Mortalidad por causas violentas en adolescentes y jóvenes: un desafio para la Región de las Américas Mortality from violent causes in adolescents and young people: a challenge for... by João Yunes, Tamara Zubarew

“…Los países con mayores tasa de mortalidad por homicidio entre los varones de 15 a 19 años son, en orden decreciente: Colombia, El Salvador, Puerto Rico, Venezuela y Brasil. Los varones de 20 a 24 años presentan las tasas mas altas de homicidio dentro de los grupos estudiados. …”
Get full text

Disparités socioéconomiques et spatiales dans les décès attribuables au suicide chez les jeunes et aux blessures non intentionnelles en Colombie-Britannique (2009-2013) by Moe Zandy, Li Rita Zhang, Diana Kao, Fahra Rajabali, Kate Turcotte, Alex Zheng, Megan Oakey, Kate Smolina, Ian Pike, Drona Rasali

“…Nous avons jumelé les données liées aux décès (2009 à 2013) tirées des statistiques de l’état civil et des données socioéconomiques de CensusPlus de 2011 à l’échelle de l’aire de diffusion ou de la circonscription sanitaire afin d'étudier les taux de mortalité normalisés selon l’âge (TMNA) et les disparités des TMNA concernant les blessures non intentionnelles et leurs sous-types, notamment les blessures liées aux chutes chez les aînés (65 ans et plus) et les blessures liées au transport, ainsi que le suicide chez les jeunes (15 à 24 ans), ce dernier étant considéré comme une forme de blessure intentionnelle. …”
Get full text

Urine transferrin as an early endothelial dysfunction marker in type 2 diabetic patients without nephropathy: a case control study by José Juan Sánchez-Hidalgo, Juan Antonio Suárez-Cuenca, José Juan Lozano-Nuevo, Víctor Hugo García-López, María Graciela Leal-Gutiérrez, Sein Antonio León-Angel, María Leslye Ramírez-Villa, Martha Elena Rodea-Rubio, José Enrique González-Hernández, José Antonio Canela-Mayoral, Eduardo Murillo-Heredia, Eduardo Vera-Gómez, Alejandro Hernández-Patricio, Carlos Ramiro Zamora-Alemán, Gabriela Alexandra Domínguez-Pérez, Juan Ariel Gutiérrez-Buendia, Paul Mondragón-Terán

“…Transferrin has a molecular weight comparable to albumin, whereas transferrinuria and microalbuminuria in a 24-h urine sample may comparably reflect early diabetic nephropathy. …”
Get full text

PRIMARY MEDIASTINAL B-CELL LYMPHOMA IN BRAZIL: INTENSIFIED REGIMEN DOESN'T SEEM TO IMPROVE OUTCOMES WHEN COMPARED TO R-CHOP IN A RESOURCE-CONSTRAINED SCENARIO – A RETROSPECTIVE CHA... by RD Velasques, WF Silva-Júnior, M Bellesso, V Rocha, J Pereira

Get full text

Evaluating the performance of Plasmodium falciparum genetic metrics for inferring National Malaria Control Programme reported incidence in Senegal by Wesley Wong, Stephen F. Schaffner, Julie Thwing, Mame Cheikh Seck, Jules Gomis, Younouss Diedhiou, Ngayo Sy, Medoune Ndiop, Fatou Ba, Ibrahima Diallo, Doudou Sene, Mamadou Alpha Diallo, Yaye Die Ndiaye, Mouhamad Sy, Aita Sene, Djiby Sow, Baba Dieye, Abdoulaye Tine, Jessica Ribado, Joshua Suresh, Albert Lee, Katherine E. Battle, Joshua L. Proctor, Caitlin A. Bever, Bronwyn MacInnis, Daouda Ndiaye, Daniel L. Hartl, Dyann F. Wirth, Sarah K. Volkman

“…Samples were genotyped with a 24 single nucleotide polymorphism (SNP) molecular barcode that detects parasite strains, distinguishes polygenomic (multiple strain) from monogenomic (single strain) infections, and identifies clonal infections. …”
Get full text

A protein- and fiber-rich diet with astaxanthin alleviates high-fat diet-induced obesity in beagles by Jinhua Xue, Jinhua Xue, Yuanyuan Lu, Toujun Zou, Wei Shi, Shuang Wang, Xu Cheng, Juan Wan, Yun Chen, Min Wang, Qingzheng Wang, Qingzheng Wang, Xia Yang, Mingxing Ding, Zhili Qi, Yi Ding, Manli Hu, Xin Zhang, Hongliang Li, Hongliang Li, Hongliang Li, Yufeng Hu

“…We systemically evaluated global influences of the designed weight-loss diet on metabolic homeostasis in an obese beagle model.Materials and methodsBeagles were induced for obesity by a 24-week HFD treatment and then included into weight-loss programs. …”
Get full text

