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Noninvasive electron microscopy with interaction-free quantum measurements
Published 2010“…We propose the use of interaction-free quantum measurements with electrons to eliminate sample damage in electron microscopy. This might allow noninvasive molecular-resolution imaging. …”
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Directed evolution of APEX2 for electron microscopy and proximity labeling
Published 2017“…APEX is an engineered peroxidase that functions as an electron microscopy tag and a promiscuous labeling enzyme for live-cell proteomics. …”
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Grids for Applications in High-Temperature High-Resolution Transmission Electron Microscopy
Published 2011“…Such coated TEM grids are very much desired for applications in high-temperature high-resolution transmission electron microscopy.…”
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Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy
Published 2015“…Electron microscopy (EM) is the standard method for imaging cellular structures with nanometer resolution, but existing genetic tags are inactive in most cellular compartments[superscript 1] or require light and can be difficult to use[superscript 2]. …”
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Modular architecture of eukaryotic RNase P and RNase MRP revealed by electron microscopy
Published 2012“…The structures of RNase P and RNase MRP have not yet been solved, so it is unclear how the proteins contribute to the structure of the complexes and how substrate specificity is determined. Using electron microscopy and image processing we show that eukaryotic RNase P and RNase MRP have a modular architecture, where proteins stabilize the RNA fold and contribute to cavities, channels and chambers between the modules. …”
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Reactive ion etching: Optimized diamond membrane fabrication for transmission electron microscopy
Published 2014“…The samples are examined by Raman spectroscopy and high-resolution transmission electron microscopy (TEM). Raman spectra indicate that the crystalline structure of the RIE-processed diamond is preserved, while the FIB-processed diamond membrane has a broad-background sp[superscript 2] feature. …”
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Transmission electron microscopy study of Pb-depleted disks in PbTe-based alloys
Published 2013“…Because of the effects of diffraction contrast imaging by transmission electron microscopy and orientations of the crystals, these native lattice strain fields were incorrectly recognized as precipitates or nanoinclusions in PbTe-based materials. …”
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Zernike Phase Contrast Cryo-Electron Microscopy and Tomography for Structure Determination at Nanometer and Subnanometer Resolutions
Published 2015“…Zernike phase contrast cryo-electron microscopy (ZPC-cryoEM) is an emerging technique that is capable of producing higher image contrast than conventional cryoEM. …”
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Revisiting the “In-clustering” question in InGaN through the use of aberration-corrected electron microscopy below the knock-on threshold
Published 2013“…We employ atomically resolved CS-corrected scanning transmission electron microscopy and electron energy loss spectroscopy at 120 kV—which we demonstrate to be below the knock-on displacement threshold—and show that indium clustering is not present in as-grown In[subscript 0.22]Ga[subscript 0.78]N QWs. …”
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Hierarchical structural design for fracture resistance in the shell of the pteropod Clio pyramidata
Published 2017“…Microindentation and electron microscopy studies reveal that the helical organization of the fibrous building blocks effectively constrains mechanical damages through tortuous crack propagation. …”
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Plasticity of Intermediate Filament Subunits
Published 2010“…So far, IF subunits have mainly been observed by electron microscopy of glycerol sprayed and rotary metal shadowed specimens. …”
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Sub-10-nm half-pitch electron-beam lithography by using poly(methyl methacrylate) as a negative resist
Published 2012“…In addition to scanning electron microscopy metrology, transmission electron microscopy metrology was done to confirm the high-resolution capability of negative-tone PMMA. …”
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The origins of pressure-induced phase transformations during the surface texturing of silicon using femtosecond laser irradiation
Published 2013“…In this work, we investigate the light-material interaction during the texturing of silicon by directly correlating the formation of pressure-induced silicon polymorphs, fs-laser irradiation conditions, and the resulting morphology and microstructure using scanning electron microscopy, micro-Raman spectroscopy, and transmission electron microscopy. …”
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Twinning-like lattice reorientation without a crystallographic twinning plane
Published 2015“…Aberration-corrected transmission electron microscopy observations reveal that the boundary between the parent lattice and the ‘twin’ lattice is composed predominantly of semicoherent basal/prismatic interfaces instead of the {10[bar over 1]2} twinning plane. …”
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Single Stranded DNA Induced Assembly of Gold Nanoparticles
Published 2003“…From these experimental findings, a single stranded DNA (ssDNA) based method to assimilate 13 and 5 nm gold nanoparticles was developed, and verified by transmission electron microscopy (TEM).…”
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Conformational dynamics of supramolecular protein assemblies
Published 2017“…Results are publically available for use in further investigation and interpretation of biological function including cooperative transitions, allosteric communication, and molecular mechanics, as well as in further classification and refinement of electron microscopy based structures.…”
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Pressure-induced phase transformations during femtosecond-laser doping of silicon
Published 2013“…Specifically, the transformation from diamond cubic Si-I to pressure-induced polymorphic crystal structures (amorphous Si, Si-XII, and Si-III) during femtosecond-laser irradiation was investigated using scanning electron microscopy, Raman spectroscopy, and transmission electron microscopy. …”
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Platinum-Alloy Cathode Catalyst Degradation in Proton Exchange Membrane Fuel Cells: Nanometer-Scale Compositional and Morphological Changes
Published 2013“…Electrochemical measurements showed an ≈75% Pt surface area loss and an ≈40% specific activity loss for a membrane electrode assembly (MEA) cathode with acid-treated “Pt[subscript 3]Co ” catalyst particles in a H[subscript 2]/N[subscript 2] proton exchange membrane fuel cell after 24h voltage cycling between 0.65 and 1.05V vs reversible hydrogen electrode. Transmission electron microscopy, scanning transmission electron microscopy, associated X-ray energy dispersive spectroscopy, and high angle annular dark-field techniques were used to probe the microstructural changes of the MEA cathode and the compositional changes along the MEA cathode thickness and within individual Pt[subscript x]Co nanoparticles before and after voltage cycling. …”
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Complexin Mutants Reveal Partial Segregation between Recycling Pathways That Drive Evoked and Spontaneous Neurotransmission
Published 2017“…We combined loading of the lipophilic dye FM1–43 with photoconversion, electron microscopy, and electrophysiology to monitor evoked and spontaneous recycling vesicle pools. …”
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