Snippets in surgical pathology by Cooper, K, Chetty, R

State of surgery in tropical Africa: a review. by Lavy, C, Sauven, K, Mkandawire, N, Charian, M, Gosselin, R, Ndihokubwayo, J, Parry, E

“…We discuss the enormous burden of surgical pathology (as far as it is known) and the access to and acceptability of surgery. …”

A fibrotic focus is a prognostic factor and a surrogate marker for hypoxia and (lymph)angiogenesis in breast cancer: review of the literature and proposal on the criteria of evalua... by Van den Eynden, G, Colpaert, C, Couvelard, A, Pezzella, F, Dirix, L, Vermeulen, P, Van Marck, E, Hasebe, T

“…Although modern surgical pathology uses different histopathological and molecular markers to assess the aggressiveness and predict the behaviour of malignant tumours, markers reflecting stromal cell behaviour and interactions between epithelial cells and stromal cells are scarce. …”

Insulinomas may present with normoglycemia after prolonged fasting but glucose-stimulated hypoglycemia by Kar, P, Price, P, Sawers, S, Bhattacharya, S, Reznek, R, Grossman, AB

“…Methods: We employed prolonged fasts and standard glucose tolerance tests, plus imaging studies and surgical pathology, in two patients with suspected insulinomas. …”

Precision immunoprofiling by image analysis and artificial intelligence by Koelzer, V, Sirinukunwattana, K, Rittscher, J, Mertz, K

“…We provide an outline to machine learning (ML) and artificial intelligence tools and illustrate fields of application in immune-oncology, such as pattern-recognition in large and complex datasets and deep learning approaches for survival analysis. Synergies of surgical pathology and computational analyses are expected to improve patient stratification in immuno-oncology. …”

Insulinomas may present with normoglycemia after prolonged fasting but glucose-stimulated hypoglycemia. by Kar, P, Price, P, Sawers, S, Bhattacharya, S, Reznek, R, Grossman, AB

“…METHODS: We employed prolonged fasts and standard glucose tolerance tests, plus imaging studies and surgical pathology, in two patients with suspected insulinomas. …”

Interobserver reliability in the histopathological diagnosis of cartilaginous tumors in patients with multiple osteochondromas. by de Andrea, C, Kroon, H, Wolterbeek, R, Romeo, S, Rosenberg, A, De Young, B, Liegl, B, Inwards, C, Hauben, E, McCarthy, E, Idoate, M, Athanasou, N, Jones, K, Hogendoorn, P, Bovée, J

“…The distinction between benign and malignant cartilaginous tumors located peripherally in the bone may be a challenging task in surgical pathology. The aim of this study was to investigate interobserver reliability in histological diagnosis of cartilaginous tumors in the setting of multiple osteochondromas and to evaluate possible histological parameters that could differentiate among osteochondroma, low- and high-grade secondary peripheral chondrosarcoma. …”

Infectious Diseases and Tropical Disease Pathology: SC16-1 rRNA SEQUENCING IN MOLECULAR MICROBIOLOGICAL DIAGNOSIS OF BACTERIAL INFECTIONS IN THE AUTOPSY SETTING. by Hart, J, Street, T, Wrightson, J, Moore, D, Scott, A, Crook, D, Turner, G

“…It has been used to identify bacteria in formalin fixed paraffin embedded (FFPE) surgical pathology specimens but its use has not been reported in autopsy diagnosis. …”

RFID analysis of the complexity of cellular pathology workflow—An opportunity for digital pathology by Browning, L, White, K, Siiankoski, D, Colling, R, Roskell, D, Fryer, E, Hemsworth, H, Roberts-Gant, S, Roelofsen, R, Rittscher, J, Verrill, C

“…RFID tracking of 1,173 surgical pathology cases and over 30 staff in an analog cellular pathology workflow illustrates the complexity of the physical movement of slides within the department, which impacts on case traceability within the system. …”

Robot-assisted radical cystectomy with intracorporeal neobladder diversion: The Karolinska experience. by Collins, J, Sooriakumaran, P, Sanchez-Salas, R, Ahonen, R, Nyberg, T, Wiklund, N, Hosseini, A

“…RESULTS: The mean age of our patients was 64 years (range 37-87). On surgical pathology 47% had pT1 or less disease, 27% had pT2, 16% had pT3 and 10% had pT4. …”

Evolution and oncological outcomes of a contemporary radical prostatectomy practice in a UK regional tertiary referral centre. by Gnanapragasam, V, Thurtle, D, Srinivasan, A, Volanis, D, George, A, Lophatananon, A, Stearn, S, Warren, A, Lamb, A, Shaw, G, Sharma, N, Thomas, B, Tran, M, Neal, D, Shah, N

“…The corresponding proportions for low-risk cases were 48.6% and 17.3%, respectively. Final surgical pathology showed an increase in tumour stage, Gleason grade, and nodal status over time. …”

Mature and immature extracranial teratomas in children: the UK Children's Cancer Study Group Experience. by Mann, JR, Gray, E, Thornton, C, Raafat, F, Robinson, K, Collins, G, Gornall, P, Huddart, SN, Hale, J, Oakhill, A

“…Carboplatin, etoposide, and bleomycin (JEB) were given for YST relapse, whereas relapsed MT and IT were treated at clinicians' discretion, usually surgically. Pathology was reviewed and treatments, outcome, and prognostic features assessed. …”