Gradient bandgap-tunable perovskite microwire arrays toward flexible color-cognitive devices by Fu, Yue, Yuan, Meng, Zhao, Yingjie, Dong, Meiqiu, Guo, Yangwu, Wang, Kui, Jin, Chunqi, Feng, Jiangang, Wu, Yuchen, Jiang, Lei

“…Furthermore, the integrated flexible color-cognitive devices are demonstrated for accurately recognizing similar colors, which can be applied in color blindness correction. The efficient color recognition performances, together with the flexible processing, open new opportunities for the on-chip integration of wearable devices based on microwire arrays.…”
Get full text

Adeno-associated virus mediated rhodopsin delivery in preventing secondary cone degeneration in rhodopsin knockout mice by Dauletbekov, D

“…<p>Rhodopsin-linked retinitis pigmentosa (RP) is the most common form of autosomal dominant RP, an inherited retinal degeneration, in which rod degeneration is followed by secondary cone loss leading to loss of vision and blindness. The overall objective of this work was to develop an optimized gene replacement therapy, delivering the rhodopsin gene for rhodopsin- linked RP and establish whether secondary cone loss can be delayed.…”

Land transport policy in Singapore : an insight into the bus service. by Ong, Pei Sin., Chia, Gina Lan Xian.

“…Considering Singapore’s most serious constrain – land scarcity, it would be wise to focus on the public transport, instead of extending roads blindly. Without a doubt, making public transport more attractive should be LTA’s top priority. …”
Get full text

Contact lens assisted imaging with integrated flexible handheld probe for glaucoma diagnosis by Hong, Jeesmond Xun Jie, Shinoj, Vengalathunadakal Kuttinarayanan, Murukeshan, Vadakke Matham, Baskaran, Mani, Aung, Tin

“…Angle closure glaucoma accounts for majority of the bilateral blindness in Asian countries such as Singapore, China, and India. …”
Get full text
Get full text

A biodegradable ocular implant for long-term suppression of intraocular pressure by Ng, Xu Wen, Liu, Kerh Lin, Veluchamy, Amutha Barathi, Lwin, Nyein Chan, Wong, Tina T., Venkatraman, Subbu Subramanian

“…Suboptimal control of the IOP leads to disease progression and eventually to blindness. Ideally, TM is delivered to the patient so that its action is both localized and sustained for 3 months or more. …”
Get full text
Get full text

Improving Student Outcomes Through Universal Design for Learning: A Case Study of Color Vision Deficiency in Learning Visual Design (S/O: 14513) by Sarif, Siti Mahfuzah, Muda, Suhaini, Mohamed, Nur Fadziana Faisal

“…Colour Vision Deficiency (CVD) or colour-blindness could be a disadvantage for learners in the Visual Design course, as colour is one of the essential components in Visual Design. …”
Get full text

Hollow microcapsules as periocular drug depot for sustained release of anti-VEGF protein by Radhakrishnan, Krishna, Vincent, Anita, Joseph, Rini Rachel, Moreno, Miguel, Dickescheid, Andreas, Agrawal, Rupesh, Venkatraman, Subbu S.

“…Diseases affecting the posterior segment of the eye such as age-related macular degeneration and diabetic retinopathy are leading causes of blindness all over the world. The current treatment regimen for such diseases involves repeated intravitreal injections of anti- Vascular Endothelial Growth Factor (VEGF) proteins. …”
Get full text

Effect of heat-producing needling technique on the local skin temperature : clinical dataset by Liao, Zehuan, Zhao, Yan

“…This randomized, subject-blinded clinical study was performed to examine the effect of heat-producing acupuncture treatment on the ST36 local skin temperature. …”
Get full text

Studies of bioactivity of proteins encapsulated in liposomes by Ho, Amelia May Teng.

“…One of the leading causes for blindness in the developed world is Age-related macular degeneration (AMD). …”
Get full text

Large simple randomized controlled trials—from drugs to medical devices: lessons from recent experience by Buccheri, S, James, S, Mafham, M, Landray, M, Melvin, T, Oldgren, J, Bulbulia, R, Bowman, L, Hoogervorst, LA, de Mheen, PJM, Juni, P, McCulloch, P, Fraser, AG

“…The obstacles are compounded for RCTs of high-risk medical devices by extra costs related to the interventional procedure that is needed to implant the device, challenges with willingness to randomize patients throughout a trial, and difficulties in ensuring proper blinding even with sham procedures. One strategy that may help is to promote the wider use of simpler and more streamlined RCTs using data that are collected routinely during healthcare delivery. …”

