«Propofol infusion syndrome» - case in a child of 10 years by S. S. Postnikov, M. N. Kostyleva, G. P. Bryusov

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Instantaneous EEG signal analysis based on empirical mode decomposition applied to burst-suppression in propofol anaesthesia by Sobolova, G, Fabus, MS, Fischer, M, Drobny, M, Drobna-Saniova, B

“…In this study we applied EMD to analyse burst-suppression (BS) in the human EEG during induction of general anaesthesia (GA) with propofol. BS is a state characterised by cyclic changes between significant depression of brain activity and hyper-active bursts with variable duration, amplitude, and waveform shape. …”

A NEW APPROACH TO SOLVING GENERAL ANAESTHESIA INDIVIDUALIZATION PROBLEM DURING SURGICAL OPERATIONS WITH CARDIOPULMONARY BYPASS by V. M. Magilevets, V. V. Firsov, V. M. Zaiko, I. A. Kozlov

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Obtaining substituted phenol derivatives with potential antimicrobial activity by V. A. Sokhraneva, D. A. Yusupova, V. S. Boriskin, N. V. Groza

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INHALATION SEDATION IN THOSE WITH SEPSIS-ASSOCIATED DELIRIUM by N. A. Rezepov, O. N. Ulitkina, Yu. V. Skripkin, T. S. Zabelina, V. V. Likhvantsev

“…Inhalation sedation reduced the delirium duration compared to intravenous use of propofol: delirium was fully managed on the 5th day in the group where sevorane was used [4; 7], while in the group where propofol was used delirium lasted for 7 days [6; 8] (p = 0.03). …”
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The impact of general anesthesia on methionine metabolism during cardiopulmonary bypass by Yu. S. Polushin, T. F. Subbotina, N. S. Molchan, A. A. Zhloba

“…The most significant consumption of methionine was noted when propofol was used. In the same group, the exocytic release of homocysteine into the blood and the formation of cysteine were significantly lower. …”
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FACTORS DEFINING CLINICAL OUTCOMES IN THE PATIENTS WITH SEVERE CONCOMITANT TRAUMA COMPLICATED BY DELIRIUM by F. F. Bershadskiy, O. N. Ulitkina, Yu. V. Skripkin, O. A. Grebenchikov, V. V. Likhvantsev

“…The use of dexmedetomidine for management of delirium resulted in the reduction of multiple organ dysfunctions versus propofol. The severity of trauma was associated with chances to develop a continuous cognitive dysfunction and lethal outcome. …”
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Experimental justification of the dexmedetomidine admini stration for medical support in a photodynamic therapy by L. V. Galebskaya, A. I. Akopov, E. B. Miroshnikova, I. L. Solovtsova, M. G. Kovalev, V. Rochanorun

“…The influence of anesthetics, namelydexmeditomidine (Dexdor®, «Orion PharmaLtd.») and propofol (Propofol®, «Fresenius Kabi Ltd.»), on a photoinduced lysis of human red blood cells was under study in conditions close to the physiological ones (pH 7,4, 37 oC) using radachlorin (Radachlorin® «Radapharma Ltd.») as a photosensitizer. …”
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Dynamics of indices of cerebral oximetry in various procedures of general anesthesia on stages of transduodenal endoscopic operative interventions in patients, suffering obturation... by S. V. Меlnyk

“…In patients of Group I the intravenous general anesthesia with propofol and fentanyl in conditions of a secured spontaneous respiration with the oxygen inhalation was applied; in patients of Group II - intravenous general anesthesia, using propofol, fentanyl and atracurium besylate in conditions of a controlled mechanical ventilation (СМV) via a standard endotracheal tube; in patients of Group III - a deep analgosedation, using propofol and fentanyl in conditions of supportive pulmonary ventilation in a regime of synchronized intermittent mandatory ventilation (SIMV) via gastrolaryngeal tube. …”
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Increase of Cardioprotective Effectiveness of Remote Ischemic Preconditioning during Cardiac Surgery by A. M. Radovskiy, A. E. Bautin, L. I. Karpova, A. O. Marichev, I. Yu. Ivanov, V. L. Etin, E. Yu. Vasilyeva, М. L. Ivanova, E. V. Batalina, V. K. Grebennik, D. A. Laletin

“…Patients were divided in 5 groups: Group 1 ‒ Sevoflurane control (ContrSevo), RIPC was not used, sevoflurane anesthesia (n = 24); Group 2 ‒ RIPC1 sevoflurane (RIP1Sevo), RIPC with ischemia-reperfusion of one lower limb, sevoflurane anesthesia (n = 26); Group 3 ‒ RIPC2 sevoflurane (RIP2Sevo), RIPC with ischemia-reperfusion of two lower limbs, anesthesia sevoflurane (n = 23); Group 4 ‒ Propofol control (ContrProp), RIPC was not used, propofol anesthesia (n = 22); Group 5 ‒ RIPC2 propofol (RIP2Prop), RIPC with ischemia-reperfusion of two lower limbs, propofol anesthesia (n = 24). …”
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THE PROTECTIVE PROPERTIES OF SEVOFLURANE AT ISCHEMIA-REPERFUSION INJURY OF TRANSPLANTED CADAVERIC KIDNEY by M. Sh. Khubutia, S. V. Zhuravel, I. I. Utkina, A. V. Pinchuk, N. K. Kuznetsova

