Novel insights from our special issue on maternal factors during pregnancy that influence maternal, fetal and childhood outcomes by Stephen Tong, Katrien Benhalima, Louis Muglia, Susan Ozanne

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Advances in Biomaterials for Drug Delivery by Fenton, Owen Shea, Olafson, Katy, Pillai, Padmini S, Mitchell, Michael J., Langer, Robert S

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Review on new approach methods to gain insight into the feto-maternal interface physiology by Ramkumar Menon, Louis J. Muglia, Louis J. Muglia, Lisa Hara Levin

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Maternal factors during pregnancy influencing maternal, fetal, and childhood outcomes by Louis J. Muglia, Katrien Benhalima, Stephen Tong, Susan Ozanne

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Current CRISPR gene drive systems are likely to be highly invasive in wild populations by Noble, Charleston, Adlam, Ben, Church, George M, Esvelt, Kevin, Nowak, Martin A

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Structure of the Mitochondrial Aminolevulinic Acid Synthase, a Key Heme Biosynthetic Enzyme by Brown, Breann L., Kardon, Julia R., Sauer, Robert T, Baker, Tania

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Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy by Guimarães, Pedro P.G., Gaglione, Stephanie, Sewastianik, Tomasz, Carrasco, Ruben D., Langer, Robert S, Mitchell, Michael J.

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MetaMerge: scaling up genome-scale metabolic reconstructions, with application to Mycobacterium tuberculosis by Chindelevitch, Leonid, Stanley, Sarah, Hung, Deborah T., Regev, Aviv, Berger Leighton, Bonnie

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Y MAP: a pipeline for visualization of copy number variation and loss of heterozygosity in eukaryotic pathogens by Abbey, Darren A., Funt, Jason, Lurie-Weinberger, Mor N., Thompson, Dawn A., Regev, Aviv, Myers, Chad L., Berman, Judith

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Estimating prevalence of human traits among populations from polygenic risk scores by Britney E. Graham, Brian Plotkin, Louis Muglia, Jason H. Moore, Scott M. Williams

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Massively parallel screening of synthetic microbial communities by Kehe, Jared Scott, Kulesa, Anthony Benjamin, Ortiz, Anthony, Gore, Jeff, Blainey, Paul C

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Daisy-chain gene drives for the alteration of local populations by Noble, Charleston, Min, John, Olejarz, Jason, Buchthal, Joanna, Chavez, Alejandro, Smidler, Andrea L., DeBenedictis, Erika A., Church, George M., Nowak, Martin A., Esvelt, Kevin Michael

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Networks of imperial tropical medicine: ideas and practices of health and hygiene in the British Empire, 1895-1914 by Johnson, R, Ryan M Johnson

“…To accomplish this, the first part of the thesis considers largely ignored popular networks of ITM, including the 1900 London Livingstone Exhibition; guidebooks and manuals for tropical travel, health and hygiene; and commodities such as Burroughs Wellcome & Co.’s (BWC) Tabloid brand medicine chests and tropical clothing. …”

Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprim by Iris K. Lee, Daniel A. Jacome, Joshua K. Cho, Vincent Tu, Anthony J. Young, Tiffany Dominguez, Justin D. Northrup, Jean M. Etersque, Hsiaoju S. Lee, Andrew Ruff, Ouniol Aklilu, Kyle Bittinger, Laurel J. Glaser, Daniel Dorgan, Denis Hadjiliadis, Rahul M. Kohli, Robert H. Mach, David A. Mankoff, Robert K. Doot, Mark A. Sellmyer

“…Clinical imaging of patients with [11C]-TMP demonstrated focal radiotracer uptake in areas of infectious lesions.CONCLUSION This work highlights an approach to imaging bacterial infection in patients, which could affect our understanding of bacterial pathogenesis as well as our ability to better diagnose infections and monitor response to therapy.TRIAL REGISTRATION ClinicalTrials.gov NCT03424525.FUNDING Institute for Translational Medicine and Therapeutics, Burroughs Wellcome Fund, NIH Office of the Director Early Independence Award (DP5-OD26386), and University of Pennsylvania NIH T32 Radiology Research Training Grant (5T32EB004311-12).…”
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Addressing the challenges of implementing evidence-based prioritisation in global health by Amanda McClelland, Richard Garfield, Louis J Muglia, David T S Hayman, Kashef Ijaz, Chris Atim, Rosemary K Barraclough, Victoria McGovern, Muhammed O. Afolabi, Alhaji U N'Jai, Jennyfer R. Ambe, Beverley Paterson, Jennifer Lasley, Qadeer Ahsan, Kendra Chittenden, Alexandra L. Phelan, Abigail Lopez Rivera

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Dense phenotyping from electronic health records enables machine learning-based prediction of preterm birth by Abin Abraham, Brian Le, Idit Kosti, Peter Straub, Digna R. Velez-Edwards, Lea K. Davis, J. M. Newton, Louis J. Muglia, Antonis Rokas, Cosmin A. Bejan, Marina Sirota, John A. Capra

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Engineering and physical sciences in oncology: challenges and opportunities by Mitchell, Michael J, Jain, Rakesh K., Langer, Robert S

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Clustering and Symbolic Analysis of Cardiovascular Signals: Discovery and Visualization of Medically Relevant Patterns in Long-Term Data Using Limited Prior Knowledge by Syed, Zeeshan, Guttag, John V., Stultz, Collin M.

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A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking by Daniels, Rachel F., Mahesh, Nira, Rosen, David, Angelino, Elaine, Neafsey, Daniel E., Park, Daniel J., Sabeti, Pardis C., Wiegand, Roger C., Volkman, Sarah K., Milner, Danny A., Wirth, Dyann F.

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An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation by Kini, Mitali, Mattaini, Katherine Ruth, Davidson, Shawn Michael, Fiske, Brian Prescott, Vander Heiden, Matthew G., Brignole, Edward J, Drennan, Catherine L

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