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Exploratory study of serum IL-36 subfamily as biomarkers of disease progression in lupus nephritis
Published 2023-10-01“…Objective To explore whether or not serum interleukin (IL)-36 subfamily may serve as biomarkers for disease progression in lupus nephritis (LN). …”
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ANALYSIS OF THE FAMILY OF A PATIENT WITH X-LINKED ADRENOLEUKODYSTROPHY AND LITERATURE REVIEW
Published 2023-10-01Subjects: “…adrenoleukodystrophy|atp binding cassette transporter, subfamily d, member 1|mutation…”
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Role of interleukin-36 in kidney disease
Published 2023-11-01“…And co-receptor of IL-36 subfamily is IL-36 receptor (IL-36R). An imbalance of IL-36 agonists and antagonists may lead to the development of skin diseases, intestinal diseases, lung diseases and tumors. …”
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Progress in the role of NR4A1 in the development of diabetic nephropathy
Published 2023-10-01“…As a member of the nuclear receptor subfamily, NR4A1 works with glycerol kinase, a key glucose and lipid metabolism enzyme, to lower blood glucose and boost blood lipids and maintain glucose and lipid homeostasis, while NR4A1 deficiency leads to disruption of hepatic glucose and lipid metabolism. …”
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Exploring the Role of PCDHGB4 in the Occurrence of Lung Squamous Cell Carcinoma Based on Bioinformatics Analysis
Published 2024-03-01“…Protocadherin-gamma subfamily B4 (PCDHGB4) as a family member in LUSC was rarely reported. …”
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Lipid Goal Attainment Rate and Influencing Factors in 45-year-old or Younger Acute Coronary Syndrome Patients with an Ultra-high Risk of Atherosclerotic Cardiovascular Disease afte...
Published 2023-09-01“…Attainment and non-attainment groups had statistically significant differences in the ratio of having a diabetes history, prevalence of previous acute myocardial infarction (AMI) , results of adenosine triphosphate-binding cassette subfamily B member 1 (ABCB1) and solute carrier organic anion transporter family member 1B1 (SLCO1B1) , levels of TC and TG, and baseline levels of LDL-C and non-HDL-C, as well as lipid-lowering therapies (P<0.05) . …”
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miR-185-5p facilitates intracellular Mycobacterium growth via inhibiting macrophage autophagy
Published 2023-06-01“…Through target genes prediction and GO and KEGG functional enrichment analysis, it was found that miR-185-5p might play a role in autophagy regulation by targeting nuclear receptor subfamily 1 group D member 1 (NR1D1), Ras-related protein Rab-35 (RAB35), cell division control protein 42 homolog (CDC42), etc.Conclusion·Mycobacterium infection can induce the up-regulation of miR-185-5p in both macrophages and exosomes, and miR-185-5p can inhibit the autophagy process of macrophages by inhibiting the formation of autophagosomes, which can promote the growth and survival of intracellular Mycobacterium.…”
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