-
1
-
2
From chemical mutagenesis to post-expression mutagenesis: A 50 year odyssey.
Published 2016“…Site-directed (gene) mutagenesis has been the most useful method available for the conversion of one amino acid residue of a given protein into another. …”
Journal article -
3
Structural basis of DNA mutagenesis
Published 1992“…Finally, an important study of a dodecamer containing a sequence corresponding to a hotspot for frameshift mutagenesis is described. This structure contains a novel type of groove backbone interaction and novel base mispairing which suggest a molecular model for frameshift substitution mutagenesis.…”
Journal article -
4
APOBEC Mutagenesis in Cancer Development and Susceptibility
Published 2024-01-01Subjects: Get full text
Article -
5
Long-distance effects of insertional mutagenesis.
Published 2011-01-01“…Most common systems of genetic engineering of mammalian cells are associated with insertional mutagenesis of the modified cells. Insertional mutagenesis is also a popular approach to generate random alterations for gene discovery projects. …”
Get full text
Article -
6
High-throughput site-directed mutagenesis
Published 2019“…Protein engineering is almost exclusively performed using site-directed mutagenesis (SDM) as this provides targeted modification of specific amino acids, as well as the option of rewriting the native sequence to include or exclude certain regions. …”
Book section -
7
"Site-selected" transposon mutagenesis of Drosophila.
Published 1990“…There are obvious implications of this technique for the mutagenesis of other organisms.…”
Journal article -
8
High throughput mutagenesis and screening for yeast engineering
Published 2022-12-01Subjects: Get full text
Article -
9
Development of a Model Mutagenesis System for Snapdragon
Published 2020-09-01Subjects: “…JI2 mutagenesis system…”
Get full text
Article -
10
Atomic mutagenesis in ion channels with engineered stoichiometry
Published 2016-10-01Subjects: “…atomic mutagenesis…”
Get full text
Article -
11
Pathways and signatures of mutagenesis at targeted DNA nicks.
Published 2021-04-01“…Nicks are the most frequent form of DNA damage and a potential source of mutagenesis in human cells. By deep sequencing, we have identified factors and pathways that promote and limit mutagenic repair at a targeted nick in human cells. …”
Get full text
Article -
12
Silver nanoparticles elevate mutagenesis of eukaryotic genomes
Published 2023-01-01Get full text
Article -
13
Site directed mutagenesis of alkyl hydroperoxide reductase.
Published 2009“…This research was designed to investigate the binding site of nicotinamide adenine dinucleotide (NADH) on alkyl hydroperoxide reductase subunit F (AhpF) of Salmonella typhimurium by using site directed mutagenesis. The postulated binding site was suggested by using molecular mechanics Poisson–Boltzmann surface area (MM/PBSA) approach. …”
Get full text
Final Year Project (FYP) -
14
-
15
-
16
Expression and mutagenesis of bacteriorhodopsin an integral membrane protein
Published 1998“…With sufficient protein, site directed mutagenesis is performed to mutate three proline residues present in the membranous region of bacteriorhodopsin to alanine. …”
Thesis -
17
Mutagenesis Of Microbial Transglutaminase For QTAG-KTAG Conjugation
Published 2018“…However, mTGase has low substrate specificity due to its wide active site cleft which impeding its diverse applications in biotechnological use. Therefore, mutagenesis of mTGase to obtain substrate specific enzyme is highly desirable for site-specific conjugations.…”
Get full text
Thesis -
18
Full-Spectrum Targeted Mutagenesis in Plant and Animal Cells
Published 2021-01-01Subjects: Get full text
Article -
19
Deconstruction of the Ras switching cycle through saturation mutagenesis
Published 2017-07-01Get full text
Article -
20
The Effects of Vitamin C on Oxidative DNA Damage and Mutagenesis
Published 2006-01-01“…DNA damage induced by reactive oxygen species is involved in mutagenesis and generation of mutation-related diseases, including cancer. …”
Get full text
Article