Association between poor parent-daughter relationships and the risk of hyperglycemia in pregnancy: a hospital-based prospective cohort study in Japan by Yuto Maeda, Satomi Doi, Aya Isumi, Shuhei Terada, Junichi Sugawara, Kazuhisa Maeda, Shoji Satoh, Nobuaki Mitsuda, Takeo Fujiwara

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The Association of Clinical Outcomes with Posttreatment Changes in the Relative Eosinophil Counts and Neutrophil-to-Eosinophil Ratio in Patients with Advanced Urothelial Carcinoma... by Furubayashi N, Minato A, Negishi T, Sakamoto N, Song Y, Hori Y, Tomoda T, Tamura S, Kuroiwa K, Seki N, Fujimoto N, Nakamura M

“…Nobuki Furubayashi,1 Akinori Minato,2 Takahito Negishi,1 Naotaka Sakamoto,3 Yoohyun Song,4 Yoshifumi Hori,5 Toshihisa Tomoda,6 Shingo Tamura,7 Kentaro Kuroiwa,5 Narihito Seki,4 Naohiro Fujimoto,2 Motonobu Nakamura1 1Department of Urology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan; 2Department of Urology, University of Occupational and Environmental Health, Kitakyushu, Japan; 3Department of Urology, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan; 4Department of Urology, Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, Fukuoka, Japan; 5Department of Urology, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan; 6Department of Urology, Oita Prefectural Hospital, Oita, Japan; 7Department of Medical Oncology, National Hospital Organization Kyushu Medical Center, Fukuoka, JapanCorrespondence: Nobuki FurubayashiDepartment of Urology, National Hospital Organization Kyushu Cancer Center, Notame 3-1-1, Minami-ku, Fukuoka, 811-1395, JapanTel +81-92-541-3231Fax +81-92-551-4585Email nobumduro@gmail.comBackground: To evaluate the association of clinical outcomes with posttreatment changes in the relative eosinophil count (REC) and neutrophil-to-eosinophil ratio (NER) in patients with advanced urothelial cancer (UC) treated with pembrolizumab.Materials and Methods: We retrospectively analyzed 105 patients with advanced UC who received pembrolizumab after the failure of platinum-based chemotherapy. …”
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Natural mutation in the regulatory gene (srrG) influences virulence-associated genes and enhances invasiveness in Streptococcus dysgalactiae subsp. equisimilis strains isolated fro... by Tadayoshi Ikebe, Hitoshi Otsuka, Kazuki Chiba, Yu Kazawa, Takahiro Yamaguchi, Rumi Okuno, Yoshimi Date, Mari Sasaki, Junko Isobe, Makoto Ohnishi, Yukihiro Akeda

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Prognostic Impact of Histologic Subtype and Divergent Differentiation in Patients with Metastatic Urothelial Carcinoma Treated with Enfortumab Vedotin: A Multicenter Retrospective... by Akinori Minato, Nobuki Furubayashi, Yujiro Nagata, Toshihisa Tomoda, Hiroyuki Masaoka, Yoohyun Song, Yoshifumi Hori, Keijiro Kiyoshima, Takahito Negishi, Kentaro Kuroiwa, Narihito Seki, Ikko Tomisaki, Kenichi Harada, Motonobu Nakamura, Naohiro Fujimoto

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Association of Bovine Leukemia Virus-Induced Lymphoma with BoLA-DRB3 Polymorphisms at DNA, Amino Acid, and Binding Pocket Property Levels by Chieh-Wen Lo, Shin-nosuke Takeshima, Kosuke Okada, Etsuko Saitou, Tatsuo Fujita, Yasunobu Matsumoto, Satoshi Wada, Hidetoshi Inoko, Yoko Aida

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Impact of losing adipose tissue on outcomes from PD‐1/PD‐L1 inhibitor monotherapy in non‐small cell lung cancer by Naoya Nishioka, Tateaki Naito, Taichi Miyawaki, Michitoshi Yabe, Kosei Doshita, Hiroaki Kodama, Eriko Miyawaki, Yuko Iida, Nobuaki Mamesaya, Haruki Kobayashi, Shota Omori, Ryo Ko, Kazushige Wakuda, Akira Ono, Hirotsugu Kenmotsu, Haruyasu Murakami, Koichi Takayama, Toshiaki Takahashi

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Efficacy and safety of micafungin in empiric and D-index-guided early antifungal therapy for febrile neutropenia; A subgroup analysis of the CEDMIC trial by Shun-ichi Kimura, Yoshinobu Kanda, Masaki Iino, Takahiro Fukuda, Emiko Sakaida, Tatsuo Oyake, Hiroki Yamaguchi, Shin-ichiro Fujiwara, Yumi Jo, Akinao Okamoto, Hiroyuki Fujita, Yasushi Takamatsu, Yoshio Saburi, Itaru Matsumura, Jun Yamanouchi, Souichi Shiratori, Moritaka Gotoh, Shingen Nakamura, Kazuo Tamura

