1,4-Disubstituted-1,2,3-Triazole Compounds Induce Ultrastructural Alterations in <i>Leishmania amazonensis</i> Promastigote: An in Vitro Antileishmanial and in Silico Pharmacokinet... by Fernando Almeida-Souza, Verônica Diniz da Silva, Gabriel Xavier Silva, Noemi Nosomi Taniwaki, Daiana de Jesus Hardoim, Camilla Djenne Buarque, Ana Lucia Abreu-Silva, Kátia da Silva Calabrese

Subjects: Get full text

Pharmacokinetics, Tissue Distribution, Metabolism, and Excretion of Naringin in Aged Rats by Xuan Zeng, Weiwei Su, Yuying Zheng, Yudong He, Yan He, Hongyu Rao, Wei Peng, Hongliang Yao

Subjects: Get full text

New N-Alkylated Heterocyclic Compounds as Prospective NDM1 Inhibitors: Investigation of In Vitro and In Silico Properties by Yassine Kaddouri, Btissam Bouchal, Farid Abrigach, Mohamed El Kodadi, Mohammed Bellaoui, Ahmed Elkamhawy, Rachid Touzani, Magda H. Abdellattif

Subjects: Get full text

Editorial: Drug-drug interactions in pharmacology by Simona Pichini, Annagiulia Di Trana, Oscar García-Algar, Francesco Paolo Busardò

Subjects: Get full text

Novel quinazolines bearing 1,3,4-thiadiazole-aryl urea derivative as anticancer agents: design, synthesis, molecular docking, DFT and bioactivity evaluations by Sara Masoudinia, Marjaneh Samadizadeh, Maliheh Safavi, Hamid Reza Bijanzadeh, Alireza Foroumadi

Subjects: Get full text

Reinvigorate the synthesis, spectroscopic findings, SEM morphology investigation, and antimicrobial silhouette of contemporary Salen ligands: A comprehensive DFT landscape by Dhrubajyoti Majumdar, Jessica Elizabeth Philip, Sourav Roy, Burak Tüzün

Subjects: Get full text

Derivatives of Betulin and Betulinic Acid Containing a Phosphonate Group—In Silico Studies and Preliminary In Vitro Assessment of Antiviral Activity by Ewa Bębenek, Paweł Pęcak, Monika Kadela-Tomanek, Beata Orzechowska, Elwira Chrobak

Subjects: Get full text

Combining Human Genetics of Multiple Sclerosis with Oxidative Stress Phenotype for Drug Repositioning by Stefania Olla, Maristella Steri, Alessia Formato, Michael B. Whalen, Silvia Corbisiero, Cristina Agresti

Subjects: Get full text

Design, Synthesis, and Biological Evaluation of Pyridazinones Containing the (2-Fluorophenyl) Piperazine Moiety as Selective MAO-B Inhibitors by Muhammed Çeçen, Jong Min Oh, Zeynep Özdemir, Saliha Ebru Büyüktuncel, Mehtap Uysal, Mohamed A. Abdelgawad, Arafa Musa, Nicola Gambacorta, Orazio Nicolotti, Bijo Mathew, Hoon Kim

Subjects: Get full text

Design, Synthesis and Studies of Novel Imidazoles by Priyanka Chandra, Swastika Ganguly, Manik Ghosh

Subjects: Get full text

Galantamine-Curcumin Hybrids as Dual-Site Binding Acetylcholinesterase Inhibitors by Georgi Stavrakov, Irena Philipova, Atanas Lukarski, Mariyana Atanasova, Dimitrina Zheleva, Zvetanka D. Zhivkova, Stefan Ivanov, Teodora Atanasova, Spiro Konstantinov, Irini Doytchinova

Subjects: Get full text

Synthesis, Characterization, DFT, and In Silico Investigation of Two Newly Synthesized β-Diketone Derivatives as Potent COX-2 Inhibitors by Malahat Musrat Kurbanova, Abel Mammadali Maharramov, Arzu Zabit Sadigova, Fidan Zaur Gurbanova, Suraj Narayan Mali, Rashad Al-Salahi, Youness El Bakri, Chin-Hung Lai

Subjects: Get full text

In silico approaches of gandarusa (Justicia gendarussa Burm. f.) potential for osteoporosis prevention via EGF pathway by Sri Dinengsih, Nurdiana, Sri Winarsih, Bambang Raharjo, Agustina Tri Endharti

Subjects: Get full text

Investigation of plant metabolites as potential inhibitors of Acinetobacter baumannii: An In-Silico approach by Jamil Ahmed, Nabioun Haque, Saklayeen Mahfuz, Tanjin Barketullah Robin, Md Razwan Sardar Sami, Md Maruf Raihan, Hafsa Akter, Md Nazmul Islam Bappy

Subjects: Get full text

Enzymatically Modified Isoquercitrin: Production, Metabolism, Bioavailability, Toxicity, Pharmacology, and Related Molecular Mechanisms by Aleksandra Owczarek-Januszkiewicz, Anna Magiera, Monika Anna Olszewska

Subjects: Get full text

Advanced design technology : selected papers from 2011 international conference on advanced design and manufacturing engineering (ADME 2011), 16-18 September, 2011, Guangzhou, China / by Gao, Jian

Evaluation of Alectinib Metabolic Stability in HLMs Using Fast LC-MS/MS Method: In Silico ADME Profile, P450 Metabolic Lability, and Toxic Alerts Screening by Mohamed W. Attwa, Haitham AlRabiah, Gamal A. E. Mostafa, Adnan A. Kadi

Subjects: Get full text

One-Pot Multicomponent Synthesis of Methoxybenzo[<i>h</i>]quinoline-3-carbonitrile Derivatives; Anti-Chagas, X-ray, and In Silico ADME/Tox Profiling Studies by Hegira Ramírez, Katiuska Charris, Esteban Fernandez-Moreira, Benjamín Nogueda-Torres, Mario V. Capparelli, Jorge Ángel, Jaime Charris

“…A study in silico on absorption, distribution, metabolism, excretion, and toxicity (ADME/Tox) profiling to help describe the molecular properties related to the pharmacokinetic aspects in the human body of these compounds was reported. …”
Get full text

Synthesis, Characterization, ADME Study and Anti-proliferative evaluation against MCF-7 breast cancer cell line of new analog of a 4-aminophenyl quinazolinone derivative by Zainab A. Jabbar, Monther F. Mahdi, Basma M.Abd Razik

Get full text

Perancangan Arsitektur Perusahaan Sistem Informasi Sertifikasi (SIS) Menggunakan Kerangka Kerja TOGAF ADM Pada Balai Besar Teknologi Pencegahan Pencemaran Industri (BBTPPI) Semarang by Adhitya Pradipta, Candra Irawan

“…Using the TOGAF ADM framework is expected to solve existing problems and can produce blueprints of IT to produce integrated system information and can also be used for further research materials. …”
Get full text