The Correlation between the Cardiac and Hepatic Iron-Overload in Patients with Thalassemia Major Who Received Multiple Transfusion by Hamid Kalantari, Neda Rad, Taleb Azarm

“…Pearson’s tests gave a significant correlation coefficient between cardiac iron-overloaded and hepatic iron-overloaded (r = 0.29, P < 0.001). …”
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Correlation of serum ferritin levels, echocardiography parameters, and cardiac magnetic resonance imaging with T2 weighting in patients with beta-thalassemia major by Ali Mohammadzadeh, Mobin Mohebi, Maryam Mohammadadeh, Madjid Shakiba, Layla Shojaie

“…Background and Aim: Beta thalassemia often leads to iron overload in various tissues, including the heart. …”
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Comparing Pituitary MRI Findings in Patients with Thalassemia with and without Delayed Puberty by Atoosa Adibi, Ali Hekmatnia, Maryam Moradi, Ali Asghar Rahmani, Mohammad Hassan Moaddab

“…Blood transfusion, as the main stem of management of these patients, has numerous side effects including iron overload. Delayed puberty as a major complication of these patients is multifactorial but seems to be mainly secondary to iron deposition within pituitary gland. …”
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Gene therapy in beta thalassemia: a review article by Hadis Soleimanzadeh, Nahid Nasiri

“…Current treatments such as transfusion, iron chelating agents and allogeneic stem cell hematopoietic transplantation have limitations in their use, including iron overload, lack of a human leukocyte antigen (HLA) matched compatible donor, and graft versus host disease (GVHD). …”
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