MultiDCoX: Multi-factor analysis of differential co-expression by Liany, Herty, Rajapakse, Jagath Chandana, Karuturi, R. Krishna Murthy

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Plasmid-Borne Biosynthetic Gene Clusters within a Permanently Stratified Marine Water Column by Mara, Paraskevi, Geller-McGrath, David, Suter, Elizabeth, Taylor, Gordon T., Pachiadaki, Maria G., Edgcomb, Virginia P.

“…Well-studied cases of plasmid-encoded secondary metabolic genes in marine habitats include toxin/antitoxin and antibiotic biosynthesis/resistance genes. …”
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A regulatory role for repeated decoy transcription factor binding sites in target gene expression by Lee, Tek‐Hyung, Maheshri, Narendra

“…Tandem repeats of DNA that contain transcription factor (TF) binding sites could serve as decoys, competitively binding to TFs and affecting target gene expression. Using a synthetic system in budding yeast, we demonstrate that repeated decoy sites inhibit gene expression by sequestering a transcriptional activator and converting the graded dose–response of target promoters to a sharper, sigmoidal‐like response. …”
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Oxytocin receptor gene and parental bonding modulate prefrontal responses to cries : a NIRS study by Cataldo, Ilaria, Neoh, Michelle Jin-Yee, Chew, Wei Fang, Foo, Jia Nee, Lepri, Bruno, Esposito, Gianluca

“…Evidence from the genetic field states that specific allelic variations of the oxytocin receptor gene polymorphisms regulate physiological modulation of human behavior, especially concerning responses to social cues and affiliative behaviors. …”
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Discovery of a new predominant cytosine DNA modification that is linked to gene expression in malaria parasites by Hammam, Elie, Ananda, Guruprasad, Sinha, Ameya, Scheidig-Benatar, Christine, Bohec, Mylene, Preiser, Peter Rainer, Dedon, Peter C., Scherf, Artur, Vembar, Shruthi S.

“…Moreover, levels of the 5hmC-like base in gene bodies positively correlated to transcript levels, with more than 2000 genes stably marked with this modification throughout asexual development. …”
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Northern gene flow into southeastern East Asians inferred from genome-wide array genotyping by He, Guang-Lin, Li, Ying-Xiang, Zou, Xing, Yeh, Hui-Yuan, Tang, Ren-Kuan, Wang, Pei-Xin, Bai, Jing-Ya, Yang, Xiao-Min, Wang, Zheng, Guo, Jian-Xin, Chen, Jin-Wen, Chen, Jing, Yang, Mei-Qing, Zhao, Jing, Sun, Jin, Zhu, Kong-Yang, Ma, Hao, Wang, Rui, Yang, Wen-Jiao, Hu, Rong, Wei, Lan-Hai, Hou, Yi-Ping, Wang, Meng-Ge, Chen, Gang, Wang, Chuan-Chao

“…The southeastern coastal modern East Asians are genetically similar to other southern indigenous groups as well as geographically close to Neolithic-to-Iron Age populations, but they also shared excess alleles with post-Neolithic Yellow River ancients, which suggested a southward gene flow on the modern southern coastal gene pool. …”
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Constrained neuro fuzzy inference methodology for explainable personalised modelling with applications on gene expression data by Singh, Balkaran, Doborjeh, Maryam, Doborjeh, Zohreh, Budhraja, Sugam, Tan, Samuel, Sumich, Alexander, Goh, Wilson, Lee, Jimmy, Lai, Edmund, Kasabov, Nikola

“…These genes are linked to cognitive ability and impulsive behaviour. …”
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Establishing edge labels for benchmarking gene co-expression networks of saccharomyces cerevisiae and homo sapiens by Antony Velankanni Jenet Princy

“…The reliance on one type of correlation to construct Gene Coexpression Networks (GCNs) using ensemble approaches hinders a comprehensive understanding of gene co-expressions. …”
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Quantum dots-siRNA nanoplexes for gene silencing in central nervous system tumor cells by Lin, Guimiao, Chen, Ting, Zou, Jinyun, Wang, Yucheng, Wang, Xiaomei, Li, Jiefeng, Huang, Qijun, Fu, Zicai, Zhao, Yingying, Lin, Marie Chia-Mi, Xu, Gaixia, Yong, Ken-Tye

“…High gene transfection efficiency (>80%) was achieved on two glioblastoma cell lines, U87 and U251. …”
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Genome-wide gene expression profiling of the Angelman syndrome mice with Ube3a mutation by Low, Daren., Chen, Ken-Shiung.

