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Chromatin structuring factor HMGA2 controls subtelomere stability and cancer chemosensitivity
Published 2020“…The oncofetal architectural factor HMGA2, by utilizing its three DNA binding domains has been shown to bind stalled replication forks and prevent their collapse into genotoxic DNA strand breaks in fast replicating cancer cells, hESCs as well as in other heterologous yeast and bacterial cell systems. …”
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Thesis-Doctor of Philosophy