Characterization of the alternative splicing regulating the proapoptotic gene BIM. by Lee, Qing Feng.

“…BCL2-homology domain 3 (BH3), essential for proapoptotic function of BIM, is included or excluded from the final BIM protein by means of alternative splicing and it is encoded in Exon 4. Therefore we hypothesized that BIM Exon 4 contains cis-acting elements - Exonic Splicing Enhancers (ESEs) or Exonic Splicing Silencers (ESSs) - , which activate or repress splicing of BIM Exon 4 respectively. …”
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Identification of alternative-splicing events in human monocyte differentiation by Sim, Donald Yuhui

“…The alternative splicing of precursor messenger RNA is an important determinant of gene expression and has a prominent role in the development and homeostasis of immune cells. …”
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Developing bioinformatics tools for the study of alternative splicing in eukaryotic genes by Lim, Yun Ping

“…Alternative splicing (AS) is a process that produces more than one protein isoform per gene in eukaryotes. …”
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Emerging functions of alternative splicing coupled with nonsense-mediated decay by Hamid, Fursham M., Makeyev, Eugene V.

“…Higher eukaryotes rely on AS (alternative splicing) of pre-mRNAs (mRNA precursors) to generate more than one protein product from a single gene and to regulate mRNA stability and translational activity. …”
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Identification of microRNA targets for the alternative splicing isoforms of CD46. by Teo, Zhi Lin.

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Interpretable Computational Modeling of pre-mRNA Splicing for Multiple Eukaryotic Species by McCue, Kayla M.

“…A variety of RNA sequence features influence this process, including the core splice site (SS) motifs and splicing regulatory elements (SREs), which recruit protein splicing factors. …”
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Pick one, but be quick : 5' splice sites and the problems of too many choices by Roca, Xavier, Krainer, Adrian R., Eperon, Ian C.

“…Splice site selection is fundamental to pre-mRNA splicing and the expansion of genomic coding potential. 5′ Splice sites (5′ss) are the critical elements at the 5′ end of introns and are extremely diverse, as thousands of different sequences act as bona fide 5′ss in the human transcriptome. …”
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Molecular and biochemical characterisation of human casein kinase I alpha splice variants by Yong, Thomas Joon Kin.

“…It has been shown in mammalian tissues that CKI alpha exists in two or three alternatively spliced variants (Rowles et al., 1991; Zhang et al., 1996; Kuret et al., 1997). …”
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An RRM–ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion by Collins, Katherine M., Kainov, Yaroslav A., Christodolou, Evangelos, Ray, Debashish, Morris, Quaid, Hughes, Timothy, Taylor, Ian A., Makeyev, Eugene V., Ramos, Andres

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Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro by Lotz, R, Osterburg, C, Chaikuad, A, Weber, S, Akutsu, M, Machel, AC, Beyer, U, Gebel, J, Löhr, F, Knapp, S, Dobbelstein, M, Lu, X, Dötsch, V

“…The transcription factor p63 is expressed in many different isoforms as a result of differential promoter use and splicing. Some of these isoforms have very specific physiological functions in the development and maintenance of epithelial tissues and surveillance of genetic integrity in oocytes. …”

Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5′ splice site choice by Hamid, Fursham M., Makeyev, Eugene V.

“…Alternative splicing (AS) provides a potent mechanism for increasing protein diversity and modulating gene expression levels. …”
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The representation of n-cutting site splicing languages for a single string with palindromic rule via de Bruijn graph by Mohd Ruslim, Nooradelena, Yuhani, Yusof, Mohd Sham, Mohamad

“…Yusof-Goode (Y-G) splicing system proposed by Yusof illustrates the deoxyribonucleic acid (DNA) splicing process in a luminous way, where the rule is written in a double triple notation. …”
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ZAP isoforms regulate unfolded protein response and epithelial- mesenchymal transition by Ly, Phuong Thao, Xu, Shaohai, Wirawan, Melissa, Luo, Dahai, Roca, Xavier

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Molecular features underlying neurodegeneration identified through in vitro modeling of genetically diverse parkinson’s disease patients by Lin, Lin, Göke, Jonathan, Cukuroglu, Engin, Dranias, Mark R., VanDongen, Antonius M.J., Stanton, Lawrence W.

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Exploring the Mechanical Behavior of a Traditional Japanese Joint for Flexible Structural Design by Ortea Varela, Ines

“…This research examines the mechanical behavior of a traditional Japanese joint, the Mortised Rabbeted Oblique (MRO) splice. Through computational simulations employing Finite Element Analysis (FEA), the study examines a continuous beam and an unmodified MRO splice, revealing expected behavior in the beam and unexpected tress concentration and displacement asymmetry in the splice. …”
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Experimental and analytical study of exterior beam-column joint for progressive collapse by Yap, Sim Lim.

“…The variables in test specimens will include the amount of joint transverse reinforcement and the lap splice details for column reinforcement. Monotonic loading will be applied on the sub-assemblages to simulate gravity loading on the damage structure in the lost of exterior column scenario.…”
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Analyzing the roles of human U1 snRNA variants in pre-mRNA processing. by Goh, Eling.

“…During splicing, U1 snRNP binds to a diversity of 5’ splice sites (5’ss) with its 5’ end. …”
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Seismic behavior of interior concretebeam-column joints with non-seismic and limited seismic detailing by Li, Qingyuan.

“…Column main bars lap spliced within plastic hinge regions were detrimental. …”
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Recognition of A-U and U-A base pairs in RNA duplexes by modified peptide nucleic acids by Yuan, Zhen

“…The stem loop structure present in the tau pre-mRNA splice site is crucial for the splicing process and contains two U-A base pairs. …”
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Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background by Nayak, S, Peto, TJ, Kucharski, M, Tripura, R, Callery, JJ, Quang Huy, DT, Gendrot, M, Lek, D, Nghia, HDT, van der Pluijm, RW, Dong, N, Long, LT, Vongpromek, R, Rekol, H, Hoang Chau, N, Miotto, O, Mukaka, M, Dhorda, M, von Seidlein, L, Imwong, M, Roca, X, Day, NPJ, White, NJ, Dondorp, AM

“…There is also a defined set of genes whose steady-state levels of mRNA and/or splice variants or antisense transcripts correlate with artemisinin resistance at the base level. …”