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41
Nanopore sequencing analysis of integron gene cassettes in sewages and soils
Published 2023Subjects: Get full text
Journal Article -
42
Application of feature selection algorithms in gene expression data analysis
Published 2010“…Although there are several causes of cancer, scientists have made a major breakthrough in discovering a number of candidate genes that associated with certain cancers. These genes, recognized as biomarkers, can contribute in early cancer diagnosis and prognosis and hence raise the possibility of curative surgery. …”
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Final Year Project (FYP) -
43
Gene expression regulation by well-known non-coding RNAs
Published 2015“…From there, we could screen for genes important for XCI by rescuing the differentiated transgenic ES cells by gene silencing. …”
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Thesis -
44
Governance of heritable human gene editing world-wide and beyond
Published 2022Get full text
Article -
45
Identification of FGF receptor-binding peptides for cancer gene therapy
Published 2002“…These peptides should provide useful ligands for specific delivery of gene therapy vectors to clinically relevant targets.…”
Journal article -
46
Genotype-phenotype maps for gene networks: from evolution to computation
Published 2017“…</p> <p>Next, we investigate multiple models of GP maps for gene regulatory networks (GRNs). These include Boolean threshold networks, where we fix the strength of gene interactions, while varying the network topology, as well as systems of differential equations, where we fix the network topology while varying interaction strengths. …”
Thesis -
47
Association between cognition and gene polymorphisms involved in thrombosis and haemostasis
Published 2015Journal article -
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49
In vitro reconstitution of liquid-liquid phase separation in regulating gene transcription
Published 2020“…Liquid-liquid phase separation (LLPS) has become a popular topic of study as more evidence of this process being involved in major processes, such as gene transcription of living cells, are being discovered. …”
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Final Year Project (FYP) -
50
Graph embeddings on gene ontology annotations for protein-protein interaction prediction
Published 2021“…Protein-protein interaction (PPI) prediction is an important task towards the understanding of many bioinformatics functions and applications, such as predicting protein functions, gene-disease associations and disease-drug associations. …”
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Journal Article -
51
Epigenetic regulation of gene expression in human malaria parasite Plasmodium falciparum.
Published 2011“…We also observed the enrichment of these modifications on certain genes across the intraerythrocytic developmental cycle (IDC) of the parasite. …”
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Final Year Project (FYP) -
52
Blue light system for transcriptional activation and repression of gene expression in bacteria
Published 2016“…The objective of this project is to make a blue light system, which facilitates the experiment on light-mediated transcriptional activation and repression of gene expression in bacteria. Along the way, the design of circuit, control program and 3D model are carried out, after which the physical blue light system is also built,improved and tested to be used in experiments.…”
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Thesis -
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54
Spatial and subcellular gene expression patterns in myogenic differentiation and muscle pathology
Published 2024“…Promising dystrophin-restoration therapies such as gene editing using the CRISPR-Cas9 system and antisense oligonucleotide-mediated exon skipping using peptide-phosphorodiamidate morpholino oligomers (PPMOs) are currently in development. …”
Thesis -
55
Virulence gene profiles and antimicrobial susceptibility of Salmonella Brancaster from chicken
Published 2023“…Two sets of multiplex polymerase chain reaction (PCR) were conducted to identify eight virulence genes associated with pathogenicity in Salmonella (invasion protein gene [invA], Salmonella invasion protein gene [sipB], Salmonella-induced filament gene [sifA], cytolethal-distending toxin B gene [cdtB], Salmonella iron transporter gene [sitC], Salmonella pathogenicity islands gene [spiA], Salmonella plasmid virulence gene [spvB], and inositol phosphate phosphatase gene [sopB]). …”
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Article -
56
Phenol degradation and molecular validation of phenol hydroxylase gene of Alcaligenes faecalis
Published 2015“…The gene was amplified by using PCR technique with an annealing temperature of 56.4°C. …”
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Project Paper Report -
57
Runx family genes in a cartilaginous Fish, the elephant Shark (Callorhinchus milii)
Published 2014“…The expression profiles of elephant shark Runx genes are similar to those of mammalian Runx genes. …”
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Journal Article -
58
Do the genes justify the ends? Ethical and legal aspects of human genetic technology.
Published 2008“…A discussion of the legal and ethical aspects of Human Genetic Technology, specifically in the areas of Genetic Screening, Gene Therapy, Human Genetic Research and Patenting of genes. …”
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Final Year Project (FYP) -
59
Identification of a Gene Signature That Predicts Dependence upon YAP/TAZ-TEAD
Published 2024“…Here, we used a combination of RNA-seq and bioinformatic analysis of metastatic melanoma cells to develop a YAP/TAZ gene signature. We found that the genes in this signature are TEAD-dependent in several melanoma cell lines, and that their expression strongly correlates with YAP/TAZ activation in human melanomas. …”
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Article -
60
Generation of Rhesus Macaque Embryos with Expanded CAG Trinucleotide Repeats in the Huntingtin Gene
Published 2024“…Huntington’s disease (HD) arises from expanded CAG repeats in exon 1 of the <i>Huntingtin</i> (<i>HTT</i>) gene. The resultant misfolded HTT protein accumulates within neuronal cells, negatively impacting their function and survival. …”
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Article