Ropivacaine inhibits proliferation, migration and invasion of human liver cancer cell line Hep3B by SUN Quan-peng, FAN Chao, ZHAN De-xi, FAN Yi-ming, SUN Wei-feng

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Downregulation of demethylase FTO inhibits proliferation of human liver cancer cell line HepG2 by LU Huiying, WANG Jianguo

“…Objective To explore the mechanism of the demethylase fat mass and obesity associatal(FTO) gene on the proliferation of human liver cancer cell line HepG2. Methods HepG2 cells were divided into the control group, FTO group (transfected with FTO over-expression plasmid), si-FTO group (transfected with si-FTO)and si-FTO+si-FoxO1 group (simultaneously transfected with si-FTO and si-FoxO1). …”
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Down-regulation of Notch1 gene promotes autophagy of human liver cancer cell line HepG2 by LI Chang-an, LIU Chun-xiu, XIE Xiao-juan, SUN Ai-ping

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Construction of humanized chimeric mice with Tet-on regulating liver specific expression of uPA using CRISPR/Cas9 technology by BAI Jiasi, MAO Qing

“…Objective To construct NOD-SCID transgenic mice with Tet-on regulated liver specific expression of urokinase plasmin activator (uPA), repair subacute liver injury in mice through human liver cancer cell transplantation, and thereby establish humanized liver cell chimeric mice. …”
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Identification of the effect of cisplatin on the transcriptome of human hepatocellular carcinoma cell lines by GUO Xin, JI Mengdie, WANG Qi, LI Xueyuan, CHEN Yang

“…Objective To investigate the effect of cisplatin treatment on the transcriptional level of human liver cancer cells by conducting transcriptome sequencing analysis after treating human liver cancer cell lines with different concentrations of cisplatin (CDDP). …”
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Study on the significance and mechanism of ASGR1 in hepatocellular carcinoma by LI Qianyu, GUO Wenyun, QIAN Yifei, LI Songling, ZHU Zijun, LIU Yanfeng

“…The Human Protein Atlas (HPA) database was used to obtain the immunohistochemistry (IHC) data of normal human liver tissue and liver cancer tissue to analyze the protein expression of ASGR1. …”
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Aucubin inhibits the proliferation of human hepatocellular carcinoma cells line HepG2 by AN Qi, QI Guangzhao, HAN Chao

“…Objective To investigate the effects of aucubin (AU) on the proliferation, apoptosis, and cell cycle of human liver cancer cells line HepG2 and its mechanism of action. …”
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Culture systems for transformations of hydatid cysts from protoscoleces in vitro by WU Hongye, LI Kai, WANG Fen, LIU Xunuo, FAN Junjie, YE Bin

“…Methods Based on the basic cell culture media RPMI1640 or DMEM, and fetal calf serum or sheep serum as nutrients, and human liver cell line L02 as server cells, culture systems for transformations of protoscoleces into hydatid cysts in vitro were established based on block designs. …”
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Resveratrol promotes hepatic lipid decomposition by regulating ATGL/CGI58 and Rab7/LC3β through perilipin 2 by YANG Yilin, ZHANG Yan, QIN Yu, MI Mantian

“…Objective To investigate the effect of resveratrol (RSV) on enhancing hepatic lipolysis and lipophagy through perilipin 2 (PLIN2), and elucidate its underlying mechanism. Methods Human liver cell line HHL-5 was used to establish a cellular model of steatosis, and then the cells were divided into control group, palmitic acid (PA, model) group, siPLIN2 transfection group and RSV treatment groups (5, 10, 20, 40 μmol/L). …”
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