The species-level microbiota of healthy eyes revealed by the integration of metataxonomics with culturomics and genome analysis by Kui Dong, Kui Dong, Ji Pu, Jing Yang, Guohong Zhou, Xuan Ji, Xuan Ji, Zhiming Kang, Juan Li, Min Yuan, Xiaoling Ning, Zhaoxia Zhang, XingYu Ma, Yanpeng Cheng, Yanpeng Cheng, Hong Li, Qin Ma, Hong Li, Lijun Zhao, Wenjing Lei, Bin Sun, Jianguo Xu, Jianguo Xu, Jianguo Xu

Get full text

Use of tofacitinib in real clinical practice to treat patients with rheumatoid arthritis resistant to synthetic and biological disease-modifying antirheumatic drugs: Results of a m... by D. E. Karateev, D. E. Abdulganieva, A. R. Babaeva, A. A. Baranov, L. P. Evstigneeva, O. N. Ivanova, G. V. Lukina, E. L. Luchikhina, V. I. Mazurov, A. S. Misiyuk, O. V. Semagina, A. E. Sizikov, V. N. Sorotskaya

“…A total of 93 (92.1%) of the 101 patients completed a 24-week period of the investigation. 8 (7.9%) patients prematurely discontinued TOFA after an average of 2.75±0.71 months. …”
Get full text

Real-World Safety and Effectiveness of Omalizumab in Moderate to Severe Allergic Asthma Patients in China: A Post-Authorization Study by Su N, Zhi L, Liu F, Wang Y, Zhang Q, Liu X, Wang X, Hao G, Zhang X, Hu Q, Ligueros-Saylan M, Uddin A, Yang J, Liang T, Ding L, Li R, Wang C

“…In accordance with the Chinese Health Authority requirement, the post-authorization safety study (PASS) was conducted to evaluate the safety and effectiveness of omalizumab in a real-world setting in patients with moderate to severe allergic asthma in China over a 24-week observation period.Patients and Methods: This is a single-arm, non-interventional, multicenter, PASS conducted in adult, adolescent, and pediatric patients (≥ 6 years old) with moderate to severe allergic asthma receiving omalizumab in a real-world clinical setting from 2020 to 2021 in 59 sites of mainland China.Results: In total, 1546 patients were screened and 1528 were enrolled. …”
Get full text

Does food biodiversity protect against malnutrition and favour the resilience to climate change-related events in Amazon Indigenous communities? A protocol for a mixed methods stud... by Rogelia Pizango-Inuma, Manuel Pizango-Tangoa, Jorge Velez-Quevedo, Junior Chanchari-Huiñapi, Teresita Antazu, Nerita Inuma-Tangoa, Juan Pablo Aparco, Marianella Miranda-Cuadros, Manuela Verastegui, Pedro Aro-Guardia, Tiana Bressan, Valeria Morales-Ancajima, J. Jaime Miranda, Janet Cade, Carol Zavaleta-Cortijo, Darren C. Greenwood, James Ford, Rosa Silvera-Ccallo, Cesar Carcamo, Guillermo Lancha-Rucoba, Connie Fernandez-Neyra

“…FBD will be measured with a food frequency questionnaire and a 24-hour dietary recall. Soil-transmitted helminth infections, malaria, and inflammatory biomarkers will also be evaluated. …”
Get full text

Embryonic development and larval stages of Steindachneridion parahybae (Siluriformes: Pimelodidae): implications for the conservation and rearing of this endangered Neotropical spe... by Renato M. Honji, Carlos E. Tolussi, Paulo H. Mello, Danilo Caneppele, Renata G. Moreira

“…Reprodutores foram artificialmente induzidos à reprodução e a extrusão ocorreu com 200-255 horas-graus após a indução hormonal a 24°C. A ontogenia larval foi avaliada a cada 10 minutos sob microscópio/ estereomicroscópio, utilizando-se amostras de ovos recém coletados. …”
Get full text

DRR Dhan 58, a Seedling Stage Salinity Tolerant NIL of Improved Samba Mahsuri Shows Superior Performance in Multi-location Trials by G. Rekha, V. Abhilash Kumar, C. G. Gokulan, M. B. V. N. Koushik, B. Laxmi Prasanna, Swapnil Kulkarni, D. Aleena, G. Harika, S. K. Hajira, K. Pranathi, E. Punniakoti, R. R. Kale, T. Dilip Kumar, D. Ayyappa, M. Anila, Pragya Sinha, K. K. Manohara, G. Padmavathi, L. V. Subba Rao, G. S. Laha, M. S. Srinivas Prasad, R. A. Fiyaz, K. Suneetha, S. M. Balachandran, Hitendra Kumar Patel, Ramesh V. Sonti, P. Senguttuvel, R. M. Sundaram

