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21
Minimally invasive inspection of technical and medical intracavities using a novel opto-digital scheme
Published 2010“…Cancer growths found in body cavities, such as colon, are a leading cause of death all over world. …”
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Research Report -
22
Ingestible artificial urinary biomarker probes for urine test of gastrointestinal cancer
Published 2024“…Such signal readout is correlated with the urinary tetrazine concentration and thus measures the level of cancer biomarkers in the colon. HATS-based optical urinalysis detects orthotopic colon tumors two weeks earlier than clinical serological tests and can be developed to a point-of-care paper test. …”
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Journal Article -
23
Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation
Published 2013“…We show here that colon cancer cell lines express also the paralog APC-like (APCL or APC2). …”
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Journal Article -
24
Ontogeny of intestinal intratumoural macrophages and their contribution in cancer regulation
Published 2018“…Interestingly, in colon adenomas F4/80(hi)MHCII(lo) cells become the dominant macrophage fraction during tumour progression. …”
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Thesis -
25
Diet-wide analyses for risk of colorectal cancer: prospective study of 12,251 incident cases among 542,778 women in the UK
Published 2025“…Genetically predicted milk consumption was inversely associated with risk of colorectal, colon, and rectal cancers. We conclude that dairy products help protect against colorectal cancer, and that this is driven largely or wholly by calcium.…”
Journal article -
26
Modulatory effects of isolated Lactobacillus paracasei from Malaysian water kefir grains on the intestinal barrier and gut microbiota in diabetic mice
Published 2024“…The present study aimed to evaluate the regulatory effects of Lactobacillus paracasei isolated from Malaysian water kefir grains (MWKG) on the alterations of intestinal barrier and gut microbiota in diabetic mice via histopathological analysis of the distal colon and 16S rRNA gene sequencing on fecal microbiome. …”
Article -
27
The development of automatic flexible endoscopes for gastrointestinal inspection or surgery
Published 2008“…Colonoscopy is commonly used in the diagnosis of colonic pathology like cancer of the colon. At present, the colonoscopic procedure is often unpleasant for the patient and technically demanding for the endoscopist. …”
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Thesis -
28
Computerized detection of lumen boundary in robotic colonoscopy for medical diagnosis
Published 2009“…A Colonoscope is an endoscopic instrument used by physicians to view the inside of the colon for diagnosing possible colonic diseases. In difficult cases of diagnostic colonoscopy, the tip of the endoscope may not be properly maneuverable and controllable. …”
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Thesis -
29
Studying the dose-dependent effect of honey on the modulation of the infant microbiome
Published 2018“…Prebiotics can stimulate the growth or activity of beneficial bacteria in the colon. Some Australian honeys have been shown to have prebiotic properties in adults and children with doses of 1% in microcosm experiments, but dose response studies are lacking. …”
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Thesis -
30
A 3D printable tissue adhesive
Published 2024“…In vivo rat trachea and colon defect models demonstrate the fluid-tight tissue sealing capability of the printed patches, which maintained adhesion over 4 weeks. …”
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Article -
31
Understanding tumor cell plasticity in spatial transcriptomics with graph attention networks and walk-based pseudotime analysis
Published 2024“…The utility of our approach is validated in model systems, specifically in the brain and colon, where it successfully identifies biologically relevant neighborhoods and maps differentiation pathways. …”
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Thesis -
32
Toxicological evaluation of Sargassum polycystum in mice with loperamide-induced constipation
Published 2024“…Histopathological examinations revealed non-toxic effects in liver, kidney and colon tissue samples from the SPE-treated groups compared with the control and constipation groups. …”
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Article -
33
Determination of the life span of inflammatory dendritic cells
Published 2014“…Furthermore, we revealed the localization of Plet-1+ DC in PP and colon using immunohistological staining consistent to the result in the previous studies. …”
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Final Year Project (FYP) -
34
Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis
Published 2024“…Here, we use single-cell RNA sequencing of colon lamina propria leukocytes (LPLs) along with RNA-seq and ATAC-seq of purified CD4<sup>+</sup> T cells to show that the transcription factors Blimp-1 (encoded by Prdm1) and c-Maf co-dominantly regulate Il10 while negatively regulating proinflammatory cytokines in effector T cells. …”
Journal article -
35
Taurine prevents mitochondrial dysfunction and protects mitochondria from reactive oxygen species and deuterium toxicity
Published 2025“…We describe how taurine could potentially alleviate deuterium stress, primarily through metabolic collaboration among various gut microflora to produce deuterium depleted nutrients and deuterium depleted water, and in this way protect against leaky gut barrier, inflammatory bowel disease, and colon cancer.…”
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Article -
36
Elucidating the non-apoptotic role of the caspases in the Drosophila intestinal system
Published 2019“…Furthermore, these findings could explain the correlation between caspase-9 misexpression and the bad prognosis observed in patients suffering from colon cancer. </p>…”
Thesis -
37
Prospective study of UV exposure and cancer incidence among Swedish women
Published 2011“…</p> <p><b>Results:</b> 2,303 incident cases of cancer were diagnosed (breast: 1,053, ovary: 126, lung: 116, colon-rectum: 133, and brain: 116). No associations were found between any cumulative measure of UV exposure at ages 10 to 39 years and overall cancer risk. …”
Journal article -
38
Estimating parameter distributions and developing epidemiological methods and tools to support gastrointestinal outbreak investigation
Published 2018“…The mathematical model estimated an incubation period of 9.6 days for <em>Salmonella</em> Typhi, and parameters strongly correlated with incubation period included the net population of bacteria in the colon and bacterial growth during systemic infection.…”
Thesis -
39
In vitro and In vivo photothermal cancer therapeutic effects of gold nanorods modified with mushroom β-glucan
Published 2020“…AuNR-Glu nanohybrids had a high photothermal transduction efficiency (η) of 43.12%, causing effective in vitro cell ablation in both HT-29 (94.2 ± 0.8% cell death) and SW480 (94.8 ± 1.1% cell death) colon cancer cells under 1064 nm NIR-II laser irradiation at 1.0 W/cm2. …”
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Journal Article -
40
Developing a personalized heterologous prime boost vaccination strategy for tumor therapy
Published 2021“…Mice primed with SNP encoding the neoantigen Reps1 for a colon carcinoma (MC38) and boosted with ChAdOx1 IV encoding Reps1 elicited on average ~40% Reps1-specific CD8 T cell responses, which were ~4x higher than mice boosted by the conventional IM route. …”
Thesis