Phenotypic Evolution of Therapeutic Salmonella enterica Serovar Typhimurium after Invasion of TRAMP Mouse Prostate Tumor by Choe, Elizabeth, Kazmierczak, Robert A., Eisenstark, Abraham

“…Thus, we have made an initial examination of selected phenotypes in a therapeutic Salmonella enterica serovar Typhimurium population developed from an archival wild-type LT2 strain and intraperitoneally injected into a 6-month-old TRAMP (transgenic adenocarcinoma of mouse prostate) mouse. …”
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Activation of tolerogenic dendritic cells in the tumor draining lymph CD8+ T cells engineered to express CD40 ligand by Higham, Eileen M., Wittrup, Karl Dane, Chen, Jianzhu

“…The antitumor CD8[supersript +] T cell response was further enhanced if TRAMP mice were also immunized with a tumor-specific Ag. …”
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Persistence of tumor-infiltrating CD8 T cells is tumor-dependent but antigen-independent by Olurinde, Mobolaji O., Drake, Adam, Bai, Ailin, Chen, Jianzhu, Shen, Chase

“…We have previously developed a modified TRansgenic Adenocarcinoma of the Mouse Prostate (TRAMP) model where prostate cancer cells express the T-cell epitope SIYRYYGL (SIY) recognized by CD8 T cells expressing the 2C T-cell receptor (TCR) (referred to as TRP-SIY mice). …”
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GPR56 Plays Varying Roles in Endogenous Cancer Progression by Xu, Lei, Begum, Shahinoor, Barry, Marc, Crowley, Denise G., Yang, Liquan, Bronson, Roderick T., Hynes, Richard O.

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