“…Pathway analysis shows that these genes are implicated in three major networks associated with signalin, nervous system development and cell death. …”
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Exploring the dynamics of gene drive mosquitoes within wild populations using an agent-based simulation by Wickramasooriya, S, Mahmood, I, Calinescu, A, Wooldridge, M, Lanzaro, G

“…Gene drive technology is emerging as a potentially powerful tool in combating vector-borne diseases – notably malaria. …”

In vivo enhancement of tumour-specific T cells via peptide–MHC-pseudotyped retroviral gene delivery by Kwong, H, Borrow, P

Developing a framework for tracking antimicrobial resistance gene movement in a persistent environmental reservoir by Mathers, AJ, Li, TJX, He, Q, Narendra, S, Stoesser, N, Eyre, DW, Walker, AS, Barry, KE, Castañeda-Barba, S, Huang, FW, Parikh, H, Kotay, S, Crook, DW, Reidys, C

“…We present a novel approach to estimate the directional movement of antimicrobial resistance via gene mobilization.…”

Multifunctional systems in synthetic biology: Single-stranded DNA signals controls precise gene activation by Ng, SH

“…Selective gene activation was achieved by using different promoters or by using inhibitors to remove undesired signals by the DNA strand displacement reaction. …”

Developing a framework for tracking antimicrobial resistance gene movement in a persistent environmental reservoir by Mathers, AJ, Li, TJX, He, Q, Narendra, S, Stoesser, N, Eyre, DW, Walker, AS, Barry, KE, Castañeda-Barba, S, Huang, FW, Parikh, H, Kotay, S, Crook, DW, Reidys, C

“…We present a novel approach to estimate the directional movement of antimicrobial resistance via gene mobilization.</p>…”

Genes for carnivory : a comparative study on the local duplication of papain-like cysteine proteases in carnivorous plants by Tan, Qiao Wen

“…Mechanisms for carnivory in carnivorous plants have been proposed to arise from defence related mechanisms and several genes have been identified from proteomic analyses thus far. …”
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Finding transcription factor binding motifs for coregulated genes by combining sequence overrepresentation with cross-species conservation by Jia, Hui., Li, Jinming.

“…Compared with the prevailing motif finding software, our method has some advantages in finding transcriptional factor binding motifs for potential coregulated genes if the gene upstream sequences of multiple closely related species are available. …”
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Recalled parental bonding interacts with oxytocin receptor gene polymorphism in modulating anxiety and avoidance in adult relationships by Cataldo, Ilaria, Bonassi, Andrea, Lepri, Bruno, Foo, Jia Nee, Setoh, Peipei, Esposito, Gianluca

“…As many factors play a role in shaping the expectations and features of social interaction, in this study, we considered the influence of parental bonding and genetic allelic variation of oxytocin receptor gene polymorphism (rs53576) over levels of experienced anxiety and avoidance in 313 young adults belonging to two different cultural contexts, namely Italy and Singapore. …”
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Nontoxic, biodegradable hyperbranched poly(β-amino ester)s for efficient siRNA delivery and gene silencing by Ooi, Ying Jie, Huang, Chongquan, Lau, Kieran, Chew, Sing Yian, Park, Jong Gu, Chan-Park, Mary B.

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A temporal cortex cell atlas highlights gene expression dynamics during human brain maturation by Steyn, C, Mishi, R, Fillmore, S, Verhoog, MB, More, J, Rohlwink, UK, Melvill, R, Butler, J, Enslin, JMN, Jacobs, M, Sauka-Spengler, T, Greco, M, Quiñones, S, Dulla, CG, Raimondo, JV, Figaji, A, Hockman, D

“…The human brain undergoes protracted postnatal maturation, guided by dynamic changes in gene expression. Most studies exploring these processes have used bulk tissue analyses, which mask cell-type-specific gene expression dynamics. …”