“…Sevoflurane had more effective renoprotective properties than propofol.…”
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IMPACT OF ANESTHESIA METHODS ON CENTRAL HEMODYNAMICS AND CEREBRAL BLOOD FLOW DURING CAROTID ENDARTERECTOMY by M. I. Neymark, V. V. Shmelev, A. A. Shaydurov, B. A. Shadymov

“…The total intravenous anesthesia (sedation with propofol, n = 60) and general combined anesthesia (sedation with sevoflurane, n = 60) were compared in 130 patients undergoing carotid endarterectomy. …”
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THE PROBLEMS OF COOPERATION BETWEEN ANAESTHESIOLOGY , NEUROSURGERY AND FUNCTIONAL DIAGNOSTICS IN CASE OF EPILEPSY SURGERY by A. S. Shershever, G. V. Cherkasov, S. A. Lavrova

“…The types of anaesthesia care for patients with drug-resistant epilepsy during stereotaxic operations for epilepsy pathways have been analyzed.Objective: to assess the adequacy of anesthesia and optimal values of EEG for total intravenous anesthesia based of Propofol, Midazolam and Fentanyl in stereotaxic operations for epilepsy.Materials and Methods. …”
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HEMODYNAMIC AND GAS EXCHANGE RESPONSE IN CHILDREN WITH CNS DISORDERS DURING PROCEDURAL SEDATION UNDERGOING COMPUTED TOMOGRAPHY by R. V. Zhdanov, E. V. Grigoriev

“…Hypercapnia and reduced saturation were documented in the propofol group, which were the consequences of hypoventilation and they required the respiratory support in the form of oxygen insufflation through the face mask in 46.7% of cases or artificial pulmonary ventilation (30% of cases). …”
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IMPACT OF INTRA-OPERATIVE SEDATION WITH SPINAL ANESTHESIA DURING UTERUS AMPUTATION ON COGNITIVE FUNCTIONS IN THE POST-OPERATIVE PERIOD by T. I. Akimenko, V. M. Zhenilo, E. A. Lebedeva, S. V. Zdiruk, Yu. S. Aleksandrovich

“…Dexmedetomidine (0.5-1.2 mcg/kg per 1 hour) was used in the patients from Group 1 (28 women), and propofol (2-10 mg/kg per 1 hour) was used in Group 2 (37 women). …”
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The impact of anesthesia method on the severity of oxidative stress during coronary artery bypass grafting with cardiopulmonary bypass by O. N. Gerasimenko, O. A. Grebenchikov, Yu. V. Skripkin, O. R. Onischenko, V. V. Likhvantsev, A. M. Ovezov

“…Patients were randomized (seed 6556 as of 04.01.2016, www.randomization.com) to Volatile Induction and Maintenance Anesthesia (VIMA) with Sevoflurane group (n = 65) and Total Intravenous Anesthesia with Propofol and Fentanyl (TIVA) group (n = 66). The changes in oxidative stress markers in blood plasma were studied: carbonylated proteins, nitrotyrosine, oxidized forms of low-density lipoproteins – oxy-LDL.Results. …”
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PHARMACOECONOMIC ANALYSIS OF THE IMPACT ON THE BUDGET COSTS OF ADDING DEXMEDETOMIDINE (DEXDOR) INTO THE LIST OF VITAL AND ESSENTIAL DRUGS by S. L. Plavinskiy, P. I. Shabalkin, A. E. Karelov

“…Analysis of  four pharmacoeconomic replacement models for  midazolam, propofol and  phentanyl with dexmedetomidine for sedation in resuscitation and intensive care unit (RICU) shows increase of the annual costs (at current prices) by 14-28 million rubles (at prices of the reference country – by 9-23 million rubles). …”
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Status epilepticus: Analysis of refractory cases by B. P. Gladov, O. A. Podgornaya, P. N. Vlasov

“…The investigators evaluated the efficiency of treatment regimens with intravenous antiepileptic drugs (AEDs), such as diazepam (DZP); valproic acid (VPA); levetiracetam; and lacosamide and their combinations, at the prehospital and hospital stages, as well as SE therapy complications noted only in the intravenous administration of narcotics (propofol, sodium thiopental).Results and discussion. …”
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Modern aspects in anesthesia of small laboratory animals by S. V. Gurova, M. V. Mindar, D. V. Khodakova

“…Since they are divided into groups depending on the routes of administration, we selected the following drugs from a number of articles: injectable anesthetics (medetomidine, dexmedetomidine, zoletil‑100, ketamine, xyla, propofol) and inhalation anesthetics (isoflurane, sevoflurane). …”
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Combined Extended High Spinal Anesthesia and Endotracheal Narcosis: a Clinical Case by A. B. Yakushevsky, A. N. Plekhanov, A. B. Ayusheev

“…After that endotracheal anesthesia was performed on the basis of fentanyl and propofol. This combination allowed to expand the scope of surgical intervention, provided adequate pain relief intraoperatively and in the postoperative period, without the use of narcotic analgesics. …”
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