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Kawasaki Disease and Vaccination: Prospective Case-Control and Case-Crossover Studies among Infants in Japan by Kenji Murata, Sagano Onoyama, Kenichiro Yamamura, Yumi Mizuno, Kenji Furuno, Keita Matsubara, Ken Hatae, Kiminori Masuda, Yuichi Nomura, Takuro Ohno, Akiko Kinumaki, Masaru Miura, Yasunari Sakai, Shouichi Ohga, Wakaba Fukushima, Junji Kishimoto, Yosikazu Nakamura, Toshiro Hara

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Diagnostic Strategy of Early Stage Pancreatic Cancer via Clinical Predictor Assessment: Clinical Indicators, Risk Factors and Imaging Findings by Ryota Sagami, Takao Sato, Kazuhiro Mizukami, Mitsuteru Motomura, Kazuhisa Okamoto, Satoshi Fukuchi, Yuichiro Otsuka, Takashi Abe, Hideki Ono, Kei Mori, Kurato Wada, Tomoyuki Iwaki, Hidefumi Nishikiori, Koichi Honda, Yuji Amano, Kazunari Murakami

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Pneumonitis associated with pembrolizumab plus chemotherapy for non-squamous non-small cell lung cancer by Daichi Fujimoto, Satoru Miura, Keisuke Tomii, Hiromitsu Sumikawa, Kenichi Yoshimura, Kazushige Wakuda, Yuko Oya, Toshihide Yokoyama, Takashi Kijima, Tetsuhiko Asao, Motohiro Tamiya, Atsushi Nakamura, Hiroshige Yoshioka, Takaaki Tokito, Shuji Murakami, Akihiro Tamiya, Hiroshi Yokouchi, Satoshi Watanabe, Ou Yamaguchi, Ryotaro Morinaga, Takayuki Jodai, Kentaro Ito, Yoshimasa Shiraishi, Yoshihito Kogure, Ryota Shibaki, Nobuyuki Yamamoto

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Weekend and off-hour effects on the incidence of cerebral palsy: contribution of consolidated perinatal care by Satoshi Toyokawa, Junichi Hasegawa, Tsuyomu Ikenoue, Yuri Asano, Emi Jojima, Shoji Satoh, Tomoaki Ikeda, Kiyotake Ichizuka, Satoru Takeda, Nanako Tamiya, Akihito Nakai, Keiya Fujimori, Tsugio Maeda, Hideaki Masuzaki, Hideaki Suzuki, Shigeru Ueda

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Efficacy and safety of add-on mirogabalin to conventional therapy for the treatment of peripheral neuropathic pain after thoracic surgery: the multicenter, randomized, open-label A... by Takuro Miyazaki, Keitaro Matsumoto, Toshihiko Sato, Isao Sano, Katsuro Furukawa, Koichiro Shimoyama, Ryotaro Kamohara, Makoto Suzuki, Masamichi Kondou, Norihiko Ikeda, Shunsuke Tabata, Kazuhito Shiosakai, Takeshi Nagayasu, on behalf of the ADMIT-NeP Study group

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High Incidence of C797S Mutation in Patients With Long Treatment History of EGFR Tyrosine Kinase Inhibitors Including Osimertinib by Atsushi Osoegawa, MD, PhD, Masafumi Yamaguchi, MD, PhD, Tomomi Nakamura, MD, PhD, Ryotaro Morinaga, MD, Kentaro Tanaka, MD, PhD, Kosuke Kashiwabara, MD, PhD, Takashi Miura, MD, PhD, Takayuki Suetsugu, MD, PhD, Taishi Harada, MD, PhD, Tatsuma Asoh, MD, PhD, Kenichi Taguchi, MD, PhD, Kazuki Nabeshima, MD, PhD, Junji Kishimoto, MA, Kazuko Sakai, PhD, Kazuto Nishio, MD, PhD, Kenji Sugio, MD, PhD

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Real-world status of treatment for lymphoid neoplasms developed during the course of myeloproliferative neoplasms in Japan by Yoko Edahiro, Tomonori Ochiai, Yoshinori Hashimoto, Michiko Ichii, Takeshi Okatani, Hiromi Omura, Kei Nakajima, Makoto Sasaki, Jun Ando, Tomoiku Takaku, Michiaki Koike, Koh Izumiyama, Junji Hiraga, Tomofumi Yano, Kensuke Usuki, Eiichi Ohtsuka, Kenji Yokoyama, Tatsuo Oyake, Naoki Takahashi, Tetsuya Nishida, Takafumi Nakao, Yasutaka Fukuda, Takashi Akasaka, Atsuko Mugitani, Miki Ando, Norio Komatsu

