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Nascent Adhesion Clustering: Integrin-Integrin and Integrin-Substrate Interactions
Published 2022-01-01Subjects: Get full text
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Regulation of Dynamic Cell Adhesion by Integrin-Integrin Crosstalk
Published 2022-05-01Subjects: “…integrin…”
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The tail of integrin activation.
Published 2011“…Integrins are essential adhesion receptors found on the surfaces of all metazoan cells. …”
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Integrin Inhibitors in Prostate Cancer
Published 2018-02-01“…Currently, several compounds have proven to target specific integrins and their subunits in PCa cells. In this article, we review the role of integrins inhibitors in PCa and their potential as therapeutic targets for PCa treatments. …”
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Integrin Targeted Imaging and Therapy
Published 2011-01-01“…<p>This theme issue provides an overview on the biology and pathology of various integrins as well as in-depth discussion on the use of integrin as targeting molecules for molecular imaging and molecular therapy.…”
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Integrin Conformational Dynamics and Mechanotransduction
Published 2022-11-01Subjects: “…integrin…”
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Integrin structure, activation, and interactions.
Published 2011“…Integrins are large, membrane-spanning, heterodimeric proteins that are essential for a metazoan existence. …”
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Structural studies of integrin activation
Published 2009“…<p>Fundamental to cell adhesion and migration, integrins are large heterodimeric membrane proteins that link the extracellular matrix to the actin cytoskeleton. …”
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Beta integrin tyrosine phosphorylation is a conserved mechanism for regulating talin-induced integrin activation.
Published 2009“…Integrins are large membrane-spanning receptors fundamental to cell adhesion and migration. …”
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A membrane-distal segment of the integrin alpha IIb cytoplasmic domain regulates integrin activation.
Published 2001“…Previous evidence suggests that interactions between integrin cytoplasmic domains regulate integrin activation. …”
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Humanized β2 Integrin-Expressing Hoxb8 Cells Serve as Model to Study Integrin Activation
Published 2022-05-01Subjects: “…β2 integrin activation…”
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An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding.
Published 2008“…Integrins play a fundamental role in cell migration and adhesion; knowledge of how they are regulated and controlled is vital for understanding these processes. …”
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A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion.
Published 2008“…Integrin-linked kinase (ILK) has been implicated in the regulation of a range of fundamental biological processes such as cell survival, growth, differentiation, and adhesion. …”
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Alpha4 integrin binding interfaces on VCAM-1 and MAdCAM-1....
Published 1997“…Integrins are a family of heterodimeric adhesion receptors that mediate cellular interactions with a range of matrix components and cell surface proteins. …”
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Integrins as Therapeutic Targets: Successes and Cancers
Published 2017-08-01Subjects: “…integrin…”
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Integrin Regulation of CAF Differentiation and Function
Published 2019-05-01Subjects: “…integrin…”
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