“…Conclusion DRR Dhan 58, possessing Saltol and three bacterial blight resistance genes (Xa21, xa13 and xa5) in the genetic background of the Indian mega-variety of rice, Samba Mahsuri, was developed for potential cultivation in areas prone to seedling stage salinity, as well as areas with endemic bacterial blight disease. This entry had a 24% yield advantage over the recurrent parent ISM under coastal saline conditions in multi-location trials and was recently released for commercial cultivation in India.…”
Get full text

Importância da proteína C-reativa no diagnóstico e no prognóstico intra-hospitalar em pacientes com dor torácica na sala de emergência C-reactive protein diagnostic and prognostic... by Alfredo Antonio Potsch, Aristarco Gonçalves Siqueira Filho, Bernardo Rangel Tura, Roberto Gamarski, Roberto Bassan, Mônica Viegas Nogueira, Marco Aurélio E. Moutinho, Antônio Cláudio Masetto Silva, Humberto Villacorta, Augusta Leite Campos

Get full text

The Structural Equation Model of Political Behaviors on Organizational Citizenship Behavior with the Mediation of job Engagement and Job Satisfaction Behavior in the Companies Affi... by Siroos Ghanbari, Saeid Norollahee

“…Organizational citizenship behavior was measured with a 24-item questionnaire by Podsakoff et al (1990). …”
Get full text

Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study by Akram Imam, Eva C. Winnebeck, Nina Buchholz, Philippe Froguel, Philippe Froguel, Amélie Bonnefond, Amélie Bonnefond, Michele Solimena, Anna Ivanova, Michel Bouvier, Bianca Plouffe, Bianca Plouffe, Guillaume Charpentier, Angeliki Karamitri, Ralf Jockers, Till Roenneberg, Céline Vetter, Céline Vetter

“…Secondary analyses also compare T2D MT2 to 15 healthy controls.ResultsPatients with rare MT2 mutations had a later sleep onset (MD = 1.23, 95%CI = 0.42;2.04), and midsleep time (MD = 0.91, 95%CI = 0.12;1.70), slept more irregularly (MD in SRI = −8.98, 95%CI = −16.36;−1.60), had higher levels of behavioral circadian misalignment (MD in CPD = 1.21, 95%CI = 0.51;1.92), were more variable in regard to duration between first caloric intake and average sleep offset (MD = 1.08, 95%CI = 0.07;2.08), and had more caloric episodes in a 24 h day (MD = 1.08, 95%CI = 0.26;1.90), in comparison to T2D controls. …”
Get full text

Influence of activation modes on diametral tensile strength of dual-curing resin cements Influência dos métodos de ativação na resistência à tração diametral de cimentos resinosos... by Renata Garcia Fonseca, Juliana Gomes dos Santos, Gelson Luis Adabo

“…Cements were either: 1) not exposed to light (chemical activation = self-cured groups) or 2) photoactivated through mylar strips (chemical and photo-activation = dual-cured groups) (n = 10). After a 24 h storage in 37ºC distilled water, specimens were subjected to compressive load in a testing machine. …”
Get full text

Addition of dexmedetomidine to bupivacaine in ultrasonography-guided paravertebral blockade potentiates postoperative pain relief among patients undergoing thoracotomy by Cihangir Biçer, Esra Nur Ünalan, Recep Aksu, Ömer Önal, Işın Güneş

Get full text

Efficacy and Safety of Multiple Dosages of Fostamatinib in Adult Patients With Rheumatoid Arthritis: A Systematic Review and Meta-Analysis by Yaqi Kang, Xinrui Jiang, Dalian Qin, Dalian Qin, Long Wang, Long Wang, Jing Yang, Jing Yang, Anguo Wu, Anguo Wu, Feihong Huang, Feihong Huang, Yun Ye, Yun Ye, Jianming Wu, Jianming Wu, Jianming Wu

“…Furthermore, 100 mg bid can be considered the most beneficial regimen over a 24-week period. More data are however needed to clarify the incidence of other adverse events and serious adverse reactions.…”
Get full text

Determinación e interpretación de calidad de agua destinada a uso ganadero by Ignacio Tuells, Nelson Erviti

“…Respecto a los iones sulfatos siete muestras presentan menos de 0,250 g.L-1; tres están entre más de 0,250 y menos de 1,00 g.L-1; tres entre más de 1,00 a 1,7 g.L-1; dos entre 1,7 a 2,4 g.L-1 y dos entre 3,0 y 3,7 g.L-1. En tres muestras no se detectó arsénico, otras presentaron contenidos inferiores a 0,25 ppm y se hallaron en 3 muestras concentraciones respectivas de 0,3; 0,5 y 1,5 ppm. …”
Get full text

Superior gluteal nerve: a new block on the block? by Miguel Sá, Rita Graça, Hugo Reis, José Miguel Cardoso, José Sampaio, Célia Pinheiro, Duarte Machado

Get full text