electrode was also examined with the additions of benzocaine and lidocaine which resulted in a decrease in the voltammetric signals of p-chloranil, which is again due to the formation of an adduct via a similar mechanism to that described above. © 2008 Wiley-VCH Verlag GmbH and Co. …”

Clinically important factors influencing the diagnostic measurement of pleural fluid pH and glucose. by Rahman, N, Mishra, E, Davies, H, Davies, R, Lee, Y

“…The effects of residual air, lidocaine, heparin, and delay in analysis (24 h) on pH and glucose measurement accuracy were assessed. …”

The role of nigral and thalamic output pathways in the expression of oral stereotypies induced by amphetamine injections into the striatum. by Canales, J, Gilmour, G, Iversen, S

“…We demonstrated that lidocaine-induced reversible inactivation of the SNr reduced amphetamine-induced stereotyped biting and gnawing behaviors, suggesting that the nigral output pathway plays a significant role in the expression of these behavioral responses. …”

Phenol derivatives accelerate inactivation kinetics in one inactivation-deficient mutant human skeletal muscle Na(+) channel. by Haeseler, G, Piepenbrink, A, Bufler, J, Dengler, R, Hecker, H, Aronson, J, Piepenbrock, S, Leuwer, M

“…Na(+) channel blockers like lidocaine and mexiletine, suggested for therapy of myotonia, do not reconstitute inactivation in channels with defective inactivation in vitro. …”

Comparison of intermediate vs subcutaneous cervical plexus block for carotid endarterectomy. by Ramachandran, S, Picton, P, Shanks, A, Dorje, P, Pandit, J

“…RESULTS: There was no statistically significant difference for median (range) lidocaine supplementation between the subcutaneous and intermediate groups 65 (20-170) mg vs. 85 (30-345) mg, respectively; P=0.31. …”

A comparison of superficial versus combined (superficial and deep) cervical plexus block for carotid endarterectomy: a prospective, randomized study. by Pandit, J, Bree, S, Dillon, P, Elcock, D, McLaren, I, Crider, B

“…Median supplemental lidocaine requirements were 100 mg (range 30-180 mg) in the superficial block group and 115 mg (range 30-250 mg) in the combined block group. …”

Expectations and positive emotional feelings accompany reductions in ongoing and evoked neuropathic pain following placebo interventions. by Petersen, G, Finnerup, N, Grosen, K, Pilegaard, H, Tracey, I, Benedetti, F, Price, D, Jensen, T, Vase, L

“…Eighteen patients with postthoracotomy neuropathic pain were exposed to placebo and nocebo manipulations, in which they received open and hidden administrations of pain-relieving (lidocaine) or pain-inducing (capsaicin) treatment controlled for the natural history of pain. …”

Evidenced-based local anaesthesia-is there a difference in practice between specialties in a major trauma centre? by Muscat, EPJ, Ali, S, Berner, JE

“…In scenario 1, 89% of ED participants chose lidocaine 1%, but only 38% of the plastic surgery team chose it. …”

Corticosteroid injection for shoulder pain: single-blind randomized pilot trial in primary care. by Holt, T, Mant, D, Carr, A, Gwilym, S, Beard, D, Toms, C, Yu, L, Rees, J

“…Eligible participants were randomized to receive either methylprednisolone acetate 40 mg with lidocaine 1% (total volume 1 ml), or lidocaine 1% alone (total volume 1 ml), injected into the subacromial space. …”