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Light microscopy mapping of connections in the intact brain
Published 2016“…Here we review recent light-microscopy-based approaches that may help in integration across scales.…”
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Quantitative polarized light microscopy of human cochlear sections
Published 2015“…We provide the first characterization of the polarization dependent optical properties of human cochlear sections using quantitative polarized light microscopy (qPLM). Eight pediatric cadaveric cochlear sections, aged 0 (term) to 24 months, were selected from the US National Temporal Bone Registry, imaged with qPLM and analyzed using Image J. …”
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Quantitative polarized light microscopy of unstained mammalian cochlear sections
Published 2013“…Here, we focus on that characterization using quantitative polarized light microscopy (qPLM) applied to unstained cochlear sections of the mouse, a common animal model of human hearing loss. …”
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Laser Microdissection of the Alveolar Duct Enables Single-Cell Genomic Analysis
Published 2017“…The lung slices were examined by transmission light microscopy to target the alveolar duct. The air-filled lung was sufficiently accessible by light microscopy that counterstains or fluorescent labels were unnecessary to identify the alveolar duct. …”
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Label-free volumetric optical imaging of intact murine brains
Published 2017“…Different approaches have been utilized to decipher neuronal circuits, including electron microscopy (EM) and light microscopy (LM). However, these approaches typically demand extensive sectioning and reconstruction for a brain sample. …”
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Virtual Hematoxylin and Eosin Transillumination Microscopy Using Epi-Fluorescence Imaging
Published 2017“…We derive a physically realistic model for the generation of virtual transillumination, white light microscopy images using epi-fluorescence measurements from thick, unsectioned tissue. …”
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Effects of Monofunctional Platinum Agents on Bacterial Growth: A Retrospective Study
Published 2015“…E. coli filamentation was observed by light microscopy when cells were grown in the presence of phenanthriplatin, cis-[Pt(NH[subscript 3])[subscript 2](Am)Cl][superscript +] where Am is phenanthridine. …”
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The Impact of Weld Metal Creep Strength on the Overall Creep Strength of 9% Cr Steel Weldments
Published 2013“…For investigations of the failure modes, cross sections of fractured samples were investigated by optical light microscopy, scanning electron microscopy, and electron backscatter diffraction. …”
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Analysis and prediction of defects in UV photo-initiated polymer microarrays
Published 2014“…In this study a library of materials expressed on the microarray format are assessed by light microscopy, atomic force microscopy and time-of-flight secondary ion mass spectrometry to identify compositions with defects that cause a polymer spot to exhibit surface properties significantly different from a smooth, round, chemically homogeneous ‘normal’ spot. …”
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Enumeration of islets by nuclei counting and light microscopic analysis
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Moderate dynamic compression inhibits pro-catabolic response of cartilage to mechanical injury, TNF-α and IL-6, but accentuates degradation above a strain threshold
Published 2015“…Outcome measures included sulfated glycosaminoglycan (sGAG) loss (dimethylmethylene blue (DMMB)), aggrecan biosynthesis ([superscript 35]S-incorporation), aggrecanase activity (Western blot), chondrocyte viability (fluorescence staining) and apoptosis (nuclear blebbing via light microscopy), and gene expression (qPCR). Results In bovine explants, cytokine alone and injury-plus-cytokine treatments markedly increased sGAG loss and aggrecanase activity, and induced chondrocyte apoptosis. …”
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