The embryonic mouse hindbrain as a qualitative and quantitative model for studying the molecular and cellular mechanisms of angiogenesis. by Fantin, A, Vieira, J, Plein, A, Maden, C, Ruhrberg, C

“…The hindbrain model also permits the visualization of ligand binding to blood vessels in situ and the analysis of blood vessel growth within a natural multicellular microenvironment in which endothelial cells (ECs) interact with non-ECs to refine the 3D organ architecture. The entire procedure, from embryo isolation to imaging and through to results analysis, takes approximately 4 d.…”

Ambiguity in the presentation of decellularized tissue composition: the need for standardized approaches by Bruyneel, A, Carr, C

“…Decellularization offers great potential to the field of tissue engineering, since this method gives rise to scaffold material with the native organ architecture by removing all cellular material and leaving much of the extra-cellular matrix (ECM) intact. …”

Stromal fibroblasts in tertiary lymphoid structures: A novel target in chronic inflammation by Barone, F, Gardner, DH, Nayar, S, Steinthal, N, Buckley, CD, Luther, SA

“…A complex and stereotyped series of events regulate fibroblast differentiation from embryonic life in SLOs to lymphoid organ architecture observed in adults. In contrast, TLS-associated fibroblasts differentiate from postnatal, locally activated mesenchyme, predominantly in settings of inflammation and persistent antigen presentation. …”