The role of integrins αv in the pathogenesis of oral squamous cell carcinoma by G. M. Tuguzbaeva, V. N. Pavlov

“…It is known that the integrin family receptors are crucial for regenerative and reparative functions of the normal epithelium. …”
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Relationship of the integrin profile of the primary tumor to metastasis to regional lymph nodes in breast cancer by Marina V. Zavyalova, Gleb A. Kuznecov, Evgeniya S. Grigoryeva, Liubov A. Tashireva, Dmitry S. Pismenny, Vladimir M. Perelmuter

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GLYCOPROTEIN INTEGRIN ALPHA POLYMORPHISM AND ACUTE CEREBROVASCULAR EVENTS IN THE FAMILIES OF PATIENTS WITH ATRIAL FIBRILLATION by N. V. Aksyutina, S. Yu. Nikulina, V. A. Shulman, B. V. Nazarov, B. V. Maksimov, A. P. Bezruk, A. I. Balog, E. E. Poplavskaya, A. V. Bespalov, M. Yu. Kotlovskyi, A. A. Chernova

“…To assess the associations between the polymorphism of the glycoprotein integrin alpha (I…”
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Experimental study of the pharmacokinetics of monoclonal antibodies to α4β1-integrin in guinea pigs by B. N. Krapivin, O. V. Goncharova, E. L. Morozova

Subjects: “…monoclonal antibodies to α4β1-integrin…”
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Is there a dependence between expression of integrin receptors by peripheral blood immune cells and duration of tuberculous granuloma existence in the patients? by О. V. Berdyugina

“…Cell fusion during the formation of pulmonary tuberculous granuloma involves a large number of adhesive events. Importance of α1β1 integrin has been shown for the granuloma integrity during the chronic phase of infection. …”
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MORPHOLOGICAL AND EXPRESSION FEATURES OF DUCTAL PANCREATIC ADENOCARCINOMA by Yu. Yu. Rakina, M. V. Zavyalova, N. V. Krakhmal, A. P. Koshel, S. G. Afanasyev, S. V. Vtorushin

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Vedolizumab for inflammatory bowel diseasesI by Igor L. Khalif, M. V. Shapina

“…The vedolizumab is anti-α4β7-integrin humanized class IgG1 antibodies which suppresses migration of leukocytes in intestinal tissue, interfering thereby with development of pathologic inflammation. …”
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EXPRESSION OF SURFACE MARKERS ON CD4+T-LYMPHOCYTES IN NORMAL PREGNANCY AND PRE-ECLAMPSIA by V. A. Mikhailova, Y. S. Onokhina, O. M. Ovchinnikova, M. I. Mirashvili, M. S. Zainulina, S. A. Sel’kov, D. I. Sokolov

“…The amounts of CD4+T-lymphocytes expressing CD184, CD119, CD192, CD197, β7 integrin, CD29, CD49d, CD11b were elevated in healthy pregnant women, as compared with non-pregnant women. …”
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Vedolizumab in the treatment of inflammatory bowel diseases: whom and how? by A. O. Golovenko, O. V. Golovenko

“…The article is devoted to the use of vedolizumab, an α4β7 integrin antagonist, in the treatment of inflammatory bowel diseases (ulcerative colitis and Crohn’s disease). …”
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Microdomain forming proteins in oncogenesis by I. B. Zborovskaya, S. A. Galetskiy, A. V. Komel’kov

“…Involvement of the different lipid rafts is necessary in many situations such as binding of growth factors with their receptors, integrin regulation, cytoskeleton and extracellular matrix rearrangements, vesicular transport, etc. …”
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Molecular Mechanisms of Ebola Virus Entry into Permissive Cells by T. E. Sizikova, V. N. Lebedev, V. B. Pantyukhov, S. V. Borisevich

“…The main host-cell factors, involved in filovirus entry, are: attachment factors (cell lectins and human T-cell mucin 1 (TIM-1)), signaling factors (tyrosinkinase receptors and α5β1-integrin), and endolisosomal host-cell factors (cathepsins B and L and Niemann-Pick C1 protein. …”
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Biodegradable small-diameter vascular graft: types of modification with bioactive molecules and RGD peptides by E. A. Senokosova, E. O. Krivkina, L. V. Antonova, L. S. Barbarash

“…This sequence is present in most extracellular matrix proteins and has a tropism for integrin receptors of endothelial cells. Many studies have shown that imitation of the functional activity of the natural extracellular matrix can promote spontaneous endothelization of the inner surface of a vascular graft. …”
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Real clinical practice of complicated Crohn’s disease treatment with ustekinumab: clinical case presentation by P. A. Makarchuk, E. Yu. Lomakina, E. A. Belousova, S. E. Dubrova

