Elevated Pressure Increases Ca2+ Influx Through AMPA Receptors in Select Populations of Retinal Ganglion Cells by Xiangyi Wen, Xiangyi Wen, Asia L. Cahill, Cody Barta, Wallace B. Thoreson, Wallace B. Thoreson, Scott Nawy, Scott Nawy

Subjects: “…AMPA receptor…”
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Dysregulation of AMPA Receptor Trafficking and Intracellular Vesicular Sorting in the Prefrontal Cortex of Dopamine Transporter Knock-Out Rats by Giorgia Targa, Francesca Mottarlini, Beatrice Rizzi, Damiana Leo, Lucia Caffino, Fabio Fumagalli

“…Moreover, the reduced expression of AMPA receptor-specific anchoring proteins and structural markers, such as Neuroligin-1 and nCadherin, likely indicate a pattern of synaptic instability. …”
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GSG1L-containing AMPA receptor complexes are defined by their spatiotemporal expression, native interactome and allosteric sites by Amanda M. Perozzo, Jochen Schwenk, Aichurok Kamalova, Terunaga Nakagawa, Bernd Fakler, Derek Bowie

“…Abstract Transmembrane AMPA receptor regulatory proteins (TARPs) and germ cell-specific gene 1-like protein (GSG1L) are claudin-type AMPA receptor (AMPAR) auxiliary subunits that profoundly regulate glutamatergic synapse strength and plasticity. …”
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Regulated RalBP1 Binding to RalA and PSD-95 Controls AMPA Receptor Endocytosis and LTD by Han, Kihoon, Kim, Myoung-Hwan, Seeburg, Daniel P., Seo, Jinsoo, Verpelli, Chiara, Han, Seungnam, Chung, Hye Sun, Ko, Jaewon, Lee, Hyun Woo, Kim, Karam, Heo, Won Do, Meyer, Tobias, Kim, Hyun, Sala, Carlo, Choi, Se-Young, Sheng, Morgan Hwa-Tze, Kim, Eunjoon

“…NMDA receptor (NMDAR)–dependent LTD, an extensively studied form of LTD, involves the endocytosis of AMPA receptors (AMPARs) via protein dephosphorylation, but the underlying mechanism has remained unclear. …”
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Effect of chronic electroconvulsive shock and antidepressant drugs on mRNA expression of AMPA receptor subunits in the rat brain by Pei, Q, Bullard, E, Sprakes, M, Zetterstrom, T, Sharp, T

A pathway-specific function for different AMPA receptor subunits in amygdala long-term potentiation and fear conditioning. by Humeau, Y, Reisel, D, Johnson, A, Borchardt, T, Jensen, V, Gebhardt, C, Bosch, V, Gass, P, Bannerman, D, Good, M, Hvalby, Ø, Sprengel, R, Lüthi, A

“…The AMPA receptor subunit glutamate receptor 1 (GluR1 or GluR-A) contributes to amygdala-dependent emotional learning. …”

GluA4 facilitates cerebellar expansion coding and enables associative memory formation by Katarzyna Kita, Catarina Albergaria, Ana S Machado, Megan R Carey, Martin Müller, Igor Delvendahl

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Clinical features of epileptic syndrome and alteration of NMDAand of AMPA-receptors of glutamate in the pathogenesis of the disease in the patients with supratentorial meningiomas of the brain by V. N. Ochkolyas, A. A. Skoromets, A. F. Gurchin

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GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors by Jithin D. Nair, Kevin A. Wilkinson, Busra P. Yucel, Christophe Mulle, Bryce Vissel, Jack Mellor, Jeremy M. Henley

“…GluK2(Q) mice also had fewer GluA1-and GluA3-containing AMPA receptors (AMPARs) and reduced postsynaptic AMPAR currents at both MF-CA3 and CA1-Schaffer collateral synapses. …”
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Ca²⁺-Permeable AMPA Receptors Contribute to Changed Dorsal Horn Neuronal Firing and Inflammatory Pain by Olga Kopach, Yulia Dobropolska, Pavel Belan, Nana Voitenko

