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The Anatomy of Knock
Published 2017“…For the “acoustic knock” mode, a knock intensity (KI) is defined as the pressure oscillation amplitude. …”
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Revisiting the “In-clustering” question in InGaN through the use of aberration-corrected electron microscopy below the knock-on threshold
Published 2013“…We employ atomically resolved CS-corrected scanning transmission electron microscopy and electron energy loss spectroscopy at 120 kV—which we demonstrate to be below the knock-on displacement threshold—and show that indium clustering is not present in as-grown In[subscript 0.22]Ga[subscript 0.78]N QWs. …”
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Profoundly different prion diseases in knock-in mice carrying single PrP codon substitutions associated with human diseases
Published 2014“…To explore the roots of this phenomenon, we created a knock-in mouse model carrying the mutation associated with one of these diseases [Creutzfeldt–Jakob disease (CJD)] that was exactly analogous to a previous knock-in model of a different prion disease [fatal familial insomnia (FFI)]. …”
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Layer-by-Layer Nanoparticles for Systemic Codelivery of an Anticancer Drug and siRNA for Potential Triple-Negative Breast Cancer Treatment
Published 2016“…A single nanoparticle platform has been developed through the modular and controlled layer-by-layer process to codeliver siRNA that knocks down a drug-resistance pathway in tumor cells and a chemotherapy drug to challenge a highly aggressive form of triple-negative breast cancer. …”
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Effects of ethanol content on gasohol PFI engine wide-open-throttle operation
Published 2011“…The NOx emission and knock characteristics of a PFI engine operating on ethanol/gasoline mixtures were assessed at 1500 and 2000 rpm with λ =1 under Wide-Open-Throttle condition. …”
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Dopaminergic Signaling in the Cochlea: Receptor Expression Patterns and Deletion Phenotypes
Published 2012“…The increased vulnerability in D2 knock-outs was seen in DPOAEs, suggesting a role for dopamine in the outer hair cell area. …”
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Characterization of FUS Mutations in Amyotrophic Lateral Sclerosis Using RNA-Seq
Published 2013“…Pathway analysis revealed that overexpression of wild-type FUS regulates ribosomal genes, whereas knock-down of FUS additionally affects expression of spliceosome related genes. …”
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Ignition Delay Correlation for Engine Operating with Lean and with Rich Fuel-Air Mixtures
Published 2017“…An algorithm has been devised to identify the knock point on individual pressure traces so that the large data set (of some thirty three thousand cycles) could be processed automatically. …”
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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense
Published 2014“…Consistent with the human polymorphism, T300A knock-in mice do not develop spontaneous intestinal inflammation, but exhibit morphological defects in Paneth and goblet cells. …”
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Inferring regulatory networks from multiple sources of genomic data
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Aberrant Development and Plasticity of Excitatory Visual Cortical Networks in the Absence of cpg15
Published 2014“…Here we show that global knock-out of cpg15 results in abnormal postnatal development of the excitatory network in visual cortex and an associated disruption in development of visual receptive field properties. …”
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Global microRNA depletion suppresses tumor angiogenesis
Published 2014“…We generated microRNA-deficient tumors by knocking out Dicer1. These tumors are highly hypoxic but poorly vascularized, suggestive of deficient angiogenesis signaling. …”
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Image informatics for studying signal transduction in cells interacting with 3D matrices
Published 2015“…Preliminary results suggest that knocking down all rSMAD components affects fibroblast response to TGFβ1 and TGFβ3 isoforms in different ways, and suggest a potential role for SMAD1 and SMAD5 in regulating TGFβ isoform response. …”
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Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress
Published 2017“…Associated with this enhanced resilience of female mice upon NAc knock-out of Dnmt3a was a partial shift of the NAc female transcriptome toward the male pattern after SCVS. …”
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