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    Altered Extended Locus Coeruleus and Ventral Tegmental Area Networks in Boys with Autism Spectrum Disorders: A Resting-State Functional Connectivity Study by Huang Y, Yu S, Wilson G, Park J, Cheng M, Kong X, Lu T, Kong J

    Published 2021-04-01
    “…Yiting Huang,1,2 Siyi Yu,2 Georgia Wilson,2 Joel Park,2 Ming Cheng,2 Xuejun Kong,3 Tao Lu,1 Jian Kong2 1School of Life Sciences, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; 3Martino Imaging Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USACorrespondence: Tao LuSchool of Life Sciences, Beijing University of Chinese Medicine, No. 11 East Road, North 3rd Ring Road, Beijing, 100029, People’s Republic of ChinaEmail taolu@bucm.edu.cnJian KongDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 120 2nd Ave, Room 101C, Charlestown, MA, 02129, USAEmail jkong2@mgh.harvard.eduIntroduction: Previous studies have suggested that cerebral projections of the norepinephrine (NE) and dopamine (DA) systems have important etiology and treatment implications for autism spectrum disorder (ASD).Methods: We used functional magnetic resonance imaging to evaluate spontaneous resting state functional connectivity in boys aged 7– 15 years with ASD (n=86) and age-, intelligence quotient-matched typically developing boys (TD, n=118). …”
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