“…The DH hyperexcitability (central sensitisation) has been considered a fundamental mechanism in mediating nociceptive hypersensitivity, with the proven role of Ca²⁺-permeable AMPA receptors (AMPARs). However, whether and how the DH hyperexcitability relates to changes in action potential (AP) parameters in DH neurons and if Ca²⁺-permeable AMPARs contribute to these changes remain unknown. …”
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Anti-NMDA and Anti-AMPA Receptor Antibodies in Central Disorders: Preclinical Approaches to Assess Their Pathological Role and Translatability to Clinic by Guendalina Olivero, Alessandra Roggeri, Anna Pittaluga

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MINK and TNIK Differentially Act on Rap2-Mediated Signal Transduction to Regulate Neuronal Structure and AMPA Receptor Function by Hussain, Natasha K., Hsin, Honor, Huganir, Richard L., Sheng, Morgan Hwa-Tze

“…Activated Rap2 has been found to stimulate dendritic pruning, reduce synaptic density and cause removal of synaptic AMPA receptors (AMPA-Rs) (Zhu et al., 2005; Fu et al., 2007). …”
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Calcium-permeable AMPA receptors provide a common mechanism for LTP in glutamatergic synapses of distinct hippocampal interneuron types. by Szabo, A, Somogyi, J, Cauli, B, Lambolez, B, Somogyi, P, Lamsa, K

“…Potentiation that depends on calcium-permeable (CP) AMPA receptors has been characterized in oriens-lacunosum moleculare (O-LM) interneurons, which express parvalbumin and somatostatin (SM). …”

Synergistic neuroprotective effects by combining an NMDA or AMPA receptor antagonist with nitric oxide synthase inhibitors in global cerebral ischaemia. by Hicks, C, Ward, M, Swettenham, J, O'Neill, M

“…We have investigated the neuroprotective effects of combining an NMDA or AMPA receptor antagonist with a nitric oxide synthase (NOS) inhibitor in the gerbil model of global cerebral ischaemia. …”

Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats. by Buchan, A, Li, H, Cho, S, Pulsinelli, W

“…The cytoprotective effect of NBQX, a selective AMPA receptor antagonist, was tested following 10 min of severe forebrain ischemia using the 4-vessel occlusion model. …”

Deletion of glutamate receptor-A (GluR-A) AMPA receptor subunits impairs one-trial spatial memory. by Sanderson, D, Gray, A, Simon, A, Taylor, A, Deacon, R, Seeburg, P, Sprengel, R, Good, M, Rawlins, J, Bannerman, D

“…Genetically modified mice lacking the glutamate receptor A (GluR-A) subunit of the AMPA receptor (GluR-A-/- mice) display normal spatial reference memory but impaired spatial working memory (SWM). …”

Insertion of Calcium-Permeable AMPA Receptors during Epileptiform Activity In Vitro Modulates Excitability of Principal Neurons in the Rat Entorhinal Cortex by Dmitry V. Amakhin, Elena B. Soboleva, Anton V. Chizhov, Aleksey V. Zaitsev

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Coupled feedback loops maintain synaptic long-term potentiation: A computational model of PKMzeta synthesis and AMPA receptor trafficking. by Peter Helfer, Thomas R Shultz

“…At the core of the model are two interlinked feedback loops of molecular reactions, one involving the atypical protein kinase PKMζ and its messenger RNA, the other involving PKMζ and GluA2-containing AMPA receptors. We demonstrate that robust bistability-stable equilibria both in the synapse's potentiated and unpotentiated states-can arise from a set of simple molecular reactions. …”
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Downregulation of surface AMPA receptor expression in the striatum following prolonged social isolation, a role of mGlu5 receptors by Li-Min Mao, Nirav Mathur, John Q. Wang

“…In these depressed rats, surface levels of AMPA receptors, mainly GluA1 and GluA3 subunits, were reduced in the nucleus accumbens (NAc). …”
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s-ketamine enhances thalamocortical and corticocortical synaptic transmission in acute murine brain slices via increased AMPA-receptor-mediated pathways by Matthias Bieber, Stefan Schwerin, Matthias Kreuzer, Claudia Klug, Marie Henzler, Gerhard Schneider, Rainer Haseneder, Stephan Kratzer

“…Both thalamocortical and intracortical AMPA-receptor-mediated EPSPs were significantly increased.In conclusion, our findings show no evidence for a NMDA-receptor antagonism-based disinhibition, but rather suggest an enhanced thalamocortical and intracortical synaptic transmission, which appears to be driven via increased AMPA-receptor-mediated transmission.…”
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