Assessing Risk in Implementing New Artificial Intelligence Triage Tools—How Much Risk is Reasonable in an Already Risky World? by Nord-Bronzyk, A, Savulescu, J, Ballantyne, A, Braunack-Mayer, A, Krishnaswamy, P, Lysaght, T, Ong, MEH, Liu, N, Menikoff, J, Mertens, M, Dunn, M

“…After two successful retrospective studies demonstrating SERP’s strong predictive accuracy, researchers decided that the pre-implementation randomised controlled trial (RCT) would not be feasible due to how the tool interacts with clinical judgement, complicating the blinded arm of the trial. This led them to consider other methods of testing SERP’s real-world capabilities, such as ongoing-evaluation type studies. …”

The efficacy of cognitive behavioural therapy in treating selective mutism in young children aged 4 to 10 years old: a qualitative systematic review by Ng, Benjamin Zeming, Atikah Binte Hassan, Dun, Yawen

“…Additionally, researchers should focus on the blinding of all key persons in their studies as a safeguard against biases.…”
Get full text

Detecting adversarial samples for deep neural networks through mutation testing by Tan, Kye Yen

“…It optimizes previous mutation testing method by implementing partial mutation to the statistically determined most distinguishable areas of the CNNs, instead of blindly implemented random mutations. These specific mutations in the CNNs causes changes in the output prediction which determines the inputs as adversarial. …”
Get full text

Sustained delivery of timolol maleate from liposomal nanocarriers by Ong, Leonard Chin Hui

“…According to the Glaucoma Research Foundation (2013), glaucoma is the world’s second leading cause of blindness. Current treatment modality includes the use of topical daily eye drops; however this mode of administration has many shortcomings. …”
Get full text

Data analystics for earthquake social tweets using clustering approach by Wang, Lanlan

“…Due to natural disasters cause great losses to human beings, giving assistances to earthquake-stricken areas blindly is a waste of resources. This thesis aims to study earthquake social tweets data for understanding the patterns of people's concerns on the ground through clustering approaches. …”
Get full text

Cache refinement type for side-channel detection of cryptographic software by Jiang, Ke, Bao, Yuyan, Wang, Shuai, Liu, Zhibo, Zhang, Tianwei

“…It reveals several significant and effective enhancements with refined types, including bit-level granularity tracking, distinguishing different effects of variables, precise type inferences, and high scalability. (2) CaType is the first static analyzer for crypto libraries in consideration of blinding-based defenses. (3) From the perspective of implementation, CaType uses cache layouts of potential vulnerable control-flow branches rather than cache states to suppress false positives. …”
Get full text

Dose response effect of carbohydrate mouth rinse on 10 km running time trial by Muhammad Saufy Abdul Karim

“…Methods: In this double-blinded, randomized, counterbalanced cross-over study, nine recreationally active and healthy men [mean age 23.78 (SD 1.39) years] completed three 10 km running sessions on the treadmill at a self-selected pace. …”
Get full text

Mine yOur owN Anatomy: revisiting medical image segmentation with extremely limited labels by You, C, Dai, W, Liu, F, Min, Y, Dvornek, NC, Li, X, Clifton, DA, Staib, L, Duncan, JS

“…However, they face three common pitfalls: (1) tailness: medical image data usually follows an implicit long-tail class distribution. Blindly leveraging all pixels in training hence can lead to the data imbalance issues, and cause deteriorated performance; (2) consistency: it remains unclear whether a segmentation model has learned meaningful and yet consistent anatomical features due to the intra-class variations between different anatomical features; and (3) diversity: the intra-slice correlations within the entire dataset have received significantly less attention. …”

Low-dose spironolactone and cardiovascular outcomes in moderate stage chronic kidney disease: a randomized controlled trial by Hobbs, FDR, McManus, RJ, Taylor, CJ, Jones, NR, Rahman, JK, Wolstenholme, J, Kim, S, Kwon, J, Jones, L, Hirst, JA, Yu, L-M, Mort, S

“…In this prospective, randomized, open, blinded endpoint trial, we assessed the effectiveness of 25 mg spironolactone in addition to usual care or usual care alone for reducing cardiovascular outcomes in stage 3b CKD among an older community cohort (mean age = 74.8 years and s.d. = 8.1). …”

Zinc absorption from maize-based meals enriched with edible house crickets: a randomized crossover stable-isotope study in Kenyan pre-school children by Hilaj, N, Boit, T, Andang’o, P, Zeder, C, Mwangi, MN, Hummel, M, Velazco, ON, van Loon, JJA, Dicke, M, Zimmermann, MB, Melse-Boonstra, A

“…We investigated zinc absorption from house crickets (Acheta domesticus) in a single-center and single-blinded cross-over study with children aged 24–36 months old in Kenya from September-November 2021. …”