Impacts of COVID-19 on Tourism in Bar Harbor, Maine by Todd Gabe

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1208 Differential reliance on glucose oxidation by activated autoreactive B cells provides a novel target of therapeutic intervention by Peter E Lipsky, Derry C Roopenian, Amrie C Grammer, John J Wilson, Jian Wei, Andrea R Daamen, John D Sears, Elaine Bechtel, Colleen L Mayberry, Grace A Stafford, Chih-Hao Chang

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss by Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs

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New directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop by Maria A. Telpoukhovskaia, Thomas J. Murdy, Olivia J. Marola, Kevin Charland, Michael MacLean, Tain Luquez, Alexandra M. Lish, Sarah Neuner, Amy Dunn, Kristen D. Onos, Jesse Wiley, Derek Archer, Matthew J. Huentelman, Matthias Arnold, Vilas Menon, Alison Goate, Linda J. Van Eldik, Paul R. Territo, Gareth R. Howell, Gregory W. Carter, Kristen M. S. O'Connell, Catherine C. Kaczorowski, the 2022 JAX CADR Workshop

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Glucose oxidation-dependent survival of activated B cells provides a putative novel therapeutic target for lupus treatment by John J. Wilson, Jian Wei, Andrea R. Daamen, John D. Sears, Elaine Bechtel, Colleen L. Mayberry, Grace A. Stafford, Lesley Bechtold, Amrie C. Grammer, Peter E. Lipsky, Derry C. Roopenian, Chih-Hao Chang

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APOE ε4 and exercise interact in a sex‐specific manner to modulate dementia risk factors by Kate E. Foley, Cory A. Diemler, Amanda A. Hewes, Dylan T. Garceau, Michael Sasner, Gareth R. Howell

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Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of chronic levetiracetam treatment in 5XFAD mice: A MODEL‐AD preclinical testing core study by Kristen D. Onos, Sara K. Quinney, David R. Jones, Andrea R. Masters, Ravi Pandey, Kelly J. Keezer, Carla Biesdorf, Ingrid F. Metzger, Jill A. Meyers, Johnathon Peters, Scott C. Persohn, Brian P. McCarthy, Amanda A. Bedwell, Lucas L. Figueiredo, Zackary A. Cope, Michael Sasner, Gareth R. Howell, Harriet M. Williams, Adrian L. Oblak, Bruce T. Lamb, Gregory W. Carter, Stacey J. Sukoff Rizzo, Paul R. Territo

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Transfer learning‐trained convolutional neural networks identify novel MRI biomarkers of Alzheimer's disease progression by Yi Li, Annat Haber, Christoph Preuss, Cai John, Asli Uyar, Hongtian Stanley Yang, Benjamin A. Logsdon, Vivek Philip, R. Krishna Murthy Karuturi, Gregory W. Carter, The Alzheimer's Disease Neuroimaging Initiative

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First documented movement of a humpback whale between the Cape Verde Islands and West Greenland by Valerie Chosson, Virginie Wyss, Beatrice Jann, Frederick W. Wenzel, Guðjón Már Sigurðsson, Malene Simon, Rikke Guldborg Hansen, Lindsey S. Jones

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2102 Inhibition of glycolysis modifies distinctive wound and immune pathways across multiple tissue compartments associated with activated autoreactive B Cells by John Wilson, Chih-Hao Chang, Ann E Wells, Derry Roopenian, Gregory W Carter

Bridging the rodent to human translational gap: Marmosets as model systems for the study of Alzheimer's disease by Stacey J. Sukoff Rizzo, Gregg Homanics, David J. Schaeffer, Lauren Schaeffer, Jung Eun Park, Julia Oluoch, Tingting Zhang, Annat Haber, Nicholas T. Seyfried, Benedict Paten, Anna Greenwood, Takeshi Murai, Sang Ho Choi, Hasi Huhe, Julia Kofler, Peter L. Strick, Gregory W. Carter, Afonso C. Silva

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Mapping quantitative traits and strategies to find quantitative trait genes. by Flint, J

“…In 1999 a meeting took place at the Jackson Laboratory, a large mouse research centre in Bar Harbor, Maine, to consider the value of systematically collecting phenotypes on inbred strains of mice (Paigen and Eppig (2000) [1]). …”

Prophylactic evaluation of verubecestat on disease‐ and symptom‐modifying effects in 5XFAD mice by Adrian L. Oblak, Zackary A. Cope, Sara K. Quinney, Ravi S. Pandey, Carla Biesdorf, Andi R. Masters, Kristen D. Onos, Leslie Haynes, Kelly J. Keezer, Jill A. Meyer, Jonathan S. Peters, Scott A. Persohn, Amanda A. Bedwell, Kierra Eldridge, Rachael Speedy, Gabriela Little, Sean‐Paul Williams, Brenda Noarbe, Andre Obenaus, Michael Sasner, Gareth R. Howell, Gregory W. Carter, Harriet Williams, Bruce T. Lamb, Paul R. Territo, Stacey J. Sukoff Rizzo

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Open drug discovery in Alzheimer's disease by Alison D. Axtman, Paul E. Brennan, Tristan Frappier‐Brinton, Ranjita Betarbet, Gregory W. Carter, Haian Fu, Opher Gileadi, Anna K. Greenwood, Karina Leal, Frank M. Longo, Lara M. Mangravite, Aled M. Edwards, Allan I. Levey, The Emory‐Sage‐SGC TREAT‐AD Center

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Assessment of the Glycan-Binding Profile of Pseudomonas aeruginosa PAO1 by Hector Sanchez, George A. O’Toole, Brent Berwin

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Rat allele variation determines susceptibility to AngII-induced renal damage by Jelena Kamilic, Inge Hamming, A Titia Lely, Ron Korstanje, Ute Schulze, Wilfred J Poppinga, Anthony J Turner, Nicola E Clarke, Harry van Goor, Gerjan J Navis

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Clathrin light chain‐conjugated drug delivery for cancer by Sungwook Jung, Liwei Jiang, Jing Zhao, Leonard D. Shultz, Dale L. Greiner, Munhyung Bae, Xiaofei Li, Farideh Ordikhani, Rui Kuai, John Joseph, Vivek Kasinath, David R. Elmaleh, Reza Abdi

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Distinct roles of estrone and estradiol in endothelial colony‐forming cells by Alicia Ivory, Andrew S. Greene

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Induction of Stress-Induced Renal Cellular Senescence In Vitro: Impact of Mouse Strain Genetic Diversity by Chieh Ming Liao, Vera Christine Wulfmeyer, Maxine Swallow, Christine Susanne Falk, Hermann Haller, Ron Korstanje, Anette Melk, Roland Schmitt

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Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages by Taylor A. Stepien, Larissa A. Singletary, Fermin E. Guerra, Joyce E. Karlinsey, Stephen J. Libby, Sarah L. Jaslow, Margaret R. Gaggioli, Kyle D. Gibbs, Dennis C. Ko, Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz, Ferric C. Fang

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