The Role of Epigenetics in the Induction of Fetal Hemoglobin: A Combination Therapy Approach by Mohammad Ahmadvand, Mehrdad Noruzinia, Ali Dehghani Fard, Mostafa Montazer Zohour, Mohammad Amin Tabatabaiefar, Masoud Soleimani, Saeid Kaviani, Saeid Abroun, Sahar Beiranvand, Najmaldin Saki

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Induction of HBF by Mehran Karimi, Nader Cohan

Subjects: “…HbF inducer, hemoglobinopathy, γ-globin gene, re-activation.…”
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The Long Scientific Journey of Sirolimus (Rapamycin): From the Soil of Easter Island (Rapa Nui) to Applied Research and Clinical Trials on β-Thalassemia and Other Hemoglobinopathie... by Roberto Gambari, Cristina Zuccato, Lucia Carmela Cosenza, Matteo Zurlo, Jessica Gasparello, Alessia Finotti, Maria Rita Gamberini, Marco Prosdocimi

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The Effect of Resveratrol on Gamma Globin Gene Expression in Patients with Beta Thalassemia: The Role of Adaptation to Cellular Stress by Hossein Jalali, Mohammad Reza Mahdavi, Mehrnoush Kosaryan, Ahmad Najafi, Aily Aliasgharian, Ebrahim Salehifar

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Clinical genome editing to treat sickle cell disease—A brief update by Parinaz Zarghamian, Parinaz Zarghamian, Parinaz Zarghamian, Julia Klermund, Julia Klermund, Toni Cathomen, Toni Cathomen

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Characterization of the transcriptome profiles related to globin gene switching during <it>in vitro </it>erythroid maturation by Li Biaoru, Ding Lianghao, Li Wei, Story Michael D, Pace Betty S

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Gamma reactivation using the spongy effect of KLF1-binding site sequence: an approach in gene therapy for beta-thalassemia by Nasrin Heydari, Laleh Shariati, Hossein Khanahmad, Zahra Hejazi, Mansoureh Shahbazi, Mansoor Salehi

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Pharmacological Induction of Fetal Hemoglobin in β-Thalassemia and Sickle Cell Disease: An Updated Perspective by Rayan Bou-Fakhredin, Lucia De Franceschi, Irene Motta, Maria Domenica Cappellini, Ali T. Taher

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Activation of γ-globin expression by LncRNA-mediated ERF promoter hypermethylation in β-thalassemia by Xiuqin Bao, Yuanyi Gao, Zhongju Wang, Yuhua Ye, Diyu Chen, Yangjin Zuo, Cunyou Zhao, Xiangmin Xu

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The Optimized γ-Globin Lentiviral Vector GGHI-mB-3D Leads to Nearly Therapeutic HbF Levels In Vitro in CD34⁺ Cells from Sickle Cell Disease Patients by Ekati Drakopoulou, Maria Georgomanoli, Carsten W. Lederer, Fottes Panetsos, Marina Kleanthous, Ersi Voskaridou, Dimitrios Valakos, Eleni Papanikolaou, Nicholas P. Anagnou

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MicroRNA-92a-3p-mediated inhibition of BCL11A upregulates γ-globin expression and inhibits oxidative stress and apoptosis in erythroid precursor cells by Huili Li, Ruoping Lin, Huan Li, Rilan Ou, Kaiping Wang, Junrong Lin, Chunfu Li

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CRISPR Gene Therapy: A Promising One-Time Therapeutic Approach for Transfusion-Dependent β-Thalassemia—CRISPR-Cas9 Gene Editing for β-Thalassemia by Udani Gamage, Kesari Warnakulasuriya, Sonali Hansika, Gayathri N. Silva

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miR-365-3p mediates BCL11A and SOX6 erythroid-specific coregulation: A new player in HbF activation by Michela Simbula, Maria Francesca Manchinu, Maura Mingoia, Mauro Pala, Isadora Asunis, Cristian Antonio Caria, Lucia Perseu, Manan Shah, Merlin Crossley, Paolo Moi, Maria Serafina Ristaldi

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