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Single-cell characterization of anti–LAG-3 and anti–PD-1 combination treatment in patients with melanoma
Published 2023-03-01“…Last, higher baseline TCR clonality was observed in responding patients, and their expanding CD8+ T cell clones gained a more cytotoxic and NK-like phenotype.Conclusion Anti–LAG-3+anti–PD-1 therapy has profound effects on NK cells and Tregs in addition to CD8+ T cells.Trial registration ClinicalTrials.gov (NCT01968109)Funding Cancer Foundation Finland, Sigrid Juselius Foundation, Signe and Ane Gyllenberg Foundation, Relander Foundation, State funding for university-level health research in Finland, a Helsinki Institute of Life Sciences Fellow grant, Academy of Finland (grant numbers 314442, 311081, 335432, and 335436), and an investigator-initiated research grant from BMS.…”
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Toward a novel Sustainability Transparency Index for improved governance in agri-food value chains: A comparative study of Finnish and Ukrainian companies
Published 2024-09-01“…Acknowledgment Inna Makarenko gratefully acknowledges the support of the Academy of Finland (Decision 353888). …”
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Q-Learning and Enhanced Policy Iteration in Discounted Dynamic Programming
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A Unifying Polyhedral Approximation Framework for Convex Optimization
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Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues
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A meshless hierarchical representation for light transport
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On dimension reduction in Gaussian filters
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MOVPE growth of N-polar AlN on 4H-SiC: Effect of substrate miscut on layer quality
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Heterogeneous somatostatin-expressing neuron population in mouse ventral tegmental area
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Impact of combined consumption of fish oil and probiotics on the serum metabolome in pregnant women with overweight or obesity
Published 2021-11-01“…Funding: State Research Funding for university-level health research in the Turku University Hospital Expert Responsibility Area, Academy of Finland, the Diabetes Research Foundation, the Juho Vainio Foundation, Janssen Research & Development, LLC.…”
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