Showing 1 - 20 results of 4,354 for search '"mutagenesis"', query time: 0.09s Refine Results
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    From chemical mutagenesis to post-expression mutagenesis: A 50 year odyssey. by Wright, T, Vallée, M, Davis, B

    Published 2016
    “…Site-directed (gene) mutagenesis has been the most useful method available for the conversion of one amino acid residue of a given protein into another. …”
    Journal article
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    Structural basis of DNA mutagenesis by Brown, T, Kennard, O

    Published 1992
    “…Finally, an important study of a dodecamer containing a sequence corresponding to a hotspot for frameshift mutagenesis is described. This structure contains a novel type of groove backbone interaction and novel base mispairing which suggest a molecular model for frameshift substitution mutagenesis.…”
    Journal article
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    Long-distance effects of insertional mutagenesis. by Ruchi Singhal, Xiaotao Deng, Alex A Chenchik, Eugene S Kandel

    Published 2011-01-01
    “…Most common systems of genetic engineering of mammalian cells are associated with insertional mutagenesis of the modified cells. Insertional mutagenesis is also a popular approach to generate random alterations for gene discovery projects. …”
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    Article
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    High-throughput site-directed mutagenesis by Strain-Damerell, C, Burgess-Brown, NA

    Published 2019
    “…Protein engineering is almost exclusively performed using site-directed mutagenesis (SDM) as this provides targeted modification of specific amino acids, as well as the option of rewriting the native sequence to include or exclude certain regions. …”
    Book section
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    "Site-selected" transposon mutagenesis of Drosophila. by Kaiser, K, Goodwin, S

    Published 1990
    “…There are obvious implications of this technique for the mutagenesis of other organisms.…”
    Journal article
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    Pathways and signatures of mutagenesis at targeted DNA nicks. by Yinbo Zhang, Luther Davis, Nancy Maizels

    Published 2021-04-01
    “…Nicks are the most frequent form of DNA damage and a potential source of mutagenesis in human cells. By deep sequencing, we have identified factors and pathways that promote and limit mutagenic repair at a targeted nick in human cells. …”
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    Article
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    Site directed mutagenesis of alkyl hydroperoxide reductase. by Tee, Chiu Seng.

    Published 2009
    “…This research was designed to investigate the binding site of nicotinamide adenine dinucleotide (NADH) on alkyl hydroperoxide reductase subunit F (AhpF) of Salmonella typhimurium by using site directed mutagenesis. The postulated binding site was suggested by using molecular mechanics Poisson–Boltzmann surface area (MM/PBSA) approach. …”
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    Final Year Project (FYP)
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    Expression and mutagenesis of bacteriorhodopsin an integral membrane protein by Sidhu, I, Sidhu, Inderjit Kaur

    Published 1998
    “…With sufficient protein, site directed mutagenesis is performed to mutate three proline residues present in the membranous region of bacteriorhodopsin to alanine. …”
    Thesis
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    Mutagenesis Of Microbial Transglutaminase For QTAG-KTAG Conjugation by Chan, Soo Khim

    Published 2018
    “…However, mTGase has low substrate specificity due to its wide active site cleft which impeding its diverse applications in biotechnological use. Therefore, mutagenesis of mTGase to obtain substrate specific enzyme is highly desirable for site-specific conjugations.…”
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    Thesis
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    The Effects of Vitamin C on Oxidative DNA Damage and Mutagenesis by Jasna Stanojević, Branka Vuković-Gačić, Draga Simić, Jelena Knežević-Vukčević, Biljana Nikolić

    Published 2006-01-01
    “…DNA damage induced by reactive oxygen species is involved in mutagenesis and generation of mutation-related diseases, including cancer. …”
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    Article