Micro- and Nanostructured Devices for the Investigation of Biomolecular Interactions by Christophe Danelon, Martin G. Jenke, Christoph Schreiter, Gyu Man Kim, Jean-Baptiste Perez, Christian Santschi, Jürgen Brugger, Horst Vogel

“… Cell membrane receptors and ion channels are essential in many different cellular processes. …”
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Integrin alpha 6 homozygous splice-site mutation causes a new form of junctional epidermolysis bullosa in Charolais cattle by Mekki Boussaha, Arnaud Boulling, Valérie Wolgust, Lorraine Bourgeois-Brunel, Pauline Michot, Cécile Grohs, Nicolas Gaiani, Pierre-Yves Grivaud, Hélène Leclerc, Coralie Danchin-Burge, Marthe Vilotte, Julie Rivière, Didier Boichard, Jean-Marie Gourreau, Aurélien Capitan

“…The mutant mRNA is predicted to cause a frameshift (ITGA6 p.I657Mfs1) that affects the assembly of the integrin α6β4 dimer and its correct anchoring to the cell membrane. This dimer is a key component of the hemidesmosome anchoring complex, which ensures the attachment of basal epithelial cells to the basal membrane. …”
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The Role of Transporters in Future Chemotherapy by Johanna Huttunen, Kristiina M. Huttunen

“…Since these proteins, classified into solute carriers (SLCs) and ATP-binding cassettes (ABCs), can carry not only endogenous compounds, nutrients, and metabolites, but also drugs across the cell membranes, they have a crucial role in drug exposure and clinical outcomes of chemotherapeutics. …”
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