“…In the cases of steroid refractory CD treatment options include biologics of different classes: tumour necrosis factor alfa - inhibitors (iTNF-α), α4β7 integrin inhibitor (vedolizumab), IL-12/23 inhibitor (ustekinumab). …”
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Primary immunodeficiency in a patient with Kabuki syndrome by I. S. Dolgopolov, L. Yu. Grivtsova, O. K. Ustinova, M. Yu. Rykov

“…In addition, no expression of integrin-beta (CD18) on neutrophils revealed.Conclusion. …”
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The role of platelets in inflammation and immunity by S. P. Sviridova, O. V. Somonova, Sh. R. Kashiya, O. A. Obukhova, A. V. Sotnikov

“…The role of platelets as a key component of the innate immune system was presented, which is confirmed by the presence of Tolllike receptors (TLR) and glycoproteins, such as integrin αIIbβ3, glycoprotein Ib-IX and FcγRIIa, involved in interaction with bacterial cells. …”
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INFLUENCE OF SOLUBLE PLACENTAL TISSUE-DERIVED MOLECULES UPON EXPRESSION OF ADHESION MOLECULES BY EA.HY926 ENDOTHELIAL CELLS by O. I. Stepanova, T. U. Lvova, E. N. Purbeeva, M. I. Mirashvili, M. S. Zainulina, S. A. Selkov, D. I. Sokolov

“…Placental tissue supernatants produced by the first- and third-trimester placental tissue from normal pregnancy, as well as from women with gestosis, induced higher expression of CD31, CD9, CD62E, CD62P, CD34, CD54, CD51/61, CD49d  and  integrin  β7  expression  by  endothelial  cells,  as  compared  with  their  baseline  levels.  …”
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NUCLEAR MEDICINE TECHNIQUES FOR IN VIVO ANIMAL IMAGING by Y. A. Finogenova, A. A. Lipengolts, A. V. Smirnova, E. Y. Grigorieva

“…Besides traditional radiopharmaceuticals, such as [18F]-FDG and [99mTc]-MDP, the new radiolabeled tracers, such as [99mTc]-3PRGD2, [ 99mTc]-HisoDGR targeted to integrin, [18F]- tetrafluoroborate, labeled antibodies and others have been used for the noninvasive detection of tumors and for monitoring their response to treatment in mice and rats. 111In and 89Zr –labeled monoclonal antibodies are used to evaluate the expression level of many receptors such as EGFR, HER-2 and others in different tumors. …”
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Pannus growth regulators as potential targets for biological therapy in rheumatoid arthritis by A. S. Mikhaylova, O. M. Lesnyak

“…It is  shown that the most promising targets for biological therapy may be FLS adhesion molecules, such as transmembrane receptor cadherin  11, integrins α5/β1, and VCAM1, ICAM1, which actively participate in the attachment of FLSs to the cartilage surface and activate their production of cytokines, growth factors and aggression factors.…”
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Effect of dexamethasone therapy on factors of adhesiveness and coagulation in acute lower limb ischemia by I. D. Magamedov, L. P. Pivovarova, S. A. Platonov, S. V. Ordynets, S. P. Nokhrin, O. B. Ariskina, I. V. Osipova, K. N. Fomin, A. B. Kurilov, A. I. Tomchenko, V. N. Zhigalo, S. L. Potskhor-ogly, L. V. Kolichenko, O. I. Dyko, T. V. Kopylova, T. A. Isaev

“…The number of lymphocytes expressing adhesion molecules ICAM-1 (CD54+) and integrins (CD18+) was counted using the immunocytochemical method. …”
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CHARACTERISTICS OF CELLULAR AND SERUM COMPONENTS OF MUCO-SALIVARY IMMUNE COMPARTMENT IN MATURE, AGED, AND SENESCENT PERSONS by E. D. Altman, A. V. Zurochka, S. N. Teplova, E. V. Davydova, D. Sh. Altman

“…Among specific markers determining intensity of MALT-associated aging, a decreased percentage of viable immune cells (below 40%), along with the prevalence of the neutrophilic granulocytes in the salivary secretions (over 98%) (with increased expression of β2-integrins); decreased counts of mononuclear cells, i.e., mononuclear cells with low expression of CD11β adhesion molecules, B-lymhocytes, and Th-lymphocytes have been revealed. …”
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