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Association Between Immune-Related Adverse Events and Efficacy and Changes in the Relative Eosinophil Count Among Patients with Advanced Urothelial Carcinoma Treated by Pembrolizum... by Furubayashi N, Minato A, Negishi T, Sakamoto N, Song Y, Hori Y, Tomoda T, Harada M, Tamura S, Miura A, Komori H, Kuroiwa K, Seki N, Fujimoto N, Nakamura M

“…Nobuki Furubayashi,1 Akinori Minato,2 Takahito Negishi,1 Naotaka Sakamoto,3 Yoohyun Song,4 Yoshifumi Hori,5 Toshihisa Tomoda,6 Mirii Harada,2 Shingo Tamura,7 Akihiro Miura,1 Hiroki Komori,1 Kentaro Kuroiwa,5 Narihito Seki,4 Naohiro Fujimoto,2 Motonobu Nakamura1 1Department of Urology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan; 2Department of Urology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan; 3Department of Urology, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan; 4Department of Urology, Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, Fukuoka, Japan; 5Department of Urology, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan; 6Department of Urology, Oita Prefectural Hospital, Oita, Japan; 7Department of Medical Oncology, National Hospital Organization Kyushu Medical Center, Fukuoka, JapanCorrespondence: Nobuki Furubayashi, Department of Urology, National Hospital Organization Kyushu Cancer Center, Notame 3-1-1, Minami-ku, Fukuoka, 811-1395, Japan, Tel +81-92-541-3231, Fax +81-92-551-4585, Email nobumduro@gmail.comBackground: To evaluate the association between immune-related adverse events (irAEs) and the clinical outcomes and also between irAEs and the post-treatment changes in the relative eosinophil count (REC) in advanced urothelial carcinoma (UC) patients treated with pembrolizumab.Materials and Methods: This retrospective study analyzed 105 advanced UC patients treated with pembrolizumab after disease progression on platinum-based chemotherapy between January 2018 and June 2021. …”
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First evidence of tick-borne encephalitis (TBE) outside of Hokkaido Island in Japan by Masayuki Ohira, Kentaro Yoshii, Yasuhiro Aso, Hideto Nakajima, Toru Yamashita, Ikuko Takahashi-Iwata, Norihisa Maeda, Katsuro Shindo, Toshihiko Suenaga, Tohru Matsuura, Kazuma Sugie, Tadanori Hamano, Akira Arai, Rikiya Furutani, Yasuhiro Suzuki, Chikako Kaneko, Yasuhiro Kobayashi, Eduardo Campos-Alberto, Lisa R. Harper, Juanita Edwards, Cody Bender, Andreas Pilz, Shuhei Ito, Frederick J. Angulo, Wilhelm Erber, Harish Madhava, Jennifer Moïsi, Luis Jodar, Hidehiro Mizusawa, Masaki Takao

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A Real-World Study on the Effectiveness and Safety of Pembrolizumab Plus Chemotherapy for Nonsquamous NSCLC by Daichi Fujimoto, MD, Satoru Miura, MD, PhD, Kenichi Yoshimura, MD, PhD, Kazushige Wakuda, MD, Yuko Oya, MD, Koji Haratani, MD, PhD, Shoichi Itoh, MD, Takehiro Uemura, MD, PhD, Ryotaro Morinaga, MD, PhD, Takayuki Takahama, MD, PhD, Kazuhisa Nakashima, MD, Motoko Tachihara, MD, PhD, Go Saito, MD, Junko Tanizaki, MD, PhD, Kohei Otsubo, MD, PhD, Satoshi Ikeda, MD, Hirotaka Matsumoto, MD, Satoshi Hara, MD, Akito Hata, MD, Takeshi Masuda, MD, PhD, Nobuyuki Yamamoto, MD, PhD

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Severe pediatric acute encephalopathy syndromes related to SARS-CoV-2 by Hiroshi Sakuma, Jun-ichi Takanashi, Kazuhiro Muramatsu, Hidehito Kondo, Takashi Shiihara, Motomasa Suzuki, Kazuo Okanari, Mariko Kasai, Osamu Mitani, Tomoyuki Nakazawa, Taku Omata, Konomi Shimoda, Yuichi Abe, Yoshihiro Maegaki, Kei Murayama, Yuka Murofushi, Hiroaki Nagase, Akihisa Okumura, Yasunari Sakai, Hiroko Tada, Hiroko Tada, Masashi Mizuguchi, Japanese Pediatric Neuro-COVID-19 Study Group, Tsuyoshi Matsuoka, Hiroshi Oakada, Tatsuharu Sato, Kenjiro Kikuchi, Satoshi Akamine, Nanako Kawata, Shinichiro Morichi, Hideyuki Iwayama, Ryuta Tanaka, Yoshiyuki Hanaoka, Yuki Minamisawa, Tatsuya Ema, Mitsuo Motobayashi, Tomoshiro Ito, Fumikazu Sano

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