An inter-species protein-protein interaction network across vast evolutionary distance -н Zhong, Quan, Pevzner, Samuel J., Hao, Tong, Wang, Yang, Mosca, Roberto, Menche, Jörg, Taipale, Mikko, Taşan, Murat, Fan, Changyu, Yang, Xinping, Haley, Patrick, Murray, Ryan R., Mer, Flora, Gebreab, Fana, Tam, Stanley, MacWilliams, Andrew, Dricot, Amélie, Reichert, Patrick, Santhanam, Balaji, Ghamsari, Lila, Calderwood, Michael A., Rolland, Thomas, Charloteaux, Benoit, Lindquist, Susan, Barabási, Albert‐László, Hill, David E., Aloy, Patrick, Cusick, Michael E., Xia, Yu, Roth, Frederick P., Vidal, Marc

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Chemogenomics and orthology‐based design of antibiotic combination therapies -н Chandrasekaran, Sriram, Cokol‐Cakmak, Melike, Sahin, Nil, Yilancioglu, Kaan, Kazan, Hilal, Collins, James J., Cokol, Murat

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Reply to "Do genome-scale models need exact solvers or clearer standards?" -н Chindelevitch, Leonid, Regev, Aviv, Berger Leighton, Bonnie, Trigg, Jason

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TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse -н Yang, Fang, Silber, Sherman, Leu, N. Adrian, Oates, Robert D., Marszalek, Janet D., Skaletsky, Helen, Brown, Laura G., Rozen, Steve, Wang, P. Jeremy, Page, David C

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Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis -н Wang, Eric T, Housman, David E

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Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models -н Kaeppler, JR, Chen, J, Buono, M, Vermeer, J, Kannan, P, Cheng, W, Voukantsis, D, Thompson, JM, Hill, MA, Allen, D, Gomes, A, Kersemans, V, Kinchesh, P, Smart, S, Buffa, F, Nerlov, C, Muschel, RJ, Markelc, B

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Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium. -н van Noort, V, Seebacher, J, Bader, S, Mohammed, S, Vonkova, I, Betts, M, Kühner, S, Kumar, R, Maier, T, O'Flaherty, M, Rybin, V, Schmeisky, A, Yus, E, Stülke, J, Serrano, L, Russell, R, Heck, A, Bork, P, Gavin, A

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YY1 binding is a gene-intrinsic barrier to Xist-mediated gene silencing -н Bowness, JS, Almeida, M, Nesterova, T, Brockdorff, N

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NAADP-regulated two-pore channels drive phagocytosis through endo-lysosomal Ca2+ nanodomains, calcineurin and dynamin -н Davis, LC, Morgan, AJ, Galione, A

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HES6 drives a critical AR transcriptional programme to induce castration‐resistant prostate cancer through activation of an E2F1‐mediated cell cycle network -н Ramos-Montoya, A, Lamb, A, Russell, R, Carroll, T, Jurmeister, S, Galeano-Dalmau, N, Massie, C, Boren, J, Bon, H, Theodorou, V, Vias, M, Shaw, G, Sharma, N, Ross-Adams, H, Scott, H, Vowler, S, Howat, W, Warren, A, Wooster, R, Mills, I, Neal, D

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EMC is required for biogenesis of Xport-A, an essential chaperone of Rhodopsin-1 and the TRP channel -н Gaspar, CJ, Vieira, LC, Santos, CC, Christianson, JC, Jakubec, D, Strisovsky, K, Adrain, C, Domingos, PM

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Antisense transcription-dependent chromatin signature modulates sense transcript dynamics -н Brown, T, Howe, F, Murray, S, Wouters, M, Lorenz, P, Seward, E, Rata, S, Angel, A, Mellor, E

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MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B -н Pefani, D, Tognoli, M, Pirincci Ercan, D, Gorgoulis, V, O'Neill, E

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Phospho‐regulation, nucleotide binding and ion access control in potassium‐chloride cotransporters -н Chi, G, Ebenhoch, R, Man, H, Tang, H, Tremblay, LE, Reggiano, G, Qiu, X, Bohstedt, T, Liko, I, Almeida, FG, Garneau, AP, Wang, D, McKinley, G, Moreau, CP, Bountra, KD, Abrusci, P, Mukhopadhyay, SMM, Fernandez‐Cid, A, Slimani, S, Lavoie, JL, Burgess‐Brown, NA, Tehan, B, DiMaio, F, Jazayeri, A, Robinson, CV, Dürr, KL

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TECPR1 conjugates LC3 to damaged endomembranes upon detection of sphingomyelin exposure -н Boyle, KB, Ellison, CJ, Elliott, PR, Schuschnig, M, Grimes, K, Dionne, MS, Sasakawa, C, Munro, S, Martens, S, Randow, F

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Small-molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling -н Gyrd-Hansen, M, Hdrinka, M, Schlicher, L, Dai, B, Pinkas, DM, Bufton, JC, Picaud, S, Ward, JA, Rogers, C, Huber, KVM, Filippakopoulos, P, Bullock, AN, Degterev, A

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ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules -н Gai, M, Bianchi, F, Vagnoni, C, Vernì, F, Bonaccorsi, S, Pasquero, S, Berto, G, Sgrò, F, Chiotto, A, Annaratone, L, Sapino, A, Bergo, A, Landsberger, N, Bond, J, Huttner, W, Di Cunto, F

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Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis -н Maelfait, J, Liverpool, L, Bridgeman, A, Ragan, K, Upton, J, Rehwinkel, J

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The p97-Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8 -н Singh, A, Oehler, J, Torrecilla, I, Kilgas, S, Li, S, Vaz, B, Guérillon, C, Fielden, J, Hernandez-Carralero, E, Cabrera, E, Tullis, I, Meerang, M, Barber, P, Freire, R, Parsons, J, Vojnovic, B, Kiltie, A, Mailand, N, Ramadan, K

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Capture-C reveals preformed chromatin interactions between HIF-binding sites and distant promoters -н Platt, J, Salama, R, Smythies, J, Choudhry, H, Davies, J, Hughes, J, Ratcliffe, P, Mole, D

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